Zika (PRVABC59) Infection Is Associated with T cell Infiltration and Neurodegeneration in CNS of Immunocompetent Neonatal C57Bl/6 Mice

por Manangeeswaran, Mohanraj, Ireland, Derek D. C., Verthelyi, Daniela
Publicado 2016

IL-12 and Viral Infections

por Komastu, Takashi, Ireland, Derek D.C, Reiss, Carol Shoshkes
Publicado 1998

Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities

por Polumuri, Swamy Kumar, Haile, Lydia A., Ireland, Derek D. C., Verthelyi, Daniela
Publicado 2018

CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF

por Manangeeswaran, Mohanraj, Lewkowicz, Aaron P., Israely, Tomer, Ireland, Derek D.C., Verthelyi, Daniela
Publicado 2020

IL-6 Impairs Vaccine Responses in Neonatal Mice

por Yang, Jiyeon, Sakai, Jiro, Siddiqui, Shafiuddin, Lee, Robert C., Ireland, Derek D. C., Verthelyi, Daniela, Akkoyunlu, Mustafa
Publicado 2018

Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients

por Thacker, Seth G., Her, Cheng, Kelley-Baker, Logan, Ireland, Derek D C., Manangeeswaran, Mohanraj, Pang, Eric S., Verthelyi, Daniela
Publicado 2022

Neonatal Zika virus infection causes transient perineuronal net degradation

por Engel, Kaliroi, Lee, Ha-Na, Tewari, Bhanu P., Lewkowicz, Aaron P., Ireland, Derek D. C., Manangeeswaran, Mohanraj, Verthelyi, Daniela
Publicado 2023

Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders

por Mou, Ta-Chung M., Lane, Malcolm V., Ireland, Derek D.C., Verthelyi, Daniela, Tonelli, Leonardo H., Clark, Sarah M.
Publicado 2022

RNase L Mediated Protection from Virus Induced Demyelination

por Ireland, Derek D. C., Stohlman, Stephen A., Hinton, David R., Kapil, Parul, Silverman, Robert H., Atkinson, Roscoe A., Bergmann, Cornelia C.
Publicado 2009

NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice

por Lee, Ha-Na, Manangeeswaran, Mohanraj, Lewkowicz, Aaron P., Engel, Kaliroi, Chowdhury, Monica, Garige, Mamatha, Eckhaus, Michael A., Sourbier, Carole, Ireland, Derek D.C., Verthelyi, Daniela
Publicado 2022

ZIKA virus infection causes persistent chorioretinal lesions

por Manangeeswaran, Mohanraj, Kielczewski, Jennifer L., Sen, H. Nida, Xu, Biying C., Ireland, Derek. D.C., McWilliams, Ian L., Chan, Chi-Chao, Caspi, Rachel R., Verthelyi, Daniela
Publicado 2018

Characterization of the therapeutic effect of antibodies targeting the Ebola glycoprotein using a novel BSL2-compliant rVSVΔG-EBOV-GP infection model

por Lee, Ha-Na, McWilliams, Ian L., Lewkowicz, Aaron P., Engel, Kaliroi, Ireland, Derek D. C., Kelley-Baker, Logan, Thacker, Seth, Piccardo, Pedro, Manangeeswaran, Mohanraj, Verthelyi, Daniela
Publicado 2021

Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice

por Ireland, Derek D. C., Manangeeswaran, Mohanraj, Lewkowicz, Aaron P., Engel, Kaliroi, Clark, Sarah M., Laniyan, Adelle, Sykes, Jacob, Lee, Ha-Na, McWilliams, Ian L., Kelley-Baker, Logan, Tonelli, Leonardo H., Verthelyi, Daniela
Publicado 2020

BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein

por Manangeeswaran, Mohanraj, Ireland, Derek D. C., Thacker, Seth G., Lee, Ha-Na, Kelley-Baker, Logan, Lewkowicz, Aaron P., Rothlauf, Paul W., Cornejo Pontelli, Marjorie, Bloyet, Louis-Marie, Eckhaus, Michael A., Mendoza, Mirian I., Whelan, Sean, Verthelyi, Daniela
Publicado 2022