Systemic delivery of liposome-anchored anti-CD137 and IL2-Fc prevents lethal toxicity and elicits potent antitumor immunity

por Zhang, Yuan, Irvine, Darrell J
Publicado 2015

Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy**

por Liu, Haipeng, Kwong, Brandon, Irvine, Darrell J
Publicado 2011

Controlling timing and location in vaccines

por Irvine, Darrell J., Aung, Aereas, Silva, Murillo
Publicado 2020

Engineering autoreactive T and B cell responses toward active immunotherapy for inflammatory diseases

por Chang, Jason Y. H., Irvine, Darrell J.
Publicado 2021

Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

por Bhagchandani, Sachin, Johnson, Jeremiah, Irvine, Darrell J.
Publicado 2021

T lymphocyte engineering with cytokine nanogels for enhanced cancer immunotherapy

por Tang, Li, Zheng, Yiran, Mabardi, Llian, Irvine, Darrell J
Publicado 2015

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

por Zhang, Yuan, Li, Na, Suh, Heikyung, Irvine, Darrell J.
Publicado 2018

Synergistic Antitumor Activity from Two-Stage Delivery of Targeted Toxins and Endosome-Disrupting Nanoparticles

por Su, Xingfang, Yang, Nicole, Wittrup, K. Dane, Irvine, Darrell J.
Publicado 2013

Not All T Cell Synapses Are Built the Same Way

por Kumari, Sudha, Colin-York, Huw, Irvine, Darrell J., Fritzsche, Marco
Publicado 2019

Antigen Delivery by Lipid-Enveloped PLGA Microparticle Vaccines Mediated by in Situ Vesicle Shedding

por Hanson, Melissa C., Bershteyn, Anna, Crespo, Monica P., Irvine, Darrell J.
Publicado 2014

Therapeutic cell engineering using surface-conjugated synthetic nanoparticles

por Stephan, Matthias T., Moon, James J., Um, Soong Ho, Bershteyn, Anna, Irvine, Darrell J.
Publicado 2010

Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells

por Palmer, Megan J, Mahajan, Vinay S, Chen, Jianzhu, Irvine, Darrell J, Lauffenburger, Douglas A
Publicado 2011

Design of Lipid Nanocapsule Delivery Vehicles for Multivalent Display of Recombinant Env Trimers in HIV Vaccination

por Pejawar-Gaddy, Sharmila, Kovacs, James M., Barouch, Dan H., Chen, Bing, Irvine, Darrell J.
Publicado 2014

Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer

por Draganov, Dobrin, Han, Zhen, Rana, Aamir, Bennett, Nitasha, Irvine, Darrell J., Lee, Peter P.
Publicado 2021

Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade

por Sriram, Ganapathy, Emmons, Tiffany R., Milling, Lauren E., Irvine, Darrell J., Yaffe, Michael B.
Publicado 2022

Freely Suspended Cellular “Backpacks” Lead to Cell Aggregate Self-Assembly

por Swiston, Albert J., Gilbert, Jonathan B., Irvine, Darrell J., Cohen, Robert E., Rubner, Michael F.
Publicado 2010

Block Copolymer Micelles as Nanocontainers for Controlled Release of Proteins from Biocompatible Oil Phases

por Miller, Andrew C., Bershteyn, Anna, Tan, Wuisiew, Hammond, Paula T., Cohen, Robert E., Irvine, Darrell J.
Publicado 2009

DNA-Loaded Cationic Liposomes Efficiently Function as a Vaccine against Malarial Proteins

por Fotoran, Wesley L., Santangelo, Rachele, de Miranda, Beatriz N.M., Irvine, Darrell J., Wunderlich, Gerhard
Publicado 2017

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine

por Moon, James J., Suh, Heikyung, Polhemus, Mark E., Ockenhouse, Christian F., Yadava, Anjali, Irvine, Darrell J.
Publicado 2012

Composite Dissolving Microneedles for Coordinated Control of Antigen and Adjuvant Delivery Kinetics in Transcutaneous Vaccination

por DeMuth, Peter C, Garcia-Beltran, Wilfredo F, Ai-Ling, Michelle Lim, Hammond, Paula T, Irvine, Darrell J
Publicado 2013