Discoidin domain receptors: Microenvironment sensors that promote cellular migration and invasion

por Itoh, Yoshifumi
Publicado 2018

Modulation of Microenvironment Signals by Proteolytic Shedding of Cell Surface Extracellular Matrix Receptors

por Itoh, Yoshifumi
Publicado 2021

Proteolytic modulation of tumor microenvironment signals during cancer progression

por Itoh, Yoshifumi
Publicado 2022

MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms

por Gifford, Valentina, Itoh, Yoshifumi
Publicado 2019

Alpha-2-Macroglobulin in Inflammation, Immunity and Infections

por Vandooren, Jennifer, Itoh, Yoshifumi
Publicado 2021

Cytoplasmic tail–dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity

por Uekita, Takamasa, Itoh, Yoshifumi, Yana, Ikuo, Ohno, Hiroshi, Seiki, Motoharu
Publicado 2001

Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts

por Majkowska, Iwona, Shitomi, Yasuyuki, Ito, Noriko, Gray, Nathanael S., Itoh, Yoshifumi
Publicado 2017

Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility

por Søgaard, Pia Pernille, Ito, Noriko, Sato, Nanami, Fujita, Yasuyuki, Matter, Karl, Itoh, Yoshifumi
Publicado 2019

Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

por Kajita, Masahiro, Itoh, Yoshifumi, Chiba, Tadashige, Mori, Hidetoshi, Okada, Akiko, Kinoh, Hiroaki, Seiki, Motoharu
Publicado 2001

ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1)

por Shitomi, Yasuyuki, Thøgersen, Ida B., Ito, Noriko, Leitinger, Birgit, Enghild, Jan J., Itoh, Yoshifumi
Publicado 2015

Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

por Kaneko, Kazuyo, Williams, Richard O., Dransfield, Daniel T., Nixon, Andrew E., Sandison, Ann, Itoh, Yoshifumi
Publicado 2016

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate

por Nandadasa, Sumeda, Martin, Daniel, Deshpande, Gauravi, Robert, Karyn L., Stack, M. Sharon, Itoh, Yoshifumi, Apte, Suneel S.
Publicado 2023

Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in...

por Gifford, Valentina, Woskowicz, Anna, Ito, Noriko, Balint, Stefan, Lagerholm, B. Christopher, Dustin, Michael L., Itoh, Yoshifumi
Publicado 2022

Inhibition of Shedding of Low‐Density Lipoprotein Receptor–Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis

por Yamamoto, Kazuhiro, Santamaria, Salvatore, Botkjaer, Kenneth A., Dudhia, Jayesh, Troeberg, Linda, Itoh, Yoshifumi, Murphy, Gillian, Nagase, Hideaki
Publicado 2017

Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix

por Weaver, Sarah A., Wolters, Brit, Ito, Noriko, Woskowicz, Anna M., Kaneko, Kazuyo, Shitomi, Yasuyuki, Seiki, Motoharu, Itoh, Yoshifumi
Publicado 2014

Gram-positive bacteria cell wall-derived lipoteichoic acid induces inflammatory alveolar bone loss through prostaglandin E production in osteoblasts

por Tominari, Tsukasa, Sanada, Ayumi, Ichimaru, Ryota, Matsumoto, Chiho, Hirata, Michiko, Itoh, Yoshifumi, Numabe, Yukihiro, Miyaura, Chisato, Inada, Masaki
Publicado 2021

Autofluorescence Lifetime Reports Cartilage Damage in Osteoarthritis

por Lagarto, João L., Nickdel, Mohammad B., Kelly, Douglas J., Price, Andrew, Nanchahal, Jagdeep, Dunsby, Chris, French, Paul, Itoh, Yoshifumi
Publicado 2020

A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology

por Tanaka, Ryo, Yoshinouchi, Shosei, Karouji, Kento, Tanaka, Yuki, Tominari, Tsukasa, Hirata, Michiko, Matsumoto, Chiho, Itoh, Yoshifumi, Miyaura, Chisato, Inada, Masaki
Publicado 2022

Hypergravity and microgravity exhibited reversal effects on the bone and muscle mass in mice

por Tominari, Tsukasa, Ichimaru, Ryota, Taniguchi, Keita, Yumoto, Akane, Shirakawa, Masaki, Matsumoto, Chiho, Watanabe, Kenta, Hirata, Michiko, Itoh, Yoshifumi, Shiba, Dai, Miyaura, Chisato, Inada, Masaki
Publicado 2019

Endosomal TLR3 signaling in stromal osteoblasts induces prostaglandin E(2)–mediated inflammatory periodontal bone resorption

por Tominari, Tsukasa, Akita, Miyuki, Matsumoto, Chiho, Hirata, Michiko, Yoshinouchi, Shosei, Tanaka, Yuki, Karouji, Kento, Itoh, Yoshifumi, Maruyama, Takayuki, Miyaura, Chisato, Numabe, Yukihiro, Inada, Masaki
Publicado 2022