High Prevalence of Insulin Resistance in Asymptomatic Patients with Acute Intermittent Porphyria and Liver-Targeted Insulin as a Novel Therapeutic Approach

por Solares, Isabel, Izquierdo-Sánchez, Laura, Morales-Conejo, Montserrat, Jericó, Daniel, Castelbón, Francisco Javier, Córdoba, Karol Marcela, Sampedro, Ana, Lumbreras, Carlos, Moreno-Aliaga, María Jesús, Enríquez de Salamanca, Rafael, Berraondo, Pedro, Fontanellas, Antonio
Publicado 2021

Inhibition of NAE‐dependent protein hyper‐NEDDylation in cystic cholangiocytes halts cystogenesis in experimental models of polycystic liver disease

por Lee‐Law, Pui Y., Olaizola, Paula, Caballero‐Camino, Francisco J., Izquierdo‐Sanchez, Laura, Rodrigues, Pedro M., Perugorria, Maria J., Azkargorta, Mikel, Elortza, Felix, Martinez‐Chantar, Maria L., Aspichueta, Patricia, Marzioni, Marco, Bujanda, Luis, Drenth, Joost P. H., Banales, Jesus M.
Publicado 2021

Association between Metabolic Disorders and Cholangiocarcinoma: Impact of a Postulated Risk Factor with Rising Incidence

por Da Fonseca, Leonardo G., Hashizume, Pedro H., de Oliveira, Irai Santana, Izquierdo-Sanchez, Laura, Saud, Lisa Rodrigues da Cunha, Xerfan, Mariana Pinheiro, Alves, Venancio Avancini Ferreira, de Mello, Evandro Sobroza, Herman, Paulo, Banales, Jesus M., Oliveira, Claudia P., Carrilho, Flair J.
Publicado 2022

Targeting UBC9-mediated protein hyper-SUMOylation in cystic cholangiocytes halts polycystic liver disease in experimental models

por Lee-Law, Pui Y., Olaizola, Paula, Caballero-Camino, Francisco J., Izquierdo-Sanchez, Laura, Rodrigues, Pedro M., Santos-Laso, Alvaro, Azkargorta, Mikel, Elortza, Felix, Martinez-Chanta, Maria L., Perugorria, Maria J., Aspichueta, Patricia, Marzioni, Marco, LaRusso, Nicholas F., Bujanda, Luis, Drenth, Joost P.H., Banales, Jesus M.
Publicado 2020

Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry

por Nooijen, Lynn E., Banales, Jesus M., de Boer, Marieke T., Braconi, Chiara, Folseraas, Trine, Forner, Alejandro, Holowko, Waclaw, Hoogwater, Frederik J. H., Klümpen, Heinz-Josef, Groot Koerkamp, Bas, Lamarca, Angela, La Casta, Adelaida, López-López, Flora, Izquierdo-Sánchez, Laura, Scheiter, Alexander, Utpatel, Kirsten, Swijnenburg, Rutger-Jan, Kazemier, Geert, Erdmann, Joris I.
Publicado 2022

A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans

por Caballero-Camino, Francisco J., Rodrigues, Pedro M., Wångsell, Fredrik, Agirre-Lizaso, Aloña, Olaizola, Paula, Izquierdo-Sanchez, Laura, Perugorria, Maria J., Bujanda, Luis, Angelin, Bo, Straniero, Sara, Wallebäck, Anna, Starke, Ingemar, Gillberg, Per-Göran, Strängberg, Ellen, Bonn, Britta, Mattsson, Jan P., Madsen, Martin R., Hansen, Henrik H., Lindström, Erik, Åkerblad, Peter, Banales, Jesus M.
Publicado 2023

Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease

por Caballero‐Camino, Francisco J., Rivilla, Ivan, Herraez, Elisa, Briz, Oscar, Santos‐Laso, Alvaro, Izquierdo‐Sanchez, Laura, Lee‐Law, Pui Y., Rodrigues, Pedro M., Munoz‐Garrido, Patricia, Jin, Sujeong, Peixoto, Estanislao, Richard, Seth, Gradilone, Sergio A., Perugorria, Maria J., Esteller, Manel, Bujanda, Luis, Marin, Jose J.G., Banales, Jesus M., Cossío, Fernando P.
Publicado 2020

Cirrhosis is associated with lower serological responses to COVID-19 vaccines in patients with chronic liver disease

por Simão, André Lopes, Palma, Carolina Santos, Izquierdo-Sanchez, Laura, Putignano, Antonella, Carvalho-Gomes, Angela, Posch, Andreas, Zanaga, Paola, Girleanu, Irina, Henrique, Mariana Moura, Araújo, Carlos, Degre, Delphine, Gustot, Thierry, Sahuco, Iván, Spagnolo, Elia, Carvalhana, Sofia, Moura, Miguel, Fernandes, Diogo AE., Banales, Jesus M., Romero-Gomez, Manuel, Trifan, Anca, Russo, Francesco Paolo, Stauber, Rudolf, Berenguer, Marina, Moreno, Christophe, Gonçalves, João, Cortez-Pinto, Helena, Castro, Rui E.
Publicado 2023

