What Can Genome-Wide Association Studies Tell Us about the Genetics of Common Disease

por Iles, Mark M
Publicado 2008

The Impact of Incomplete Linkage Disequilibrium and Genetic Model Choice on the Analysis and Interpretation of Genome-wide Association Studies

por Iles, Mark M
Publicado 2010

Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods

por Humphreys, Keith, Iles, Mark M
Publicado 2005

Ethnic-specific associations between dietary consumption and gestational diabetes mellitus incidence: A meta-analysis

por Fuller, Harriett, Moore, J. Bernadette, Iles, Mark M., Zulyniak, Michael A.
Publicado 2022

Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort

por Fuller, Harriett, Iles, Mark M., Moore, J. Bernadette, Zulyniak, Michael A.
Publicado 2023

Telomere length and common disease: study design and analytical challenges

por Barrett, Jennifer H., Iles, Mark M., Dunning, Alison M., Pooley, Karen A.
Publicado 2015

Interplay between demographic, clinical and polygenic risk factors for severe COVID-19

por Crossfield, Samantha S R, Chaddock, Natalie J M, Iles, Mark M, Pujades-Rodriguez, Mar, Morgan, Ann W
Publicado 2022

An Overview of Strategies for Detecting Genotype-Phenotype Associations Across Ancestrally Diverse Populations

por Simonin-Wilmer, Irving, Orozco-del-Pino, Pedro, Bishop, D. Timothy, Iles, Mark M., Robles-Espinoza, Carla Daniela
Publicado 2021

Analysis of variants in DNA damage signalling genes in bladder cancer

por Choudhury, Ananya, Elliott, Faye, Iles, Mark M, Churchman, Michael, Bristow, Robert G, Bishop, D Timothy, Kiltie, Anne E
Publicado 2008

Pathway-Based Analysis of a Melanoma Genome-Wide Association Study: Analysis of Genes Related to Tumour-Immunosuppression

por Schoof, Nils, Iles, Mark M., Bishop, D. Timothy, Newton-Bishop, Julia A., Barrett, Jennifer H., consortium, GenoMEL
Publicado 2011

Differences in the management of patients requiring an emergency resection for colonic cancer in two European populations

por Taylor, John C, Iversen, Lene H, Burke, Dermot, Finan, Paul J, Iles, Mark M, Morris, Eva J A, Quirke, Philip
Publicado 2022

Genetic Relationship Between Endometriosis and Melanoma

por Yang, Fei, Mortlock, Sally, MacGregor, Stuart, Iles, Mark M., Landi, Maria Teresa, Shi, Jianxin, Law, Matthew H., Montgomery, Grant W.
Publicado 2021

Linkage Disequilibrium Mapping of CHEK2: Common Variation and Breast Cancer Risk

por Einarsdóttir, Kristjana, Humphreys, Keith, Bonnard, Carine, Palmgren, Juni, Iles, Mark M, Sjölander, Arvid, Li, Yuqing, Chia, Kee Seng, Liu, Edison T, Hall, Per, Liu, Jianjun, Wedrén, Sara
Publicado 2006

Genetic variants for smoking behaviour and risk of skin cancer

por Dusingize, Jean Claude, Law, Matthew H., Seviiri, Mathias, Olsen, Catherine M., Pandeya, Nirmala, Landi, Maria Teresa, Iles, Mark M., Neale, Rachel E., Ong, Jue-Sheng, MacGregor, Stuart, Whiteman, David C.
Publicado 2023

Multi-Variant Pathway Association Analysis Reveals the Importance of Genetic Determinants of Estrogen Metabolism in Breast and Endometrial Cancer Susceptibility

por Low, Yen Ling, Li, Yuqing, Humphreys, Keith, Thalamuthu, Anbupalam, Li, Yi, Darabi, Hatef, Wedrén, Sara, Bonnard, Carine, Czene, Kamila, Iles, Mark M., Heikkinen, Tuomas, Aittomäki, Kristiina, Blomqvist, Carl, Nevanlinna, Heli, Hall, Per, Liu, Edison T., Liu, Jianjun
Publicado 2010

Defining novel causal SNPs and linked phenotypes at melanoma-associated loci

por Castaneda-Garcia, Carolina, Iyer, Vivek, Nsengimana, Jérémie, Trower, Adam, Droop, Alastair, Brown, Kevin M, Choi, Jiyeon, Zhang, Tongwu, Harland, Mark, Newton-Bishop, Julia A, Bishop, D Timothy, Adams, David J, Iles, Mark M, Robles-Espinoza, Carla Daniela
Publicado 2022

Association between a 46-SNP Polygenic Risk Score and melanoma risk in Dutch patients with familial melanoma

por Potjer, Thomas P, van der Grinten, Tara W J, Lakeman, Inge M M, Bollen, Sander H, Rodríguez-Girondo, Mar, Iles, Mark M, Barrett, Jennifer H, Kiemeney, Lambertus A, Gruis, Nelleke A, van Asperen, Christi J, van der Stoep, Nienke
Publicado 2021

Fine-scale population structure and demographic history of British Pakistanis

por Arciero, Elena, Dogra, Sufyan A., Malawsky, Daniel S., Mezzavilla, Massimo, Tsismentzoglou, Theofanis, Huang, Qin Qin, Hunt, Karen A., Mason, Dan, Sharif, Saghira Malik, van Heel, David A., Sheridan, Eamonn, Wright, John, Small, Neil, Carmi, Shai, Iles, Mark M., Martin, Hilary C.
Publicado 2021

Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts

por Steinberg, Julia, Iles, Mark M., Lee, Jin Yee, Wang, Xiaochuan, Law, Matthew H., Smit, Amelia K., Nguyen‐Dumont, Tu, Giles, Graham G., Southey, Melissa C., Milne, Roger L., Mann, Graham J., Bishop, D. Timothy, MacInnis, Robert J., Cust, Anne E.
Publicado 2022

Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes

por Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A., Shi, Jianxin, Xu, Mai, Goldstein, Alisa M., Trower, Adam J., Bishop, D. Timothy, Iles, Mark M., Duffy, David L., MacGregor, Stuart, Amundadottir, Laufey T., Law, Matthew H., Loftus, Stacie K., Pavan, William J., Brown, Kevin M.
Publicado 2018