Considerations for the Assessment of Substrates, Genetics and Risk Factors in Patients with Atrial Fibrillation

por Linz, Dominik, Verheule, Sander, Isaacs, Aaron, Schotten, Ulrich
Publicado 2021

Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality

por Brouwers, Martijn C. G. J., Simons, Nynke, Stehouwer, Coen D. A., Isaacs, Aaron
Publicado 2019

Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease

por Brouwers, Martijn C.G.J., Simons, Nynke, Stehouwer, Coen D.A., Koek, Ger H., Schaper, Nicolaas C., Isaacs, Aaron
Publicado 2019

Preoperative P-wave parameters and risk of atrial fibrillation after cardiac surgery: a meta-analysis of 20 201 patients

por Kawczynski, Michal J, Van De Walle, Sophie, Maesen, Bart, Isaacs, Aaron, Zeemering, Stef, Hermans, Ben, Vernooy, Kevin, Maessen, Jos G, Schotten, Ulrich, Bidar, Elham
Publicado 2022

Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval

por Silva, Claudia Tamar, Kors, Jan A., Amin, Najaf, Dehghan, Abbas, Witteman, Jacqueline C. M., Willemsen, Rob, Oostra, Ben A., van Duijn, Cornelia M., Isaacs, Aaron
Publicado 2015

Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes

por Jainandunsing, Sjaam, Özcan, Behiye, Rietveld, Trinet, van Miert, Joram N. I., Isaacs, Aaron J., Langendonk, Janneke G., de Rooij, Felix W. M., Sijbrands, Eric J. G.
Publicado 2014

New-onset perioperative atrial fibrillation in cardiac surgery patients: transient trouble or persistent problem?—Authors’ reply

por Kawczynski, Michal J, Zeemering, Stef, Gilbers, Martijn, Isaacs, Aaron, Verheule, Sander, Zink, Matthias D, Maesen, Bart, Bramer, Sander, Van Gelder, Isabelle C, Crijns, Harry J G M, Schotten, Ulrich, Bidar, Elham
Publicado 2021

Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77

por Christ, Anette, Goossens, Pieter G., Wijnands, Erwin, Jin, Han, Legein, Bart, Oth, Tammy, Isaacs, Aaron, Stoll, Monika, Vanderlocht, Joris, Lutgens, Esther, Daemen, Mat J. A. P., Zenke, Martin, Biessen, Erik A. L.
Publicado 2022

Clinical and electrophysiological predictors of device-detected new-onset atrial fibrillation during 3 years after cardiac surgery

por Bidar, Elham, Zeemering, Stef, Gilbers, Martijn, Isaacs, Aaron, Verheule, Sander, Zink, Matthias D, Maesen, Bart, Bramer, Sander, Kawczynski, Michal, Van Gelder, Isabelle C, Crijns, Harry J G M, Maessen, Jos G, Schotten, Ulrich
Publicado 2021

A systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer risk

por Elands, Rachel J. J., Simons, Colinda C. J. M., Riemenschneider, Mona, Isaacs, Aaron, Schouten, Leo J., Verhage, Bas A., Van Steen, Kristel, Godschalk, Roger W. L., van den Brandt, Piet A., Stoll, Monika, Weijenberg, Matty P.
Publicado 2017

Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: The Erasmus Rucphen Family Study

por Isaacs, Aaron, Sayed-Tabatabaei, Fakhredin A., Aulchenko, Yurii S., Zillikens, M. Carola, Sijbrands, Eric J. G., Schut, Anna F. C., Rutten, Wim P. F., Pols, Huibert A. P., Witteman, Jacqueline C. M., Oostra, Ben A., van Duijn, Cornelia M.
Publicado 2007

A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study

por Silva, Claudia T., Zorkoltseva, Irina V., Amin, Najaf, Demirkan, Ayşe, van Leeuwen, Elisabeth M., Kors, Jan A., van den Berg, Marten, Stricker, Bruno H., Uitterlinden, André G., Kirichenko, Anatoly V., Witteman, Jacqueline C. M., Willemsen, Rob, Oostra, Ben A., Axenovich, Tatiana I., van Duijn, Cornelia M., Isaacs, Aaron
Publicado 2016

Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

por Ricaño-Ponce, Isis, Zhernakova, Daria V., Deelen, Patrick, Luo, Oscar, Li, Xingwang, Isaacs, Aaron, Karjalainen, Juha, Di Tommaso, Jennifer, Borek, Zuzanna Agnieszka, Zorro, Maria M., Gutierrez-Achury, Javier, Uitterlinden, Andre G., Hofman, Albert, van Meurs, Joyce, Netea, Mihai G., Jonkers, Iris H., Withoff, Sebo, van Duijn, Cornelia M., Li, Yang, Ruan, Yijun, Franke, Lude, Wijmenga, Cisca, Kumar, Vinod
Publicado 2016

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

por Silva, Claudia Tamar, Zorkoltseva, Irina V., Niemeijer, Maartje N., van den Berg, Marten E., Amin, Najaf, Demirkan, Ayşe, van Leeuwen, Elisa, Iglesias, Adriana I., Piñeros-Hernández, Laura B., Restrepo, Carlos M., Kors, Jan A., Kirichenko, Anatoly V., Willemsen, Rob, Oostra, Ben A., Stricker, Bruno H., Uitterlinden, André G., Axenovich, Tatiana I., van Duijn, Cornelia M., Isaacs, Aaron
Publicado 2018

