Frontiers in therapeutic development of allopregnanolone for Alzheimer’s disease and other neurological disorders

por Irwin, Ronald W., Solinsky, Christine M., Brinton, Roberta Diaz
Publicado 2014

Neuroregenerative Mechanisms of Allopregnanolone in Alzheimer’s Disease

por Irwin, Ronald W., Wang, Jun Ming, Chen, Shuhua, Brinton, Roberta Diaz
Publicado 2012

Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function

por Nilsen, Jon, Chen, Shuhua, Irwin, Ronald W, Iwamoto, Sean, Brinton, Roberta Diaz
Publicado 2006

Regeneration in a Degenerating Brain: Potential of Allopregnanolone as a Neuroregenerative Agent

por Ming Wang, Jun, Irwin, Ronald W, Liu, Lifei, Chen, Shuhua, Brinton, Roberta Diaz
Publicado 2007

Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease

por Chen, Shuhua, Wang, Jun Ming, Irwin, Ronald W., Yao, Jia, Liu, Lifei, Brinton, Roberta Diaz
Publicado 2011

Allopregnanolone Preclinical Acute Pharmacokinetic and Pharmacodynamic Studies to Predict Tolerability and Efficacy for Alzheimer’s Disease

por Irwin, Ronald W., Solinsky, Christine M., Loya, Carlos M., Salituro, Francesco G., Rodgers, Kathleen E., Bauer, Gerhard, Rogawski, Michael A., Brinton, Roberta Diaz
Publicado 2015

A Dominant Negative ERβ Splice Variant Determines the Effectiveness of Early or Late Estrogen Therapy after Ovariectomy in Rats

por Wang, Jun Ming, Hou, Xu, Adeosun, Samuel, Hill, Rosanne, Henry, Sherry, Paul, Ian, Irwin, Ronald W., Ou, Xiao-Ming, Bigler, Steven, Stockmeier, Craig, Brinton, Roberta Diaz, Gomez-Sanchez, Elise
Publicado 2012