Reversibility of liver fibrosis

por Pellicoro, Antonella, Ramachandran, Prakash, Iredale, John P
Publicado 2012

Hepatic Lipocytes, TIMP-1 and Liver Fibrosis

por Arthur, Michael J P, Iredale, John P
Publicado 1994

Origins of fibrosis: pericytes take centre stage

por Greenhalgh, Stephen N., Iredale, John P., Henderson, Neil C.
Publicado 2013

Tissue Inhibitor of Metalloproteinase-1 Inhibits Apoptosis of Rat and Human Hepatic Stellate Cells In Vitro

por Murphy, Frank R., Issa, Razao, Benyon, Christopher, Iredale, John P.
Publicado 2001

Managing uncertainty in advanced liver disease: a qualitative, multiperspective, serial interview study

por Kimbell, Barbara, Boyd, Kirsty, Kendall, Marilyn, Iredale, John, Murray, Scott A
Publicado 2015

Integration of geoscience frameworks into digital pathology analysis permits quantification of microarchitectural relationships in histological landscapes

por Kendall, Timothy J., Duff, Catherine M., Thomson, Andrew M., Iredale, John P.
Publicado 2020

Maintaining Hepatic Stem Cell Gene Expression on Biological and Synthetic Substrata

por Lucendo-Villarin, Baltasar, Khan, Ferdous, Pernagallo, Salvatore, Bradley, Mark, Iredale, John P., Hay, David C.
Publicado 2012

An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias

por Lynch, Ruairi W., Hawley, Catherine A., Pellicoro, Antonella, Bain, Calum C., Iredale, John P., Jenkins, Stephen J.
Publicado 2018

N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1

por Murphy, Frank, Waung, Julian, Collins, Jane, Arthur, Michael JP, Nagase, Hideaki, Mann, Derek, Benyon, R Christopher, Iredale, John P
Publicado 2004

Embryonic mesothelial-derived hepatic lineage of quiescent and heterogenous scar-orchestrating cells defined but suppressed by WT1

por Kendall, Timothy James, Duff, Catherine Mary, Boulter, Luke, Wilson, David H., Freyer, Elisabeth, Aitken, Stuart, Forbes, Stuart John, Iredale, John Peter, Hastie, Nicholas Dixon
Publicado 2019

Proteinase Activated Receptor 1 Mediated Fibrosis in a Mouse Model of Liver Injury: A Role for Bone Marrow Derived Macrophages

por Kallis, Yiannis N., Scotton, Christopher J., MacKinnon, Alison C., Goldin, Robert D., Wright, Nicholas A., Iredale, John P., Chambers, Rachel C., Forbes, Stuart J.
Publicado 2014

Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis

por Macfarlane, David P., Zou, Xiantong, Andrew, Ruth, Morton, Nicholas M., Livingstone, Dawn E. W., Aucott, Rebecca L., Nyirenda, Moffat J., Iredale, John P., Walker, Brian R.
Publicado 2011

Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice

por Michailidou, Zoi, Turban, Sophie, Miller, Eileen, Zou, Xiantong, Schrader, Joerg, Ratcliffe, Peter J., Hadoke, Patrick W. F., Walker, Brian R., Iredale, John P., Morton, Nicholas M., Seckl, Jonathan R.
Publicado 2012

Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells

por Lucendo-Villarin, Baltasar, Filis, Panagiotis, Swortwood, Madeleine J., Huestis, Marilyn A., Meseguer-Ripolles, Jose, Cameron, Kate, Iredale, John P., O’Shaughnessy, Peter J., Fowler, Paul A., Hay, David C.
Publicado 2017

SUMOylation of HNF4α regulates protein stability and hepatocyte function

por Zhou, Wenli, Hannoun, Zara, Jaffray, Ellis, Medine, Claire N., Black, James R., Greenhough, Sebastian, Zhu, Liang, Ross, James A., Forbes, Stuart, Wilmut, Ian, Iredale, John P., Hay, Ronald T., Hay, David C.
Publicado 2012

Macrophage derived Wnt signalling opposes Notch signalling in a Numb mediated manner to specify HPC fate in chronic liver disease in human and mouse

por Boulter, Luke, Govaere, Olivier, Bird, Tom G, Radulescu, Sorina, Ramachandran, Prakash, Pellicoro, Antonella, Ridgway, Rachel A, Seo, Sang Soo, Spee, Bart, Van Rooijen, Nico, Sansom, Owen J., Iredale, John P, Lowell, Sally, Roskams, Tania, Forbes, Stuart J
Publicado 2012

11Beta‐hydroxysteroid dehydrogenase‐1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis

por Zou, Xiantong, Ramachandran, Prakash, Kendall, Timothy J., Pellicoro, Antonella, Dora, Elena, Aucott, Rebecca L., Manwani, Kajal, Man, Tak Yung, Chapman, Karen E., Henderson, Neil C., Forbes, Stuart J., Webster, Scott P., Iredale, John P., Walker, Brian R., Michailidou, Zoi
Publicado 2018

In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis

por McBride, Andrew, Hoy, Anna M., Bamford, Mark J., Mossakowska, Danuta E., Ruediger, Martin P., Griggs, Jeremy, Desai, Sapna, Simpson, Kate, Caballero-Hernandez, Ivan, Iredale, John P., Pell, Theresa, Aucott, Rebecca L., Holmes, Duncan S., Webster, Scott P., Fallowfield, Jonathan A.
Publicado 2017

Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration

por Greenhalgh, Stephen N., Matchett, Kylie P., Taylor, Richard S., Huang, Katherine, Li, John T., Saeteurn, Koy, Donnelly, Mhairi C., Simpson, Eilidh E.M., Pollack, Joshua L., Atakilit, Amha, Simpson, Kenneth J., Maher, Jacquelyn J., Iredale, John P., Sheppard, Dean, Henderson, Neil C.
Publicado 2019

Low dose dexamethasone as treatment for women with heavy menstrual bleeding: A response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM)

por Warner, Pamela, Whitaker, Lucy Harriet Ravenscroft, Parker, Richard Anthony, Weir, Christopher John, Douglas, Anne, Hansen, Christian Holm, Madhra, Mayank, Hillier, Stephen Gilbert, Saunders, Philippa Tansy Kemp, Iredale, John Peter, Semple, Scott, Slayden, Ov Daniel, Walker, Brian Robert, Critchley, Hilary Octavia Dawn
Publicado 2021