Drug Metabolism and Pharmacokinetics of Antisense Oligonucleotide Therapeutics: Typical Profiles, Evaluation Approaches, and Points to Consider Compared with Small Molecule Drugs

por Takakusa, Hideo, Iwazaki, Norihiko, Nishikawa, Makiya, Yoshida, Tokuyuki, Obika, Satoshi, Inoue, Takao
Publicado 2023

Epigenetic Reprogramming of Human Hepatoma Cells: A Low-Cost Option for Drug Metabolism Assessment

por Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hagiwara, Keitaro, Iwazaki, Norihiko, Yamada, Yasuhiro, Hatada, Izuho, Ochiya, Takahiro
Publicado 2017

Prediction of human pharmacokinetics for low‐clearance compounds using pharmacokinetic data from chimeric mice with humanized livers

por Yoshida, Kosuke, Doi, Yuki, Iwazaki, Norihiko, Yasuhara, Hidenori, Ikenaga, Yuka, Shimizu, Hidetoshi, Nakada, Tomohisa, Watanabe, Tomoko, Tateno, Chise, Sanoh, Seigo, Kotake, Yaichiro
Publicado 2021