Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis

por Dizman, Nazli, Lyou, Yung, Salgia, Nicholas, Bergerot, Paulo Gustavo, Hsu, JoAnn, Enriquez, Daniel, Izatt, Tyler, Trent, Jeffrey M, Byron, Sara, Pal, Sumanta
Publicado 2020

Paired Tumor and Normal Whole Genome Sequencing of Metastatic Olfactory Neuroblastoma

por Weiss, Glen J., Liang, Winnie S., Izatt, Tyler, Arora, Shilpi, Cherni, Irene, Raju, Robert N., Hostetter, Galen, Kurdoglu, Ahmet, Christoforides, Alexis, Sinari, Shripad, Baker, Angela S., Metpally, Raghu, Tembe, Waibhav D., Phillips, Lori, Von Hoff, Daniel D., Craig, David W., Carpten, John D.
Publicado 2012

Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer

por Shanmugam, Vijayalakshmi, Ramanathan, Ramesh K, Lavender, Nicole A, Sinari, Shripad, Chadha, Manpreet, Liang, Winnie S, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Benson, Hollie, Phillips, Lori, Baker, Angela, Murray, Christopher, Hostetter, Galen, Von Hoff, Daniel D, Craig, David W, Carpten, John D
Publicado 2014

Personalized treatment of Sézary syndrome by targeting a novel CTLA4:CD28 fusion

por Sekulic, Aleksandar, Liang, Winnie S, Tembe, Waibhav, Izatt, Tyler, Kruglyak, Semyon, Kiefer, Jeffrey A, Cuyugan, Lori, Zismann, Victoria, Legendre, Christophe, Pittelkow, Mark R, Gohmann, John J, De Castro, Fernando R, Trent, Jeffrey, Carpten, John, Craig, David W, McDaniel, Timothy K
Publicado 2015

Cancer of the ampulla of Vater: analysis of the whole genome sequence exposes a potential therapeutic vulnerability

por Demeure, Michael J, Craig, David W, Sinari, Shripad, Moses, Tracy M, Christoforides, Alexis, Dinh, Jennifer, Izatt, Tyler, Aldrich, Jessica, Decker, Ardis, Baker, Angela, Cherni, Irene, Watanabe, April, Koep, Lawrence, Lake, Douglas, Hostetter, Galen, Trent, Jeffrey M, Von Hoff, Daniel D, Carpten, John D
Publicado 2012

A Pilot Study Using Next-Generation Sequencing in Advanced Cancers: Feasibility and Challenges

por Weiss, Glen J., Liang, Winnie S., Demeure, Michael J., Kiefer, Jeff A., Hostetter, Galen, Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Phillips, Lori, Benson, Hollie, Reiman, Rebecca, Baker, Angela, Marsh, Vickie, Von Hoff, Daniel D., Carpten, John D., Craig, David W.
Publicado 2013

Simultaneous Characterization of Somatic Events and HPV-18 Integration in a Metastatic Cervical Carcinoma Patient Using DNA and RNA Sequencing

por Liang, Winnie S., Aldrich, Jessica, Nasser, Sara, Kurdoglu, Ahmet, Phillips, Lori, Reiman, Rebecca, McDonald, Jacquelyn, Izatt, Tyler, Christoforides, Alexis, Baker, Angela, Craig, Christine, Egan, Jan B., Chase, Dana M., Farley, John H., Bryce, Alan H., Stewart, A. Keith, Borad, Mitesh J., Carpten, John D., Craig, David W., Monk, Bradley J.
Publicado 2014

Genome-Wide Characterization of Pancreatic Adenocarcinoma Patients Using Next Generation Sequencing

por Liang, Winnie S., Craig, David W., Carpten, John, Borad, Mitesh J., Demeure, Michael J., Weiss, Glen J., Izatt, Tyler, Sinari, Shripad, Christoforides, Alexis, Aldrich, Jessica, Kurdoglu, Ahmet, Barrett, Michael, Phillips, Lori, Benson, Hollie, Tembe, Waibhav, Braggio, Esteban, Kiefer, Jeffrey A., Legendre, Christophe, Posner, Richard, Hostetter, Galen H., Baker, Angela, Egan, Jan B., Han, Haiyong, Lake, Douglas, Stites, Edward C., Ramanathan, Ramesh K., Fonseca, Rafael, Stewart, A. Keith, Von Hoff, Daniel
Publicado 2012

Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment Wit...

por Bryce, Alan H., Borad, Mitesh J., Egan, Jan B., Condjella, Rachel M., Liang, Winnie S., Fonseca, Rafael, McCullough, Ann E., Hunt, Katherine S., Ritacca, Nicole R., Barrett, Michael T., Patel, Maitray D., Young, Scott W., Silva, Alvin C., Ho, Thai H., Halfdanarson, Thorvardur R., Stanton, Melissa L., Cheville, John, Swanson, Scott, Schneider, Daniel E., McWilliams, Robert R., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Cuyugan, Lori, McDonald, Jacquelyn, Adkins, Jonathan, Mastrian, Stephen D., Von Hoff, Daniel D., Craig, David W., Stewart, A. Keith, Carpten, John D.
Publicado 2016

Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers

por Borad, Mitesh J., Egan, Jan B., Condjella, Rachel M., Liang, Winnie S., Fonseca, Rafael, Ritacca, Nicole R., McCullough, Ann E., Barrett, Michael T., Hunt, Katherine S., Champion, Mia D., Patel, Maitray D., Young, Scott W., Silva, Alvin C., Ho, Thai H., Halfdanarson, Thorvardur R., McWilliams, Robert R., Lazaridis, Konstantinos N., Ramanathan, Ramesh K., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Cuyugan, Lori, McDonald, Jacquelyn, Adkins, Jonathan, Mastrian, Stephen D., Valdez, Riccardo, Jaroszewski, Dawn E., Von Hoff, Daniel D., Craig, David W., Stewart, A. Keith, Carpten, John D., Bryce, Alan H.
Publicado 2016

Identifying treatment options for BRAF(V600) wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial

por LoRusso, Patricia M., Sekulic, Aleksandar, Sosman, Jeffrey A., Liang, Winnie S., Carpten, John, Craig, David W., Solit, David B., Bryce, Alan H., Kiefer, Jeffrey A., Aldrich, Jessica, Nasser, Sara, Halperin, Rebecca, Byron, Sara A., Pilat, Mary Jo, Boerner, Scott A., Durecki, Diane, Hendricks, William P. D., Enriquez, Daniel, Izatt, Tyler, Keats, Jonathan, Legendre, Christophe, Markovic, Svetomir N., Weise, Amy, Naveed, Fatima, Schmidt, Jessica, Basu, Gargi D., Sekar, Shobana, Adkins, Jonathan, Tassone, Erica, Sivaprakasam, Karthigayini, Zismann, Victoria, Calvert, Valerie S., Petricoin, Emanuel F., Fecher, Leslie Anne, Lao, Christopher, Eder, J. Paul, Vogelzang, Nicholas J., Perlmutter, Jane, Gorman, Mark, Manica, Barbara, Fox, Lisa, Schork, Nicholas, Zelterman, Daniel, DeVeaux, Michelle, Joseph, Richard W., Cowey, C. Lance, Trent, Jeffrey M.
Publicado 2021

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

por Borad, Mitesh J., Champion, Mia D., Egan, Jan B., Liang, Winnie S., Fonseca, Rafael, Bryce, Alan H., McCullough, Ann E., Barrett, Michael T., Hunt, Katherine, Patel, Maitray D., Young, Scott W., Collins, Joseph M., Silva, Alvin C., Condjella, Rachel M., Block, Matthew, McWilliams, Robert R., Lazaridis, Konstantinos N., Klee, Eric W., Bible, Keith C., Harris, Pamela, Oliver, Gavin R., Bhavsar, Jaysheel D., Nair, Asha A., Middha, Sumit, Asmann, Yan, Kocher, Jean-Pierre, Schahl, Kimberly, Kipp, Benjamin R., Barr Fritcher, Emily G., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Phillips, Lori, McDonald, Jackie, Adkins, Jonathan, Mastrian, Stephen D., Placek, Pamela, Watanabe, Aprill T., LoBello, Janine, Han, Haiyong, Von Hoff, Daniel, Craig, David W., Stewart, A. Keith, Carpten, John D.
Publicado 2014