HER2 and HER3 cooperatively regulate cancer cell growth and determine sensitivity to the novel investigational EGFR/HER2 kinase inhibitor TAK-285

por Takagi, Shinji, Banno, Hiroshi, Hayashi, Akira, Tamura, Toshiya, Ishikawa, Tomoyasu, Ohta, Yoshikazu
Publicado 2014

Antitumor Activity of TAK-285, an Investigational, Non-Pgp Substrate HER2/EGFR Kinase Inhibitor, in Cultured Tumor Cells, Mouse and Rat Xenograft Tumors, and in an HER2-Positive Br...

por Nakayama, Akiko, Takagi, Shinji, Yusa, Tadashi, Yaguchi, Masahiro, Hayashi, Akira, Tamura, Toshiya, Kawakita, Youichi, Ishikawa, Tomoyasu, Ohta, Yoshikazu
Publicado 2013

Aneuploidy generates proteotoxic stress and DNA damage concurrently with p53-mediated post-mitotic apoptosis in SAC-impaired cells

por Ohashi, Akihiro, Ohori, Momoko, Iwai, Kenichi, Nakayama, Yusuke, Nambu, Tadahiro, Morishita, Daisuke, Kawamoto, Tomohiro, Miyamoto, Maki, Hirayama, Takaharu, Okaniwa, Masanori, Banno, Hiroshi, Ishikawa, Tomoyasu, Kandori, Hitoshi, Iwata, Kentaro
Publicado 2015