Investigating Mammalian Formins with SMIFH2 Fifteen Years in: Novel Targets and Unexpected Biology

por Innocenti, Metello
Publicado 2023

SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton

por Isogai, Tadamoto, van der Kammen, Rob, Innocenti, Metello
Publicado 2015

mDia1 Assembles a Linear F-Actin Coat at Membrane Invaginations To Drive Listeria monocytogenes Cell-to-Cell Spreading

por Dhanda, Aaron S., Vogl, A. Wayne, Ness, Fern, Innocenti, Metello, Guttman, Julian A.
Publicado 2021

Mechanisms through which Sos-1 coordinates the activation of Ras and Rac

por Innocenti, Metello, Tenca, Pierluigi, Frittoli, Emanuela, Faretta, Mario, Tocchetti, Arianna, Di Fiore, Pier Paolo, Scita, Giorgio
Publicado 2002

PFA fixation enables artifact-free super-resolution imaging of the actin cytoskeleton and associated proteins

por Leyton-Puig, Daniela, Kedziora, Katarzyna M., Isogai, Tadamoto, van den Broek, Bram, Jalink, Kees, Innocenti, Metello
Publicado 2016

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1

por Innocenti, Metello, Frittoli, Emanuela, Ponzanelli, Isabella, Falck, John R., Brachmann, Saskia M., Di Fiore, Pier Paolo, Scita, Giorgio
Publicado 2003

Proteomic Analyses Uncover a New Function and Mode of Action for Mouse Homolog of Diaphanous 2 (mDia2)

por Isogai, Tadamoto, van der Kammen, Rob, Goerdayal, Soenita S., Heck, Albert J. R., Altelaar, A. F. Maarten, Innocenti, Metello
Publicado 2015

Advanced Cell Culture Models Illuminate the Interplay between Mammary Tumor Cells and Activated Fibroblasts

por Del Nero, Martina, Colombo, Alessandro, Garbujo, Stefania, Baioni, Chiara, Barbieri, Linda, Innocenti, Metello, Prosperi, Davide, Colombo, Miriam, Fiandra, Luisa
Publicado 2023

Flat clathrin lattices are dynamic actin-controlled hubs for clathrin-mediated endocytosis and signalling of specific receptors

por Leyton-Puig, Daniela, Isogai, Tadamoto, Argenzio, Elisabetta, van den Broek, Bram, Klarenbeek, Jeffrey, Janssen, Hans, Jalink, Kees, Innocenti, Metello
Publicado 2017

A Protumorigenic mDia2–MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts

por Cangkrama, Michael, Liu, Huan, Whipman, James, Zubair, Maria, Matsushita, Mai, Di Filippo, Michela, Kopf, Manfred, Innocenti, Metello, Werner, Sabine
Publicado 2022

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA–mDia2 signaling and filopodium formation

por Argenzio, Elisabetta, Klarenbeek, Jeffrey, Kedziora, Katarzyna M., Nahidiazar, Leila, Isogai, Tadamoto, Perrakis, Anastassis, Jalink, Kees, Moolenaar, Wouter H., Innocenti, Metello
Publicado 2018

A paracrine activin A–mDia2 axis promotes squamous carcinogenesis via fibroblast reprogramming

por Cangkrama, Michael, Wietecha, Mateusz, Mathis, Nicolas, Okumura, Rin, Ferrarese, Luca, Al‐Nuaimi, Dunja, Antsiferova, Maria, Dummer, Reinhard, Innocenti, Metello, Werner, Sabine
Publicado 2020

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin–polymerizing machine

por Scita, Giorgio, Tenca, Pierluigi, Areces, Liliana B., Tocchetti, Arianna, Frittoli, Emanuela, Giardina, Giuseppina, Ponzanelli, Isabella, Sini, Patrizia, Innocenti, Metello, Di Fiore, Pier Paolo
Publicado 2001