Presence of cirrhosis in chronic liver disease patients associates with a lower immune response to COVID-19 vaccines-a multicenter european study

por Simão, André L., Palma, Carolina Santos, Izquierdo-Sánchez, Laura, Putignano, Antonella, Carvalho-Gomes, Ângela, Posch, Andreas, Zanaga, Paola, Girleanu, Irina, Araújo, Carlos, Delphine, Degré, Gustot, Thierry, Sahuco, Iván, Spagnolo, Elia, Carvalhana, Sofia, Moura, Miguel, Henrique, Mariana Moura, Fernandes, Diogo A.E, Marques, Francisco, Banales, Jesus Maria, Gomez, Manuel Romero, Trifan, Anca, Russo, Francesco Paolo, Stauber, Rudolf E., Berenguer, Marina, Moreno, Christophe, Gonçalves, João, Cortez-Pinto, Helena, Castro, Rui
Publicado 2022

Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease...

por Lapitz, Ainhoa, Arbelaiz, Ander, O’Rourke, Colm J., Lavin, Jose L., La Casta, Adelaida, Ibarra, Cesar, Jimeno, Juan P., Santos-Laso, Alvaro, Izquierdo-Sanchez, Laura, Krawczyk, Marcin, Perugorria, Maria J., Jimenez-Aguero, Raul, Sanchez-Campos, Alberto, Riaño, Ioana, Gónzalez, Esperanza, Lammert, Frank, Marzioni, Marco, Macias, Rocio I.R., Marin, Jose J.G., Karlsen, Tom H., Bujanda, Luis, Falcón-Pérez, Juan M., Andersen, Jesper B., Aransay, Ana M., Rodrigues, Pedro M., Banales, Jesus M.
Publicado 2020

Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma

por Lapitz, Ainhoa, Azkargorta, Mikel, Milkiewicz, Piotr, Olaizola, Paula, Zhuravleva, Ekaterina, Grimsrud, Marit M., Schramm, Christoph, Arbelaiz, Ander, O'Rourke, Colm J., La Casta, Adelaida, Milkiewicz, Malgorzata, Pastor, Tania, Vesterhus, Mette, Jimenez-Agüero, Raul, Dill, Michael T., Lamarca, Angela, Valle, Juan W., Macias, Rocio I.R., Izquierdo-Sanchez, Laura, Pérez Castaño, Ylenia, Caballero-Camino, Francisco Javier, Riaño, Ioana, Krawczyk, Marcin, Ibarra, Cesar, Bustamante, Javier, Nova-Camacho, Luiz M., Falcon-Perez, Juan M., Elortza, Felix, Perugorria, Maria J., Andersen, Jesper B., Bujanda, Luis, Karlsen, Tom H., Folseraas, Trine, Rodrigues, Pedro M., Banales, Jesus M.
Publicado 2023

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

por Martínez‐Arranz, Ibon, Bruzzone, Chiara, Noureddin, Mazen, Gil‐Redondo, Ruben, Mincholé, Itziar, Bizkarguenaga, Maider, Arretxe, Enara, Iruarrizaga‐Lejarreta, Marta, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Mayo, Rebeca, Embade, Nieves, Newberry, Elizabeth, Mittendorf, Bettina, Izquierdo‐Sánchez, Laura, Smid, Vaclav, Arnold, Jorge, Iruzubieta, Paula, Pérez Castaño, Ylenia, Krawczyk, Marcin, Marigorta, Urko M., Morrison, Martine C., Kleemann, Robert, Martín‐Duce, Antonio, Hayardeny, Liat, Vitek, Libor, Bruha, Radan, Aller de la Fuente, Rocío, Crespo, Javier, Romero‐Gomez, Manuel, Banales, Jesus M, Arrese, Marco, Cusi, Kenneth, Bugianesi, Elisabetta, Klein, Samuel, Lu, Shelly C., Anstee, Quentin M., Millet, Oscar, Davidson, Nicholas O., Alonso, Cristina, Mato, José M.
Publicado 2022

