The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age

por Inshaw, Jamie R. J., Walker, Neil M., Wallace, Chris, Bottolo, Leonardo, Todd, John A.
Publicado 2017

Thymocyte regulatory variant alters transcription factor binding and protects from type 1 diabetes in infants

por Sandholm, Niina, Rubio García, Arcadio, Pekalski, Marcin L., Inshaw, Jamie R. J., Cutler, Antony J., Todd, John A.
Publicado 2022

Analysis of overlapping genetic association in type 1 and type 2 diabetes

por Inshaw, Jamie R. J., Sidore, Carlo, Cucca, Francesco, Stefana, M. Irina, Crouch, Daniel J. M., McCarthy, Mark I., Mahajan, Anubha, Todd, John A.
Publicado 2021

Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach

por Richardson, Tom G., Crouch, Daniel J. M., Power, Grace M., Morales-Berstein, Fernanda, Hazelwood, Emma, Fang, Si, Cho, Yoonsu, Inshaw, Jamie R. J., Robertson, Catherine C., Sidore, Carlo, Cucca, Francesco, Rich, Steven S., Todd, John A., Davey Smith, George
Publicado 2022

Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration

por Carr, Alice L.J., Inshaw, Jamie R.J., Flaxman, Christine S., Leete, Pia, Wyatt, Rebecca C., Russell, Lydia A., Palmer, Matthew, Prasolov, Dmytro, Worthington, Thomas, Hull, Bethany, Wicker, Linda S., Dunger, David B., Oram, Richard A., Morgan, Noel G., Todd, John A., Richardson, Sarah J., Besser, Rachel E.J.
Publicado 2022

The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes

por Ramos-Rodríguez, Mireia, Raurell-Vila, Helena, Colli, Maikel L., Alvelos, Maria Inês, Subirana-Granés, Marc, Juan-Mateu, Jonàs, Norris, Richard, Turatsinze, Jean-Valery, Nakayasu, Ernesto S., Webb-Robertson, Bobbie-Jo M., Inshaw, Jamie R.J., Marchetti, Piero, Piemonti, Lorenzo, Esteller, Manel, Todd, John A., Metz, Thomas O., Eizirik, Décio L., Pasquali, Lorenzo
Publicado 2019

Fine-mapping, trans-ancestral, and genomic analyses identify causal variants, cells, genes, and drug targets for type 1 diabetes

por Robertson, Catherine C., Inshaw, Jamie R. J., Onengut-Gumuscu, Suna, Chen, Wei-Min, Santa Cruz, David Flores, Yang, Hanzhi, Cutler, Antony J., Crouch, Daniel J. M., Farber, Emily, Bridges, S. Louis, Edberg, Jeffrey C., Kimberly, Robert P., Buckner, Jane H., Deloukas, Panos, Divers, Jasmin, Dabelea, Dana, Lawrence, Jean M., Marcovina, Santica, Shah, Amy S., Greenbaum, Carla J., Atkinson, Mark A., Gregersen, Peter K., Oksenberg, Jorge R., Pociot, Flemming, Rewers, Marian J., Steck, Andrea K., Dunger, David B., Wicker, Linda S., Concannon, Patrick, Todd, John A., Rich, Stephen S.
Publicado 2021