Discovery and characterization of a small‐molecule enteropeptidase inhibitor, SCO‐792

por Sasaki, Masako, Miyahisa, Ikuo, Itono, Sachiko, Yashiro, Hiroaki, Hiyoshi, Hideyuki, Tsuchimori, Kazue, Hamagami, Ken‐ichi, Moritoh, Yusuke, Watanabe, Masanori, Tohyama, Kimio, Sasaki, Minoru, Sakamoto, Jun‐ichi, Kawamoto, Tomohiro
Publicado 2019

Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obes...

por Ikeda, Zenichi, Kakegawa, Keiko, Kikuchi, Fumiaki, Itono, Sachiko, Oki, Hideyuki, Yashiro, Hiroaki, Hiyoshi, Hideyuki, Tsuchimori, Kazue, Hamagami, Kenichi, Watanabe, Masanori, Sasaki, Masako, Ishihara, Youko, Tohyama, Kimio, Kitazaki, Tomoyuki, Maekawa, Tsuyoshi, Sasaki, Minoru
Publicado 2022

Collaborative virtual screening to elaborate an imidazo[1,2-a]pyridine hit series for visceral leishmaniasis

por Akao, Yuichiro, Canan, Stacie, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Itono, Sachiko, Kaki, Rina, Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Nakai, Hiromi, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shimada, Mitsuyuki, Shum, David, Watanabe, Nao-aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin
Publicado 2021

Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection

por Tawaraishi, Taisuke, Ochida, Atsuko, Akao, Yuichiro, Itono, Sachiko, Kamaura, Masahiro, Akther, Thamina, Shimada, Mitsuyuki, Canan, Stacie, Chowdhury, Sanjoy, Cao, Yafeng, Condroski, Kevin, Engkvist, Ola, Francisco, Amanda, Ghosh, Sunil, Kaki, Rina, Kelly, John M., Kimura, Chiaki, Kogej, Thierry, Nagaoka, Kazuya, Naito, Akira, Pairaudeau, Garry, Radu, Constantin, Roberts, Ieuan, Shum, David, Watanabe, Nao-aki, Xie, Huanxu, Yonezawa, Shuji, Yoshida, Osamu, Yoshida, Ryu, Mowbray, Charles, Perry, Benjamin
Publicado 2023