DIPG-40. Combined pharmacological and genetic screening to identify dependencies and combinations in ACVR1-mutant diffuse midline glioma

por Rogers, Rebecca, Carvalho, Diana, Grabovska, Yura, Fernandez, Elisabet, Izquierdo, Elisa, Mackay, Alan, Jones, Chris
Publicado 2022

A Comparison of EGFR Mutation Testing Methods in Lung Carcinoma: Direct Sequencing, Real-time PCR and Immunohistochemistry

por Angulo, Bárbara, Conde, Esther, Suárez-Gauthier, Ana, Plaza, Carlos, Martínez, Rebeca, Redondo, Pilar, Izquierdo, Elisa, Rubio-Viqueira, Belén, Paz-Ares, Luis, Hidalgo, Manuel, López-Ríos, Fernando
Publicado 2012

MODL-19. DIPG HARBOUR ALTERATIONS TARGETABLE BY MEK INHIBITORS, WITH ACQUIRED RESISTANCE MECHANISMS OVERCOME BY COMBINATORIAL UP- OR DOWN-STREAM INHIBITION

por Izquierdo, Elisa, Carvalho, Diana, Mackay, Alan, Temelso, Sara, Boult, Jessica K R, Molinari, Valeria, Stubbs, Mark, Depani, Sarita, O’Hare, Patricia, Robinson, Simon P, Hubank, Michael, Hargrave, Darren, Jones, Chris
Publicado 2020

The ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion

por Burford, Anna, Mackay, Alan, Popov, Sergey, Vinci, Maria, Carvalho, Diana, Clarke, Matthew, Izquierdo, Elisa, Avery, Aimee, Jacques, Thomas S., Ingram, Wendy J., Moore, Andrew S., Frawley, Kieran, Hassall, Timothy E., Robertson, Thomas, Jones, Chris
Publicado 2018

HGG-42. Evolutionary selection of key oncogenic alterations in patient-derived models of paediatric diffuse high grade glioma (PDHGG) subtypesin vitro andin vivo

por Mackay, Alan, Temelso, Sara, Carvalho, Diana, Kessler, Ketty, Boult, Jessica, Izquierdo, Elisa, Pereira, Rita, Potente, Elisabet Fernandez, Burford, Anna, Molinari, Valeria, Bjerke, Lynn, Grabovska, Yura, Rogers, Rebecca, Crampsie, Shauna, Das, Molina, Robinson, Simon, Clarke, Matthew, Jones, Chris
Publicado 2022

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

por Izquierdo, Elisa, Proszek, Paula, Pericoli, Giulia, Temelso, Sara, Clarke, Matthew, Carvalho, Diana M, Mackay, Alan, Marshall, Lynley V, Carceller, Fernando, Hargrave, Darren, Lannering, Birgitta, Pavelka, Zdenek, Bailey, Simon, Entz-Werle, Natacha, Grill, Jacques, Vassal, Gilles, Rodriguez, Daniel, Morgan, Paul S, Jaspan, Tim, Mastronuzzi, Angela, Vinci, Mara, Hubank, Michael, Jones, Chris
Publicado 2021

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

por Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris
Publicado 2020

FGF7–FGFR2 autocrine signaling increases growth and chemoresistance of fusion‐positive rhabdomyosarcomas

por Milton, Christopher I., Selfe, Joanna, Aladowicz, Ewa, Man, Stella Y. K., Bernauer, Carolina, Missiaglia, Edoardo, Walters, Zoë S., Gatz, Susanne A., Kelsey, Anna, Generali, Melanie, Box, Gary, Valenti, Melanie, de Haven‐Brandon, Alexis, Galiwango, David, Hayes, Angela, Clarke, Matthew, Izquierdo, Elisa, Gonzalez De Castro, David, Raynaud, Florence I., Kirkin, Vladimir, Shipley, Janet M.
Publicado 2021

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

por Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez
Publicado 2017

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

por Mackay, Alan, Burford, Anna, Molinari, Valeria, Jones, David T.W., Izquierdo, Elisa, Brouwer-Visser, Jurriaan, Giangaspero, Felice, Haberler, Christine, Pietsch, Torsten, Jacques, Thomas S., Figarella-Branger, Dominique, Rodriguez, Daniel, Morgan, Paul S., Raman, Pichai, Waanders, Angela J., Resnick, Adam C., Massimino, Maura, Garrè, Maria Luisa, Smith, Helen, Capper, David, Pfister, Stefan M., Würdinger, Thomas, Tam, Rachel, Garcia, Josep, Thakur, Meghna Das, Vassal, Gilles, Grill, Jacques, Jaspan, Tim, Varlet, Pascale, Jones, Chris
Publicado 2018

The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP)

por Velasco, Pablo, Bautista, Francisco, Rubio, Alba, Aguilar, Yurena, Rives, Susana, Dapena, Jose L., Pérez, Antonio, Ramirez, Manuel, Saiz-Ladera, Cristina, Izquierdo, Elisa, Escudero, Adela, Camós, Mireia, Vega-García, Nerea, Ortega, Margarita, Hidalgo-Gómez, Gloria, Palacio, Carlos, Menéndez, Pablo, Bueno, Clara, Montero, Joan, Romecín, Paola A., Zazo, Santiago, Alvarez, Federico, Parras, Juan, Ortega-Sabater, Carmen, Chulián, Salvador, Rosa, María, Cirillo, Davide, García, Elena, García, Jorge, Manzano-Muñoz, Albert, Minguela, Alfredo, Fuster, Jose L.
Publicado 2023

Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium

por Shern, Jack F., Selfe, Joanna, Izquierdo, Elisa, Patidar, Rajesh, Chou, Hsien-Chao, Song, Young K., Yohe, Marielle E., Sindiri, Sivasish, Wei, Jun, Wen, Xinyu, Rudzinski, Erin R., Barkauskas, Donald A., Lo, Tammy, Hall, David, Linardic, Corinne M., Hughes, Debbie, Jamal, Sabri, Jenney, Meriel, Chisholm, Julia, Brown, Rebecca, Jones, Kristine, Hicks, Belynda, Angelini, Paola, George, Sally, Chesler, Louis, Hubank, Michael, Kelsey, Anna, Gatz, Susanne A., Skapek, Stephen X., Hawkins, Douglas S., Shipley, Janet M., Khan, Javed
Publicado 2021

A tailored molecular profiling programme for children with cancer to identify clinically actionable genetic alterations

por George, Sally L., Izquierdo, Elisa, Campbell, James, Koutroumanidou, Eleni, Proszek, Paula, Jamal, Sabri, Hughes, Deborah, Yuan, Lina, Marshall, Lynley V., Carceller, Fernando, Chisholm, Julia C., Vaidya, Sucheta, Mandeville, Henry, Angelini, Paola, Wasti, Ajla, Bexelius, Tomas, Thway, Khin, Gatz, Susanne A., Clarke, Matthew, Al-Lazikani, Bissan, Barone, Giuseppe, Anderson, John, Tweddle, Deborah A., Gonzalez, David, Walker, Brian A., Barton, Jack, Depani, Sarita, Eze, Jessica, Ahmed, Saira W., Moreno, Lucas, Pearson, Andrew, Shipley, Janet, Jones, Chris, Hargrave, Darren, Jacques, Thomas S., Hubank, Michael, Chesler, Louis
Publicado 2019

DIPG Harbors Alterations Targetable by MEK Inhibitors, with Acquired Resistance Mechanisms Overcome by Combinatorial Inhibition

por Izquierdo, Elisa, Carvalho, Diana M., Mackay, Alan, Temelso, Sara, Boult, Jessica K.R., Pericoli, Giulia, Fernandez, Elisabet, Das, Molina, Molinari, Valeria, Grabovska, Yura, Rogers, Rebecca F., Ajmone-Cat, Maria Antonietta, Proszek, Paula Z., Stubbs, Mark, Depani, Sarita, O'Hare, Patricia, Yu, Lu, Roumelioti, Georgia, Choudhary, Jyoti S., Clarke, Matthew, Fairchild, Amy R., Jacques, Thomas S., Grundy, Richard G., Howell, Lisa, Picton, Susan, Adamski, Jenny, Wilson, Shaun, Gray, Juliet C., Zebian, Bassel, Marshall, Lynley V., Carceller, Fernando, Grill, Jacques, Vinci, Maria, Robinson, Simon P., Hubank, Michael, Hargrave, Darren, Jones, Chris
Publicado 2022

Molecular Characterization of Circulating Tumor DNA in Pediatric Rhabdomyosarcoma: A Feasibility Study

por Ruhen, Olivia, Lak, Nathalie S.M., Stutterheim, Janine, Danielli, Sara G., Chicard, Mathieu, Iddir, Yasmine, Saint-Charles, Alexandra, Di Paolo, Virginia, Tombolan, Lucia, Gatz, Susanne A., Aladowicz, Ewa, Proszek, Paula, Jamal, Sabri, Stankunaite, Reda, Hughes, Deborah, Carter, Paul, Izquierdo, Elisa, Wasti, Ajla, Chisholm, Julia C., George, Sally L., Pace, Erika, Chesler, Louis, Aerts, Isabelle, Pierron, Gaelle, Zaidi, Sakina, Delattre, Olivier, Surdez, Didier, Kelsey, Anna, Hubank, Michael, Bonvini, Paolo, Bisogno, Gianni, Di Giannatale, Angela, Schleiermacher, Gudrun, Schäfer, Beat W., Tytgat, Godelieve A.M., Shipley, Janet
Publicado 2022

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

por Mackay, Alan, Burford, Anna, Carvalho, Diana, Izquierdo, Elisa, Fazal-Salom, Janat, Taylor, Kathryn R., Bjerke, Lynn, Clarke, Matthew, Vinci, Mara, Nandhabalan, Meera, Temelso, Sara, Popov, Sergey, Molinari, Valeria, Raman, Pichai, Waanders, Angela J., Han, Harry J., Gupta, Saumya, Marshall, Lynley, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C., Bridges, Leslie R., Martin, Andrew J., Al-Sarraj, Safa, Chandler, Christopher, Ng, Ho-Keung, Li, Xingang, Mu, Kun, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Kisljakov, Alexei N., Konovalov, Dmitry M., Moore, Andrew S., Carcaboso, Angel Montero, Sunol, Mariona, de Torres, Carmen, Cruz, Ofelia, Mora, Jaume, Shats, Ludmila I., Stavale, João N., Bidinotto, Lucas T., Reis, Rui M., Entz-Werle, Natacha, Farrell, Michael, Cryan, Jane, Crimmins, Darach, Caird, John, Pears, Jane, Monje, Michelle, Debily, Marie-Anne, Castel, David, Grill, Jacques, Hawkins, Cynthia, Nikbakht, Hamid, Jabado, Nada, Baker, Suzanne J., Pfister, Stefan M., Jones, David T.W., Fouladi, Maryam, von Bueren, André O., Baudis, Michael, Resnick, Adam, Jones, Chris
Publicado 2017