Preclinical disposition of MGS0274 besylate, a prodrug of a potent group II metabotropic glutamate receptor agonist MGS0008 for the treatment of schizophrenia

por Kinoshita, Kohnosuke, Ochi, Motoki, Iwata, Katsuya, Fukasawa, Misako, Yamaguchi, Jun‐ichi
Publicado 2019

Ozoralizumab, a Humanized Anti-TNFα NANOBODY(®) Compound, Exhibits Efficacy Not Only at the Onset of Arthritis in a Human TNF Transgenic Mouse but Also During Secondary Failure of...

por Ishiwatari-Ogata, Chihiro, Kyuuma, Masanao, Ogata, Hitoshi, Yamakawa, Machi, Iwata, Katsuya, Ochi, Motoki, Hori, Miyuki, Miyata, Noriyuki, Fujii, Yasuyuki
Publicado 2022

A novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis

por Oyama, Shohei, Ebina, Kosuke, Etani, Yuki, Hirao, Makoto, Kyuuma, Masanao, Fujii, Yasuyuki, Iwata, Katsuya, Ogawa, Bunichiro, Hasegawa, Tomoya, Kawano, Sasagu, Nakanishi, Yutaka, Okada, Seiji, Nakata, Ken
Publicado 2022