A Genome-Wide Association Study of Optic Disc Parameters

por Ramdas, Wishal D., van Koolwijk, Leonieke M. E., Ikram, M. Kamran, Jansonius, Nomdo M., de Jong, Paulus T. V. M., Bergen, Arthur A. B., Isaacs, Aaron, Amin, Najaf, Aulchenko, Yurii S., Wolfs, Roger C. W., Hofman, Albert, Rivadeneira, Fernando, Oostra, Ben A., Uitterlinden, Andre G., Hysi, Pirro, Hammond, Christopher J., Lemij, Hans G., Vingerling, Johannes R., Klaver, Caroline C. W., van Duijn, Cornelia M.
Publicado 2010

A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level

por Pattaro, Cristian, De Grandi, Alessandro, Vitart, Veronique, Hayward, Caroline, Franke, Andre, Aulchenko, Yurii S, Johansson, Asa, Wild, Sarah H, Melville, Scott A, Isaacs, Aaron, Polasek, Ozren, Ellinghaus, David, Kolcic, Ivana, Nöthlings, Ute, Zgaga, Lina, Zemunik, Tatijana, Gnewuch, Carsten, Schreiber, Stefan, Campbell, Susan, Hastie, Nick, Boban, Mladen, Meitinger, Thomas, Oostra, Ben A, Riegler, Peter, Minelli, Cosetta, Wright, Alan F, Campbell, Harry, van Duijn, Cornelia M, Gyllensten, Ulf, Wilson, James F, Krawczak, Michael, Rudan, Igor, Pramstaller, Peter P
Publicado 2010

The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels

por van Leeuwen, Elisabeth M., Smouter, Françoise A. S., Kam-Thong, Tony, Karbalai, Nazanin, Smith, Albert V., Harris, Tamara B., Launer, Lenore J., Sitlani, Colleen M., Li, Guo, Brody, Jennifer A., Bis, Joshua C., White, Charles C., Jaiswal, Alok, Oostra, Ben A., Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, Andre G., Boerwinkle, Eric, Ballantyne, Christie M., Gudnason, Vilmundur, Psaty, Bruce M., Cupples, L. Adrienne, Järvelin, Marjo-Riitta, Ripatti, Samuli, Isaacs, Aaron, Müller-Myhsok, Bertram, Karssen, Lennart C., van Duijn, Cornelia M.
Publicado 2014

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

por Verweij, Niek, Mateo Leach, Irene, Isaacs, Aaron, Arking, Dan E., Bis, Joshua C., Pers, Tune H., Van Den Berg, Marten E., Lyytikäinen, Leo-Pekka, Barnett, Phil, Wang, Xinchen, Soliman, Elsayed Z., Van Duijn, Cornelia M., Kähönen, Mika, Van Veldhuisen, Dirk J., Kors, Jan A., Raitakari, Olli T., Silva, Claudia T., Lehtimäki, Terho, Hillege, Hans L., Hirschhorn, Joel N., Boyer, Laurie A., Van Gilst, Wiek H., Alonso, Alvaro, Sotoodehnia, Nona, Eijgelsheim, Mark, De Boer, Rudolf A., De Bakker, Paul I. W., Franke, Lude, Van Der Harst, Pim
Publicado 2016

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

por Hicks, Andrew A., Pramstaller, Peter P., Johansson, Åsa, Vitart, Veronique, Rudan, Igor, Ugocsai, Peter, Aulchenko, Yurii, Franklin, Christopher S., Liebisch, Gerhard, Erdmann, Jeanette, Jonasson, Inger, Zorkoltseva, Irina V., Pattaro, Cristian, Hayward, Caroline, Isaacs, Aaron, Hengstenberg, Christian, Campbell, Susan, Gnewuch, Carsten, Janssens, A. CecileJ.W., Kirichenko, Anatoly V., König, Inke R., Marroni, Fabio, Polasek, Ozren, Demirkan, Ayse, Kolcic, Ivana, Schwienbacher, Christine, Igl, Wilmar, Biloglav, Zrinka, Witteman, Jacqueline C. M., Pichler, Irene, Zaboli, Ghazal, Axenovich, Tatiana I., Peters, Annette, Schreiber, Stefan, Wichmann, H.-Erich, Schunkert, Heribert, Hastie, Nick, Oostra, Ben A., Wild, Sarah H., Meitinger, Thomas, Gyllensten, Ulf, van Duijn, Cornelia M., Wilson, James F., Wright, Alan, Schmitz, Gerd, Campbell, Harry
Publicado 2009

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

por van der Spek, Ashley, Broer, Linda, Draisma, Harmen H. M., Pool, René, Albrecht, Eva, Beekman, Marian, Mangino, Massimo, Raag, Mait, Nyholt, Dale R., Dharuri, Harish K., Codd, Veryan, Amin, Najaf, de Geus, Eco J. C., Deelen, Joris, Demirkan, Ayse, Yet, Idil, Fischer, Krista, Haller, Toomas, Henders, Anjali K., Isaacs, Aaron, Medland, Sarah E., Montgomery, Grant W., Mooijaart, Simon P., Strauch, Konstantin, Suchiman, H. Eka D., Vaarhorst, Anika A. M., van Heemst, Diana, Wang-Sattler, Rui, Whitfield, John B., Willemsen, Gonneke, Wright, Margaret J., Martin, Nicholas G., Samani, Nilesh J., Metspalu, Andres, Eline Slagboom, P., Spector, Tim D., Boomsma, Dorret I., van Duijn, Cornelia M., Gieger, Christian
Publicado 2019