Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes

por Israel, Marc K, Istvan, Eva, Baron, Michelle A
Publicado 2008

Esterase mutation is a mechanism of resistance to antimalarial compounds

por Istvan, Eva S., Mallari, Jeremy P., Corey, Victoria C., Dharia, Neekesh V., Marshall, Garland R., Winzeler, Elizabeth A., Goldberg, Daniel E.
Publicado 2017

Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface

por Garten, Matthias, Beck, Josh R., Roth, Robyn, Tenkova-Heuser, Tatyana, Heuser, John, Istvan, Eva S., Bleck, Christopher K. E., Goldberg, Daniel E., Zimmerberg, Joshua
Publicado 2020

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

por Istvan, Eva S, Das, Sudipta, Bhatnagar, Suyash, Beck, Josh R, Owen, Edward, Llinas, Manuel, Ganesan, Suresh M, Niles, Jacquin C, Winzeler, Elizabeth, Vaidya, Akhil B, Goldberg, Daniel E
Publicado 2019

Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery

por Murithi, James M., Owen, Edward S., Istvan, Eva S., Lee, Marcus C.S., Ottilie, Sabine, Chibale, Kelly, Goldberg, Daniel E., Winzeler, Elizabeth A., Llinás, Manuel, Fidock, David A., Vanaerschot, Manu
Publicado 2020

PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

por Rocamora, Frances, Gupta, Purva, Istvan, Eva S., Luth, Madeline R., Carpenter, Emma F., Kümpornsin, Krittikorn, Sasaki, Erika, Calla, Jaeson, Mittal, Nimisha, Carolino, Krypton, Owen, Edward, Llinás, Manuel, Ottilie, Sabine, Goldberg, Daniel E., Lee, Marcus C. S., Winzeler, Elizabeth A.
Publicado 2021

Prioritization of Molecular Targets for Antimalarial Drug Discovery

por Forte, Barbara, Ottilie, Sabine, Plater, Andrew, Campo, Brice, Dechering, Koen J., Gamo, Francisco Javier, Goldberg, Daniel E., Istvan, Eva S., Lee, Marcus, Lukens, Amanda K., McNamara, Case W., Niles, Jacquin C., Okombo, John, Pasaje, Charisse Flerida A., Siegel, Miles G., Wirth, Dyann, Wyllie, Susan, Fidock, David A., Baragaña, Beatriz, Winzeler, Elizabeth A., Gilbert, Ian H.
Publicado 2021

MalDA, Accelerating Malaria Drug Discovery

por Yang, Tuo, Ottilie, Sabine, Istvan, Eva S., Godinez-Macias, Karla P., Lukens, Amanda K., Baragaña, Beatriz, Campo, Brice, Walpole, Chris, Niles, Jacquin C., Chibale, Kelly, Dechering, Koen J., Llinás, Manuel, Lee, Marcus C.S., Kato, Nobutaka, Wyllie, Susan, McNamara, Case W., Gamo, Francisco Javier, Burrows, Jeremy, Fidock, David A., Goldberg, Daniel E., Gilbert, Ian H., Wirth, Dyann F., Winzeler, Elizabeth A.
Publicado 2021

A broad analysis of resistance development in the malaria parasite

por Corey, Victoria C., Lukens, Amanda K., Istvan, Eva S., Lee, Marcus C. S., Franco, Virginia, Magistrado, Pamela, Coburn-Flynn, Olivia, Sakata-Kato, Tomoyo, Fuchs, Olivia, Gnädig, Nina F., Goldgof, Greg, Linares, Maria, Gomez-Lorenzo, Maria G., De Cózar, Cristina, Lafuente-Monasterio, Maria Jose, Prats, Sara, Meister, Stephan, Tanaseichuk, Olga, Wree, Melanie, Zhou, Yingyao, Willis, Paul A., Gamo, Francisco-Javier, Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Publicado 2016

