Mistranslation-associated perturbations of proteostasis do not promote accumulation of amyloid beta and plaque deposition in aged mouse brain

por Santhosh Kumar, Harshitha, Moore, James, Steiner, Adrian C., Sotirakis, Emmanuel, Schärli, Benjamin, Isnard-Petit, Patricia, Thiam, Kader, Wolfer, David P., Böttger, Erik C.
Publicado 2023

Unexpected genomic rearrangements at targeted loci associated with CRISPR/Cas9-mediated knock-in

por Rezza, Amélie, Jacquet, Christelle, Le Pillouer, Amélie, Lafarguette, Florian, Ruptier, Charlotte, Billandon, Marion, Isnard Petit, Patricia, Trouttet, Séverine, Thiam, Kader, Fraichard, Alexandre, Chérifi, Yacine
Publicado 2019

Random errors in protein synthesis activate an age-dependent program of muscle atrophy in mice

por Moore, James, Akbergenov, Rashid, Nigri, Martina, Isnard-Petit, Patricia, Grimm, Amandine, Seebeck, Petra, Restelli, Lisa, Frank, Stephan, Eckert, Anne, Thiam, Kader, Wolfer, David P., Shcherbakov, Dimitri, Böttger, Erik C.
Publicado 2021

Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading

por Juskeviciene, Reda, Fritz, Ann-Kristina, Brilkova, Margarita, Akbergenov, Rashid, Schmitt, Karen, Rehrauer, Hubert, Laczko, Endre, Isnard-Petit, Patricia, Thiam, Kader, Eckert, Anne, Schacht, Jochen, Wolfer, David P., Böttger, Erik C., Shcherbakov, Dimitri
Publicado 2022

Mutant MRPS5 affects mitoribosomal accuracy and confers stress‐related behavioral alterations

por Akbergenov, Rashid, Duscha, Stefan, Fritz, Ann‐Kristina, Juskeviciene, Reda, Oishi, Naoki, Schmitt, Karen, Shcherbakov, Dimitri, Teo, Youjin, Boukari, Heithem, Freihofer, Pietro, Isnard‐Petit, Patricia, Oettinghaus, Björn, Frank, Stephan, Thiam, Kader, Rehrauer, Hubert, Westhof, Eric, Schacht, Jochen, Eckert, Anne, Wolfer, David, Böttger, Erik C
Publicado 2018