Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes

por Diez-Iriepa, Daniel, Iriepa, Isabel, López-Muñoz, Francisco, Marco-Contelles, José, Hadjipavlou-Litina, Dimitra
Publicado 2022

N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

por Bautista-Aguilera, Óscar M., Alonso, José M., Catto, Marco, Iriepa, Isabel, Knez, Damijan, Gobec, Stanislav, Marco-Contelles, José
Publicado 2022

Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease

por Rampa, Angela, Bartolini, Manuela, Pruccoli, Letizia, Naldi, Marina, Iriepa, Isabel, Moraleda, Ignacio, Belluti, Federica, Gobbi, Silvia, Tarozzi, Andrea, Bisi, Alessandra
Publicado 2018

Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy

por Zribi, Lazhar, Pachòn-Angona, Irene, Bautista-Aguilera, Òscar M., Diez-Iriepa, Daniel, Marco-Contelles, José, Ismaili, Lhassane, Iriepa, Isabel, Chabchoub, Fakher
Publicado 2020

Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates

por Petcu, A. Sonia, Lázaro-Milla, Carlos, Rodríguez, F. Javier, Iriepa, Isabel, Bautista-Aguilera, Óscar M., Aragoncillo, Cristina, Alonso, José M., Almendros, Pedro
Publicado 2023

Homo-Tris-Nitrones Derived from α-Phenyl-N-tert-butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties

por Diez-Iriepa, Daniel, Chamorro, Beatriz, Talaván, Marta, Chioua, Mourad, Iriepa, Isabel, Hadjipavlou-Litina, Dimitra, López-Muñoz, Francisco, Marco-Contelles, José, Oset-Gasque, María Jesús
Publicado 2020

Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment

por Diez-Iriepa, Daniel, Knez, Damijan, Gobec, Stanislav, Iriepa, Isabel, de los Ríos, Cristóbal, Bravo, Isaac, López-Muñoz, Francisco, Marco-Contelles, José, Hadjipavlou-Litina, Dimitra
Publicado 2022

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR ana...

por Bautista-Aguilera, Oscar M, Esteban, Gerard, Chioua, Mourad, Nikolic, Katarina, Agbaba, Danica, Moraleda, Ignacio, Iriepa, Isabel, Soriano, Elena, Samadi, Abdelouahid, Unzeta, Mercedes, Marco-Contelles, José
Publicado 2014

Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer′s Disease Therapy

por Boulebd, Houssem, Ismaili, Lhassane, Bartolini, Manuela, Bouraiou, Abdelmalek, Andrisano, Vincenza, Martin, Helene, Bonet, Alexandre, Moraleda, Ignacio, Iriepa, Isabel, Chioua, Mourad, Belfaitah, Ali, Marco-Contelles, José
Publicado 2016

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

por Pachón Angona, Irene, Martin, Helene, Daniel, Solene, Moraleda, Ignacio, Bonet, Alexandre, Wnorowski, Artur, Maj, Maciej, Jozwiak, Krzysztof, Iriepa, Isabel, Refouvelet, Bernard, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2020

Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer’s Disease

por Alonso, José M., Escobar-Peso, Alejandro, Palomino-Antolín, Alejandra, Diez-Iriepa, Daniel, Chioua, Mourad, Martínez-Alonso, Emma, Iriepa, Isabel, Egea, Javier, Alcázar, Alberto, Marco-Contelles, José
Publicado 2021

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy

por Ramos, Eva, Palomino-Antolín, Alejandra, Bartolini, Manuela, Iriepa, Isabel, Moraleda, Ignacio, Diez-Iriepa, Daniel, Samadi, Abdelouahid, Cortina, Carol V., Chioua, Mourad, Egea, Javier, Romero, Alejandro, Marco-Contelles, José
Publicado 2019

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy

por Pachón-Angona, Irene, Refouvelet, Bernard, Andrýs, Rudolf, Martin, Helène, Luzet, Vincent, Iriepa, Isabel, Moraleda, Ignacio, Diez-Iriepa, Daniel, Oset-Gasque, María-Jesús, Marco-Contelles, José, Musilek, Kamil, Ismaili, Lhassane
Publicado 2019

Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

por Dakhlaoui, Imen, Bernard, Paul J., Pietrzak, Diana, Simakov, Alexey, Maj, Maciej, Refouvelet, Bernard, Béduneau, Arnaud, Cornu, Raphaël, Jozwiak, Krzysztof, Chabchoub, Fakher, Iriepa, Isabel, Martin, Helene, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2023

Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapy

por Dgachi, Youssef, Martin, Hélène, Malek, Rim, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Iriepa, Isabel, Moraleda, Ignacio, Maalej, Emna, Carreiras, M. Carmo, Refouvelet, Bernard, Chabchoub, Fakher, Marco-Contelles, José, Ismaili, Lhassane
Publicado 2018

Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer’s Disease Therapy

por Bautista-Aguilera, Óscar M., Ismaili, Lhassane, Chioua, Mourad, Andrys, Rudolf, Schmidt, Monika, Bzonek, Petr, Martínez-Grau, María Ángeles, Beadle, Christopher D., Vetman, Tatiana, López-Muñoz, Francisco, Iriepa, Isabel, Refouvelet, Bernard, Musilek, Kamil, Marco-Contelles, José
Publicado 2020

Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models

por Chamorro, Beatriz, Diez-Iriepa, Daniel, Merás-Sáiz, Belén, Chioua, Mourad, García-Vieira, David, Iriepa, Isabel, Hadjipavlou-Litina, Dimitra, López-Muñoz, Francisco, Martínez-Murillo, Ricardo, Gonzàlez-Nieto, Daniel, Fernández, Israel, Marco-Contelles, José, Oset-Gasque, María Jesús
Publicado 2020

Chromenones as Multineurotargeting Inhibitors of Human Enzymes

por Lemke, Carina, Christmann, Joscha, Yin, Jiafei, Alonso, José M., Serrano, Estefanía, Chioua, Mourad, Ismaili, Lhassane, Martínez-Grau, María Angeles, Beadle, Christopher D., Vetman, Tatiana, Dato, Florian M., Bartz, Ulrike, Elsinghorst, Paul W., Pietsch, Markus, Müller, Christa E., Iriepa, Isabel, Wille, Timo, Marco-Contelles, José, Gütschow, Michael
Publicado 2019