Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster

por Ivanov, Dobril K., Papatheodorou, Irene, Ziehm, Matthias, Thornton, Janet M.
Publicado 2013

SurvCurv database and online survival analysis platform update

por Ziehm, Matthias, Ivanov, Dobril K., Bhat, Aditi, Partridge, Linda, Thornton, Janet M.
Publicado 2015

Drug repurposing for aging research using model organisms

por Ziehm, Matthias, Kaur, Satwant, Ivanov, Dobril K., Ballester, Pedro J., Marcus, David, Partridge, Linda, Thornton, Janet M.
Publicado 2017

A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data

por Ivanov, Dobril K., Bostelmann, Gerrit, Lan-Leung, Benoit, Williams, Julie, Partridge, Linda, Escott-Price, Valentina, Thornton, Janet M.
Publicado 2020

Longevity GWAS Using the Drosophila Genetic Reference Panel

por Ivanov, Dobril K., Escott-Price, Valentina, Ziehm, Matthias, Magwire, Michael M., Mackay, Trudy F. C., Partridge, Linda, Thornton, Janet M.
Publicado 2015

Machine learning for the life-time risk prediction of Alzheimer’s disease: a systematic review

por Rowe, Thomas W, Katzourou, Ioanna K, Stevenson-Hoare, Joshua O, Bracher-Smith, Matthew R, Ivanov, Dobril K, Escott-Price, Valentina
Publicado 2021

Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity

por Niccoli, Teresa, Kerr, Fiona, Snoeren, Inge, Fabian, Daniel, Aleyakpo, Benjamin, Ivanov, Dobril, Sofola-Adesakin, Oyinkan, Cryar, Adam, Adcott, Jennifer, Thornton, Janet, Partridge, Linda
Publicado 2021

Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

por Bolukbasi, Ekin, Khericha, Mobina, Regan, Jennifer C., Ivanov, Dobril K., Adcott, Jennifer, Dyson, Miranda C., Nespital, Tobias, Thornton, Janet M., Alic, Nazif, Partridge, Linda
Publicado 2017

Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer’s disease through polygenic risk and RNA sequencing

por Crawford, Karen, Leonenko, Ganna, Baker, Emily, Grozeva, Detelina, Lan-Leung, Benoit, Holmans, Peter, Williams, Julie, O’Donovan, Michael C., Escott-Price, Valentina, Ivanov, Dobril K.
Publicado 2022

Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system

por Bolukbasi, Ekin, Woodling, Nathaniel S., Ivanov, Dobril K., Adcott, Jennifer, Foley, Andrea, Rajasingam, Arjunan, Gittings, Lauren M., Aleyakpo, Benjamin, Niccoli, Teresa, Thornton, Janet M., Partridge, Linda
Publicado 2021

No evidence for association between polymorphisms in GRM3 and schizophrenia

por Norton, Nadine, Williams, Hywel J, Dwyer, Sarah, Ivanov, Dobril, Preece, Anna C, Gerrish, Amy, Williams, Nigel M, Yerassimou, Pamela, Zammit, Stanley, O'Donovan, Michael C, Owen, Michael J
Publicado 2005

Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis

por Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana, Partridge, Linda
Publicado 2016

A genome-wide study shows a limited contribution of rare copy number variants to Alzheimer's disease risk

por Chapman, Jade, Rees, Elliott, Harold, Denise, Ivanov, Dobril, Gerrish, Amy, Sims, Rebecca, Hollingworth, Paul, Stretton, Alexandra, Holmans, Peter, Owen, Michael J., O'Donovan, Michael C., Williams, Julie, Kirov, George
Publicado 2013

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

por Kerr, Fiona, Sofola-Adesakin, Oyinkan, Ivanov, Dobril K., Gatliff, Jemma, Gomez Perez-Nievas, Beatriz, Bertrand, Hélène C., Martinez, Pedro, Callard, Rebecca, Snoeren, Inge, Cochemé, Helena M., Adcott, Jennifer, Khericha, Mobina, Castillo-Quan, Jorge Iván, Wells, Geoffrey, Noble, Wendy, Thornton, Janet, Partridge, Linda
Publicado 2017

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer’s disease

por Baker, Emily, Sims, Rebecca, Leonenko, Ganna, Frizzati, Aura, Harwood, Janet C., Grozeva, Detelina, Morgan, Kevin, Passmore, Peter, Holmes, Clive, Powell, John, Brayne, Carol, Gill, Michael, Mead, Simon, Bossù, Paola, Spalletta, Gianfranco, Goate, Alison M., Cruchaga, Carlos, Maier, Wolfgang, Heun, Reinhard, Jessen, Frank, Peters, Oliver, Dichgans, Martin, FröLich, Lutz, Ramirez, Alfredo, Jones, Lesley, Hardy, John, Ivanov, Dobril, Hill, Matthew, Holmans, Peter, Allen, Nicholas D., Morgan, B. Paul, Seshadri, Sudha, Schellenberg, Gerard D., Amouyel, Philippe, Williams, Julie, Escott-Price, Valentina
Publicado 2019

Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

por Jones, Lesley, Holmans, Peter A., Hamshere, Marian L., Harold, Denise, Moskvina, Valentina, Ivanov, Dobril, Pocklington, Andrew, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Pahwa, Jaspreet Singh, Jones, Nicola, Stretton, Alexandra, Morgan, Angharad R., Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Peters, Oliver, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panos, Al-Chalabi, Ammar, Shaw, Christopher E., Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H.-Erich, Rüther, Eckhard, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Hardy, John, O'Donovan, Michael C., Owen, Michael J., Williams, Julie
Publicado 2010

Correction: Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

por Jones, Lesley, Holmans, Peter A., Hamshere, Marian L., Harold, Denise, Moskvina, Valentina, Ivanov, Dobril, Pocklington, Andrew, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Pahwa, Jaspreet Singh, Jones, Nicola, Stretton, Alexandra, Morgan, Angharad R., Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K., Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S., Passmore, Peter A., Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Peters, Oliver, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M., Kauwe, John S. K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panos, Al-Chalabi, Ammar, Shaw, Christopher E., Singleton, Andrew B., Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H.-Erich, Rüther, Eckhard, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Hardy, John, O'Donovan, Michael C., Owen, Michael J., Williams, Julie
Publicado 2011

Common variants in ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer’s disease

por Hollingworth, Paul, Harold, Denise, Sims, Rebecca, Gerrish, Amy, Lambert, Jean-Charles, Carrasquillo, Minerva M, Abraham, Richard, Hamshere, Marian L, Pahwa, Jaspreet Singh, Moskvina, Valentina, Dowzell, Kimberley, Jones, Nicola, Stretton, Alexandra, Thomas, Charlene, Richards, Alex, Ivanov, Dobril, Widdowson, Caroline, Chapman, Jade, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K, Brayne, Carol, Rubinsztein, David C, Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Brown, Kristelle S, Passmore, Peter A, Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A David, Beaumont, Helen, Warden, Donald, Wilcock, Gordon, Love, Seth, Kehoe, Patrick G, Hooper, Nigel M, Vardy, Emma R. L. C., Hardy, John, Mead, Simon, Fox, Nick C, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, Rüther, Eckart, Heun, Reiner, Kölsch, Heike, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Gallacher, John, Rujescu, Dan, Giegling, Ina, Goate, Alison M, Kauwe, John S K, Cruchaga, Carlos, Nowotny, Petra, Morris, John C, Mayo, Kevin, Sleegers, Kristel, Bettens, Karolien, Engelborghs, Sebastiaan, De Deyn, Peter P, Van Broeckhoven, Christine, Livingston, Gill, Bass, Nicholas J, Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E, Tsolaki, Magda, Singleton, Andrew B, Guerreiro, Rita, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Pankratz, V Shane, Sando, Sigrid B, Aasly, Jan O, Barcikowska, Maria, Wszolek, Zbigniew K, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, van Duijn, Cornelia M, Breteler, Monique MB, Ikram, M Arfan, DeStefano, Anita L, Fitzpatrick, Annette L, Lopez, Oscar, Launer, Lenore J, Seshadri, Sudha, Berr, Claudine, Campion, Dominique, Epelbaum, Jacques, Dartigues, Jean-François, Tzourio, Christophe, Alpérovitch, Annick, Lathrop, Mark, Feulner, Thomas M, Friedrich, Patricia, Riehle, Caterina, Krawczak, Michael, Schreiber, Stefan, Mayhaus, Manuel, Nicolhaus, S, Wagenpfeil, Stefan, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Snædal, Jon, Björnsson, Sigurbjörn, Jonsson, Palmi V., Chouraki, Vincent, Genier-Boley, Benjamin, Hiltunen, Mikko, Soininen, Hilkka, Combarros, Onofre, Zelenika, Diana, Delepine, Marc, Bullido, Maria J, Pasquier, Florence, Mateo, Ignacio, Frank-Garcia, Ana, Porcellini, Elisa, Hanon, Olivier, Coto, Eliecer, Alvarez, Victoria, Bosco, Paolo, Siciliano, Gabriele, Mancuso, Michelangelo, Panza, Francesco, Solfrizzi, Vincenzo, Nacmias, Benedetta, Sorbi, Sandro, Bossù, Paola, Piccardi, Paola, Arosio, Beatrice, Annoni, Giorgio, Seripa, Davide, Pilotto, Alberto, Scarpini, Elio, Galimberti, Daniela, Brice, Alexis, Hannequin, Didier, Licastro, Federico, Jones, Lesley, Holmans, Peter A, Jonsson, Thorlakur, Riemenschneider, Matthias, Morgan, Kevin, Younkin, Steven G, Owen, Michael J, O’Donovan, Michael, Amouyel, Philippe, Williams, Julie
Publicado 2011