IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level

por Iwawaki, Takao, Akai, Ryoko, Kohno, Kenji
Publicado 2010

Identification of a consensus element recognized and cleaved by IRE1α

por Oikawa, Daisuke, Tokuda, Mio, Hosoda, Akira, Iwawaki, Takao
Publicado 2010

A transgenic mouse model for monitoring oxidative stress

por Oikawa, Daisuke, Akai, Ryoko, Tokuda, Mio, Iwawaki, Takao
Publicado 2012

Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β

por Oikawa, Daisuke, Kitamura, Akira, Kinjo, Masataka, Iwawaki, Takao
Publicado 2012

Transgenic mouse model exhibiting weak red fluorescence before and strong green fluorescence after Cre/loxP-mediated recombination

por Akai, Ryoko, Saito, Michiko, Kohno, Kenji, Iwawaki, Takao
Publicado 2020

Ablation of the Chaperone Protein ERdj5 Results in a Sjögren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients

por Apostolou, Eirini, Moustardas, Petros, Iwawaki, Takao, Tzioufas, Athanasios G., Spyrou, Giannis
Publicado 2019

Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy

por Kaufman, Daniel Robert, Papillon, Joan, Larose, Louise, Iwawaki, Takao, Cybulsky, Andrey V.
Publicado 2017

Transgenic mouse model for imaging of ATF4 translational activation-related cellular stress responses in vivo

por Iwawaki, Takao, Akai, Ryoko, Toyoshima, Takae, Takeda, Naoki, Ishikawa, Tomo-o, Yamamura, Ken-ichi
Publicado 2017

The Unfolded Protein Response Sensor IRE1 Regulates Activation of In Vitro Differentiated Type 1 Conventional DCs with Viral Stimuli

por Medel, Bernardita, Bernales, José Ignacio, Lira, Alonso, Fernández, Dominique, Iwawaki, Takao, Vargas, Pablo, Osorio, Fabiola
Publicado 2023

The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism

por Roy, Anirban, Tomaz da Silva, Meiricris, Bhat, Raksha, Bohnert, Kyle R, Iwawaki, Takao, Kumar, Ashok
Publicado 2021

Role of IRE1α in podocyte proteostasis and mitochondrial health

por Navarro-Betancourt, José R., Papillon, Joan, Guillemette, Julie, Iwawaki, Takao, Chung, Chen-Fang, Cybulsky, Andrey V.
Publicado 2020

Alterations in UPR Signaling by Methylmercury Trigger Neuronal Cell Death in the Mouse Brain

por Nomura, Ryosuke, Takasugi, Nobumasa, Hiraoka, Hideki, Iijima, Yuta, Iwawaki, Takao, Kumagai, Yoshito, Fujimura, Masatake, Uehara, Takashi
Publicado 2022

IRE1–XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells

por Tsuchiya, Yuichi, Saito, Michiko, Kadokura, Hiroshi, Miyazaki, Jun-ichi, Tashiro, Fumi, Imagawa, Yusuke, Iwawaki, Takao, Kohno, Kenji
Publicado 2018

Correction: IRE1–XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells

por Tsuchiya, Yuichi, Saito, Michiko, Kadokura, Hiroshi, Miyazaki, Jun-ichi, Tashiro, Fumi, Imagawa, Yusuke, Iwawaki, Takao, Kohno, Kenji
Publicado 2019

Salmonella Exhibit Altered Cellular Localization in the Presence of HLA-B27 and Codistribute with Endo-Reticular Membrane

por Kriston-Vizi, Janos, Lenart, Izabela, Iwawaki, Takao, Gould, Keith, Nesbeth, Darren, Powis, Simon J., Antoniou, Antony N.
Publicado 2022

Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration

por Massoudi, Dawiyat, Gorman, Seán, Kuo, Yien-Ming, Iwawaki, Takao, Oakes, Scott A., Papa, Feroz R., Gould, Douglas B.
Publicado 2023

IRE1α Promotes Zika Virus Infection via XBP1

por Kolpikova, Elena P., Tronco, Ana R., Den Hartigh, Andreas B., Jackson, Konner J., Iwawaki, Takao, Fink, Susan L.
Publicado 2020

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

por Athanasiou, Dimitra, Bevilacqua, Dalila, Aguila, Monica, McCulley, Caroline, Kanuga, Naheed, Iwawaki, Takao, Paul Chapple, J., Cheetham, Michael E.
Publicado 2014

Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress

por Nakato, Ryosuke, Ohkubo, Yu, Konishi, Akari, Shibata, Mari, Kaneko, Yuki, Iwawaki, Takao, Nakamura, Tomohiro, Lipton, Stuart A., Uehara, Takashi
Publicado 2015

Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity

por Forootan, Shiva S., Mutter, Fiona E., Kipar, Anja, Iwawaki, Takao, Francis, Ben, Goldring, Christopher E., Park, B. Kevin, Copple, Ian M.
Publicado 2017