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

por Reader, Janette, van der Watt, Mariëtte E., Taylor, Dale, Le Manach, Claire, Mittal, Nimisha, Ottilie, Sabine, Theron, Anjo, Moyo, Phanankosi, Erlank, Erica, Nardini, Luisa, Venter, Nelius, Lauterbach, Sonja, Bezuidenhout, Belinda, Horatscheck, Andre, van Heerden, Ashleigh, Spillman, Natalie J., Cowell, Anne N., Connacher, Jessica, Opperman, Daniel, Orchard, Lindsey M., Llinás, Manuel, Istvan, Eva S., Goldberg, Daniel E., Boyle, Grant A., Calvo, David, Mancama, Dalu, Coetzer, Theresa L., Winzeler, Elizabeth A., Duffy, James, Koekemoer, Lizette L., Basarab, Gregory, Chibale, Kelly, Birkholtz, Lyn-Marié
Publicado 2021

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

por Murithi, James M., Deni, Ioanna, Pasaje, Charisse Flerida A., Okombo, John, Bridgford, Jessica L., Gnädig, Nina F., Edwards, Rachel L., Yeo, Tomas, Mok, Sachel, Burkhard, Anna Y., Coburn-Flynn, Olivia, Istvan, Eva S., Sakata-Kato, Tomoyo, Gomez-Lorenzo, Maria G., Cowell, Annie N., Wicht, Kathryn J., Le Manach, Claire, Kalantarov, Gavreel F., Dey, Sumanta, Duffey, Maëlle, Laleu, Benoît, Lukens, Amanda K., Ottilie, Sabine, Vanaerschot, Manu, Trakht, Ilya N., Gamo, Francisco-Javier, Wirth, Dyann F., Goldberg, Daniel E., Odom John, Audrey R., Chibale, Kelly, Winzeler, Elizabeth A., Niles, Jacquin C., Fidock, David A.
Publicado 2022

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

por Cowell, Annie N., Istvan, Eva S., Lukens, Amanda K., Gomez-Lorenzo, Maria G., Vanaerschot, Manu, Sakata-Kato, Tomoyo, Flannery, Erika L., Magistrado, Pamela, Owen, Edward, Abraham, Matthew, LaMonte, Gregory, Painter, Heather J., Williams, Roy M., Franco, Virginia, Linares, Maria, Arriaga, Ignacio, Bopp, Selina, Corey, Victoria C., Gnädig, Nina F., Coburn-Flynn, Olivia, Reimer, Christin, Gupta, Purva, Murithi, James M., Moura, Pedro A., Fuchs, Olivia, Sasaki, Erika, Kim, Sang W., Teng, Christine H., Wang, Lawrence T., Akidil, Aslı, Adjalley, Sophie, Willis, Paul A., Siege, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Llinás, Manuel, Ottilie, Sabine, Gamo, Francisco-Javier, Lee, Marcus C. S., Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Publicado 2018

Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase

por Xie, Stanley C., Wang, Yinuo, Morton, Craig J., Metcalfe, Riley D., Dogovski, Con, Pasaje, Charisse Flerida A., Dunn, Elyse, Luth, Madeline R, Kumpornsin, Krittikorn, Istvan, Eva S, Park, Joon Sung, Fairhurst, Kate J., Ketprasit, Nutpakal, Yeo, Tomas, Yildirim, Okan, Bhebhe, Mathamsanqa N., Klug, Dana M., Rutledge, Peter J., Godoy, Luiz C., Dey, Sumanta, De Souza, Mariana Laureano, Siqueira-Neto, Jair L., Du, Yawei, Puhalovich, Tanya, Amini, Mona, Shami, Gerry, Loesbanluechai, Duangkamon, Nie, Shuai, Williamson, Nicholas, Jana, Gouranga P., Maity, Bikash C., Thomson, Patrick, Foley, Thomas, Tan, Derek S., Niles, Jacquin C, Han, Byung Woo, Goldberg, Daniel E, Burrows, Jeremy, Fidock, David A., Lee, Marcus C.S., Winzeler, Elizabeth A., Griffin, Michael D. W., Todd, Matthew H., Tilley, Leann
Publicado 2023