Genomewide Association Study of Severe Covid-19 with Respiratory Failure

por Ellinghaus, David, Degenhardt, Frauke, Bujanda, Luis, Buti, Maria, Albillos, Agustín, Invernizzi, Pietro, Fernández, Javier, Prati, Daniele, Baselli, Guido, Asselta, Rosanna, Grimsrud, Marit M., Milani, Chiara, Aziz, Fátima, Kässens, Jan, May, Sandra, Wendorff, Mareike, Wienbrandt, Lars, Uellendahl-Werth, Florian, Zheng, Tenghao, Yi, Xiaoli, de Pablo, Raúl, Chercoles, Adolfo G., Palom, Adriana, Garcia-Fernandez, Alba-Estela, Rodriguez-Frias, Francisco, Zanella, Alberto, Bandera, Alessandra, Protti, Alessandro, Aghemo, Alessio, Lleo, Ana, Biondi, Andrea, Caballero-Garralda, Andrea, Gori, Andrea, Tanck, Anja, Carreras Nolla, Anna, Latiano, Anna, Fracanzani, Anna Ludovica, Peschuck, Anna, Julià, Antonio, Pesenti, Antonio, Voza, Antonio, Jiménez, David, Mateos, Beatriz, Nafria Jimenez, Beatriz, Quereda, Carmen, Paccapelo, Cinzia, Gassner, Christoph, Angelini, Claudio, Cea, Cristina, Solier, Aurora, Pestaña, David, Muñiz-Diaz, Eduardo, Sandoval, Elena, Paraboschi, Elvezia M., Navas, Enrique, García Sánchez, Félix, Ceriotti, Ferruccio, Martinelli-Boneschi, Filippo, Peyvandi, Flora, Blasi, Francesco, Téllez, Luis, Blanco-Grau, Albert, Hemmrich-Stanisak, Georg, Grasselli, Giacomo, Costantino, Giorgio, Cardamone, Giulia, Foti, Giuseppe, Aneli, Serena, Kurihara, Hayato, ElAbd, Hesham, My, Ilaria, Galván-Femenia, Iván, Martín, Javier, Erdmann, Jeanette, Ferrusquía-Acosta, Jose, Garcia-Etxebarria, Koldo, Izquierdo-Sanchez, Laura, Bettini, Laura R., Sumoy, Lauro, Terranova, Leonardo, Moreira, Leticia, Santoro, Luigi, Scudeller, Luigia, Mesonero, Francisco, Roade, Luisa, Rühlemann, Malte C., Schaefer, Marco, Carrabba, Maria, Riveiro-Barciela, Mar, Figuera Basso, Maria E., Valsecchi, Maria G., Hernandez-Tejero, María, Acosta-Herrera, Marialbert, D’Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Schulzky, Martin, Cecconi, Maurizio, Wittig, Michael, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Montano, Nicola, Braun, Nicole, Sacchi, Nicoletta, Martínez, Nilda, Özer, Onur, Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M., Blandino Ortiz, Aaron, de Cid, Rafael, Ferrer, Ricard, Gualtierotti, Roberta, Nieto, Rosa, Goerg, Siegfried, Badalamenti, Salvatore, Marsal, Sara, Matullo, Giuseppe, Pelusi, Serena, Juzenas, Simonas, Aliberti, Stefano, Monzani, Valter, Moreno, Victor, Wesse, Tanja, Lenz, Tobias L., Pumarola, Tomas, Rimoldi, Valeria, Bosari, Silvano, Albrecht, Wolfgang, Peter, Wolfgang, Romero-Gómez, Manuel, D’Amato, Mauro, Duga, Stefano, Banales, Jesus M., Hov, Johannes R, Folseraas, Trine, Valenti, Luca, Franke, Andre, Karlsen, Tom H.
Publicado 2020

Detailed stratified GWAS analysis for severe COVID-19 in four European populations

