Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk

por Powell, Samuel K., O’Shea, Callan, Townsley, Kayla, Prytkova, Iya, Dobrindt, Kristina, Elahi, Rahat, Iskhakova, Marina, Lambert, Tova, Valada, Aditi, Liao, Will, Ho, Seok-Man, Slesinger, Paul A., Huckins, Laura M., Akbarian, Schahram, Brennand, Kristen J.
Publicado 2023

Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases

por Wei, Julong, Lambert, Tova Y., Valada, Aditi, Patel, Nikhil, Walker, Kellie, Lenders, Jayna, Schmidt, Carl J., Iskhakova, Marina, Alazizi, Adnan, Mair-Meijers, Henriette, Mash, Deborah C., Luca, Francesca, Pique-Regi, Roger, Bannon, Michael J, Akbarian, Schahram
Publicado 2023

Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder

por Wei, Julong, Lambert, Tova Y., Valada, Aditi, Patel, Nikhil, Walker, Kellie, Lenders, Jayna, Schmidt, Carl J., Iskhakova, Marina, Alazizi, Adnan, Mair-Meijers, Henriette, Mash, Deborah C., Luca, Francesca, Pique-Regi, Roger, Bannon, Michael J., Akbarian, Schahram
Publicado 2023

Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose

por Corradin, Olivia, Sallari, Richard, Hoang, An T., Kassim, Bibi S, Hutta, Gabriella Ben, Cuoto, Lizette, Quach, Bryan C., Lovrenert, Katreya, Hays, Cameron, Gryder, Berkley E., Iskhakova, Marina, Cates, Hannah, Song, Yanwei, Bartels, Cynthia F., Hancock, Dana B., Mash, Deborah C., Johnson, Eric O., Akbarian, Schahram, Scacheri, Peter C.
Publicado 2022

Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions

por Chandrasekaran, Sandhya, Espeso-Gil, Sergio, Loh, Yong-Hwee Eddie, Javidfar, Behnam, Kassim, Bibi, Zhu, Yueyan, Zhang, Yuan, Dong, Yuhao, Bicks, Lucy K., Li, Haixin, Rajarajan, Prashanth, Peter, Cyril J., Sun, Daijing, Agullo-Pascual, Esperanza, Iskhakova, Marina, Estill, Molly, Lesch, Bluma J., Shen, Li, Jiang, Yan, Akbarian, Schahram
Publicado 2021

Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection

por Dobrindt, Kristina, Hoagland, Daisy A., Seah, Carina, Kassim, Bibi, O’Shea, Callan P., Iskhakova, Marina, Fernando, Michael B., Deans, P.J. Michael, Powell, Samuel K., Javidfar, Ben, Murphy, Aleta, Peter, Cyril, Møeller, Rasmus, Garcia, Meilin Fernandez, Kimura, Masaki, Iwasawa, Kentaro, Crary, John, Kotton, Darrell N., Takebe, Takanori, Huckins, Laura M., tenOever, Benjamin R., Akbarian, Schahram, Brennand, Kristen J.
Publicado 2020

A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons

por Espeso-Gil, Sergio, Halene, Tobias, Bendl, Jaroslav, Kassim, Bibi, Ben Hutta, Gabriella, Iskhakova, Marina, Shokrian, Neda, Auluck, Pavan, Javidfar, Behnam, Rajarajan, Prashanth, Chandrasekaran, Sandhya, Peter, Cyril J., Cote, Alanna, Birnbaum, Rebecca, Liao, Will, Borrman, Tyler, Wiseman, Jennifer, Bell, Aaron, Bannon, Michael J., Roussos, Panagiotis, Crary, John F., Weng, Zhiping, Marenco, Stefano, Lipska, Barbara, Tsankova, Nadejda M., Huckins, Laura, Jiang, Yan, Akbarian, Schahram
Publicado 2020

Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection

por Dobrindt, Kristina, Hoagland, Daisy A., Seah, Carina, Kassim, Bibi, O'Shea, Callan P., Murphy, Aleta, Iskhakova, Marina, Fernando, Michael B., Powell, Samuel K., Deans, P.J. Michael, Javidfar, Ben, Peter, Cyril, Møller, Rasmus, Uhl, Skyler A., Garcia, Meilin Fernandez, Kimura, Masaki, Iwasawa, Kentaro, Crary, John F., Kotton, Darrell N., Takebe, Takanori, Huckins, Laura M., tenOever, Benjamin R., Akbarian, Schahram, Brennand, Kristen J.
Publicado 2021