Rapid Response Subunit Vaccine Design in the Absence of Structural Information

por Wijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel, Chappell, Keith J.
Publicado 2020

Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates

por Isaacs, Ariel, Cheung, Stacey T. M., Thakur, Nazia, Jaberolansar, Noushin, Young, Andrew, Modhiran, Naphak, Bailey, Dalan, Graham, Simon P., Young, Paul R., Chappell, Keith J., Watterson, Daniel
Publicado 2021

Adjuvant Selection for Influenza and RSV Prefusion Subunit Vaccines

por Isaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel, Chappell, Keith J.
Publicado 2021

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

por O’Donnell, Jake S., Isaacs, Ariel, Jakob, Virginie, Lebas, Celia, Barnes, James B., Reading, Patrick C., Young, Paul R., Watterson, Daniel, Dubois, Patrice M., Collin, Nicolas, Chappell, Keith J.
Publicado 2022

Structure and antigenicity of divergent Henipavirus fusion glycoproteins

por Isaacs, Ariel, Low, Yu Shang, Macauslane, Kyle L., Seitanidou, Joy, Pegg, Cassandra L., Cheung, Stacey T. M., Liang, Benjamin, Scott, Connor A. P., Landsberg, Michael J., Schulz, Benjamin L., Chappell, Keith J., Modhiran, Naphak, Watterson, Daniel
Publicado 2023

Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion

por Thakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P., Bailey, Dalan
Publicado 2020

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

por Pedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P., Donofrio, Gaetano
Publicado 2020

Nucleocapsid Specific Diagnostics for the Detection of Divergent SARS-CoV-2 Variants

por Isaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J., Watterson, Daniel
Publicado 2022

Monoclonal Antibodies Specific for SARS-CoV-2 Spike Protein Suitable for Multiple Applications for Current Variants of Concern

por Morgan, Mahali S., Yan, Kexin, Le, Thuy T., Johnston, Ryan A., Amarilla, Alberto A., Muller, David A., McMillan, Christopher L. D., Modhiran, Naphak, Watterson, Daniel, Potter, James R., Sng, Julian D.J., Lor, Mary, Paramitha, Devina, Isaacs, Ariel, Khromykh, Alexander A., Hall, Roy A., Suhrbier, Andreas, Rawle, Daniel J., Hobson-Peters, Jody
Publicado 2022

Dermal Delivery of a SARS-CoV-2 Subunit Vaccine Induces Immunogenicity against Variants of Concern

por McMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R., Muller, David A.
Publicado 2022

A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

por Xi, Cecy R, Di Fazio, Arianna, Nadvi, Naveed Ahmed, Patel, Karishma, Xiang, Michelle Sui Wen, Zhang, Hui Emma, Deshpande, Chandrika, Low, Jason K K, Wang, Xiaonan Trixie, Chen, Yiqian, McMillan, Christopher L D, Isaacs, Ariel, Osborne, Brenna, Vieira de Ribeiro, Ana Júlia, McCaughan, Geoffrey W, Mackay, Joel P, Church, W Bret, Gorrell, Mark D
Publicado 2020

Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine

por McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T. M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A. J., Muller, David A.
Publicado 2021

A platform technology for generating subunit vaccines against diverse viral pathogens

por Young, Andrew, Isaacs, Ariel, Scott, Connor A. P., Modhiran, Naphak, McMillan, Christopher L. D., Cheung, Stacey T. M., Barr, Jennifer, Marsh, Glenn, Thakur, Nazia, Bailey, Dalan, Li, Kenneth S. M., Luk, Hayes K. H., Kok, Kin-Hang, Lau, Susanna K. P., Woo, Patrick C. Y., Furuyama, Wakako, Marzi, Andrea, Young, Paul R., Chappell, Keith J., Watterson, Daniel
Publicado 2022

SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein

por Albornoz, Eduardo A., Amarilla, Alberto A., Modhiran, Naphak, Parker, Sandra, Li, Xaria X., Wijesundara, Danushka K., Aguado, Julio, Zamora, Adriana Pliego, McMillan, Christopher L. D., Liang, Benjamin, Peng, Nias Y. G., Sng, Julian D. J., Saima, Fatema Tuj, Fung, Jenny N., Lee, John D., Paramitha, Devina, Parry, Rhys, Avumegah, Michael S., Isaacs, Ariel, Lo, Martin W., Miranda-Chacon, Zaray, Bradshaw, Daniella, Salinas-Rebolledo, Constanza, Rajapakse, Niwanthi W., Wolvetang, Ernst J., Munro, Trent P., Rojas-Fernandez, Alejandro, Young, Paul R., Stacey, Katryn J., Khromykh, Alexander A., Chappell, Keith J., Watterson, Daniel, Woodruff, Trent M.
Publicado 2022

A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants

por Modhiran, Naphak, Lauer, Simon Malte, Amarilla, Alberto A., Hewins, Peter, Lopes van den Broek, Sara Irene, Low, Yu Shang, Thakur, Nazia, Liang, Benjamin, Nieto, Guillermo Valenzuela, Jung, James, Paramitha, Devina, Isaacs, Ariel, Sng, Julian D.J., Song, David, Jørgensen, Jesper Tranekjær, Cheuquemilla, Yorka, Bürger, Jörg, Andersen, Ida Vang, Himelreichs, Johanna, Jara, Ronald, MacLoughlin, Ronan, Miranda-Chacon, Zaray, Chana-Cuevas, Pedro, Kramer, Vasko, Spahn, Christian, Mielke, Thorsten, Khromykh, Alexander A., Munro, Trent, Jones, Martina L., Young, Paul R., Chappell, Keith, Bailey, Dalan, Kjaer, Andreas, Herth, Matthias Manfred, Jurado, Kellie Ann, Schwefel, David, Rojas-Fernandez, Alejandro, Watterson, Daniel
Publicado 2023

Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

por Watterson, Daniel, Wijesundara, Danushka K, Modhiran, Naphak, Mordant, Francesca L, Li, Zheyi, Avumegah, Michael S, McMillan, Christopher LD, Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey TM, Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L, Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam, Zhou, Qi, Brockman, David A, Morgan, Sherry J, Lau, Cora, Tran, Mai H, Tapley, Peter, Villalón‐Letelier, Fernando, Barnes, James, Young, Andrew, Jaberolansar, Noushin, Scott, Connor AP, Isaacs, Ariel, Amarilla, Alberto A, Khromykh, Alexander A, van den Brand, Judith MA, Reading, Patrick C, Ranasinghe, Charani, Subbarao, Kanta, Munro, Trent P, Young, Paul R, Chappell, Keith J
Publicado 2021