A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1–MMP

por Shiryaev, S A, Remacle, A G, Golubkov, V S, Ingvarsen, S, Porse, A, Behrendt, N, Cieplak, P, Strongin, A Y
Publicado 2013

Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo

por Lund, Ida K., Rasch, Morten G., Ingvarsen, Signe, Pass, Jesper, Madsen, Daniel H., Engelholm, Lars H., Behrendt, Niels, Høyer-Hansen, Gunilla
Publicado 2012

Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis

por Madsen, Daniel H., Jürgensen, Henrik J., Ingvarsen, Signe, Melander, Maria C., Albrechtsen, Reidar, Hald, Andreas, Holmbeck, Kenn, Bugge, Thomas H., Behrendt, Niels, Engelholm, Lars H.
Publicado 2013

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

por Rowe, R. Grant, Li, Xiao-Yan, Hu, Yuexian, Saunders, Thomas L., Virtanen, Ismo, de Herreros, Antonio Garcia, Becker, Karl-Friedrich, Ingvarsen, Signe, Engelholm, Lars H., Bommer, Guido T., Fearon, Eric R., Weiss, Stephen J.
Publicado 2009

Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

por Ingvarsen, Signe Z., Gårdsvoll, Henrik, van Putten, Sander, Nørregaard, Kirstine S., Krigslund, Oliver, Meilstrup, Josephine A., Tran, Collin, Jürgensen, Henrik J., Melander, Maria C., Nielsen, Carsten H., Kjaer, Andreas, Bugge, Thomas H., Engelholm, Lars H., Behrendt, Niels
Publicado 2020

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

por Nielsen, Christoffer Fagernæs, van Putten, Sander Maarten, Lund, Ida Katrine, Melander, Maria Carlsén, Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, Kristian, Christensen, Kristine Rothaus, Ingvarsen, Signe Ziir, Gårdsvoll, Henrik, Jensen, Kamilla Ellermann, Hamerlik, Petra, Engelholm, Lars Henning, Behrendt, Niels
Publicado 2017