por Degenhardt, Frauke, Ellinghaus, David, Juzenas, Simonas, Lerga-Jaso, Jon, Wendorff, Mareike, Maya-Miles, Douglas, Uellendahl-Werth, Florian, ElAbd, Hesham, Rühlemann, Malte C, Arora, Jatin, Özer, Onur, Lenning, Ole Bernt, Myhre, Ronny, Vadla, May Sissel, Wacker, Eike M, Wienbrandt, Lars, Blandino Ortiz, Aaron, de Salazar, Adolfo, Garrido Chercoles, Adolfo, Palom, Adriana, Ruiz, Agustín, Garcia-Fernandez, Alba-Estela, Blanco-Grau, Albert, Mantovani, Alberto, Zanella, Alberto, Holten, Aleksander Rygh, Mayer, Alena, Bandera, Alessandra, Cherubini, Alessandro, Protti, Alessandro, Aghemo, Alessio, Gerussi, Alessio, Ramirez, Alfredo, Braun, Alice, Nebel, Almut, Barreira, Ana, Lleo, Ana, Teles, Ana, Kildal, Anders Benjamin, Biondi, Andrea, Caballero-Garralda, Andrea, Ganna, Andrea, Gori, Andrea, Glück, Andreas, Lind, Andreas, Tanck, Anja, Hinney, Anke, Carreras Nolla, Anna, Fracanzani, Anna Ludovica, Peschuck, Anna, Cavallero, Annalisa, Dyrhol-Riise, Anne Ma, Ruello, Antonella, Julià, Antonio, Muscatello, Antonio, Pesenti, Antonio, Voza, Antonio, Rando-Segura, Ariadna, Solier, Aurora, Schmidt, Axel, Cortes, Beatriz, Mateos, Beatriz, Nafria-Jimenez, Beatriz, Schaefer, Benedikt, Jensen, Björn, Bellinghausen, Carla, Maj, Carlo, Ferrando, Carlos, de la Horra, Carmen, Quereda, Carmen, Skurk, Carsten, Thibeault, Charlotte, Scollo, Chiara, Herr, Christian, Spinner, Christoph D, Gassner, Christoph, Lange, Christoph, Hu, Cinzia, Paccapelo, Cinzia, Lehmann, Clara, Angelini, Claudio, Cappadona, Claudio, Azuure, Clinton, Bianco, Cristiana, Cea, Cristina, Sancho, Cristina, Hoff, Dag Arne Lihaug, Galimberti, Daniela, Prati, Daniele, Haschka, David, Jiménez, David, Pestaña, David, Toapanta, David, Muñiz-Diaz, Eduardo, Azzolini, Elena, Sandoval, Elena, Binatti, Eleonora, Scarpini, Elio, Helbig, Elisa T, Casalone, Elisabetta, Urrechaga, Eloisa, Paraboschi, Elvezia Maria, Pontali, Emanuele, Reverter, Enric, Calderón, Enrique J, Navas, Enrique, Solligård, Erik, Contro, Ernesto, Arana-Arri, Eunate, Aziz, Fátima, Garcia, Federico, García Sánchez, Félix, Ceriotti, Ferruccio, Martinelli-Boneschi, Filippo, Peyvandi, Flora, Kurth, Florian, Blasi, Francesco, Malvestiti, Francesco, Medrano, Francisco J, Mesonero, Francisco, Rodriguez-Frias, Francisco, Hanses, Frank, Müller, Fredrik, Hemmrich-Stanisak, Georg, Bellani, Giacomo, Grasselli, Giacomo, Pezzoli, Gianni, Costantino, Giorgio, Albano, Giovanni, Cardamone, Giulia, Bellelli, Giuseppe, Citerio, Giuseppe, Foti, Giuseppe, Lamorte, Giuseppe, Matullo, Giuseppe, Baselli, Guido, Kurihara, Hayato, Neb, Holger, My, Ilaria, Kurth, Ingo, Hernández, Isabel, Pink, Isabell, de Rojas, Itziar, Galván-Femenia, Iván, Holter, Jan Cato, Afset, Jan Egil, Heyckendorf, Jan, Kässens, Jan, Damås, Jan Kristian, Rybniker, Jan, Altmüller, Janine, Ampuero, Javier, Martín, Javier, Erdmann, Jeanette, Banales, Jesus M, Badia, Joan Ramon, Dopazo, Joaquin, Schneider, Jochen, Bergan, Jonas, Barretina, Jordi, Walter, Jörn, Hernández Quero, Jose, Goikoetxea, Josune, Delgado, Juan, Guerrero, Juan M, Fazaal, Julia, Kraft, Julia, Schröder, Julia, Risnes, Kari, Banasik, Karina, Müller, Karl Erik, Gaede, Karoline I, Garcia-Etxebarria, Koldo, Tonby, Kristian, Heggelund, Lars, Izquierdo-Sanchez, Laura, Bettini, Laura Rachele, Sumoy, Lauro, Sander, Leif Erik, Lippert, Lena J, Terranova, Leonardo, Nkambule, Lindokuhle, Knopp, Lisa, Gustad, Lise Tuset, Garbarino, Lucia, Santoro, Luigi, Téllez, Luis, Roade, Luisa, Ostadreza, Mahnoosh, Intxausti, Maider, Kogevinas, Manolis, Riveiro-Barciela, Mar, Berger, Marc M, Schaefer, Marco, Niemi, Mari E K, Gutiérrez-Stampa, María A, Carrabba, Maria, Figuera Basso, Maria E, Valsecchi, Maria Grazia, Hernandez-Tejero, María, Vehreschild, Maria J G T, Manunta, Maria, Acosta-Herrera, Marialbert, D'Angiò, Mariella, Baldini, Marina, Cazzaniga, Marina, Grimsrud, Marit M, Cornberg, Markus, Nöthen, Markus M, Marquié, Marta, Castoldi, Massimo, Cordioli, Mattia, Cecconi, Maurizio, D'Amato, Mauro, Augustin, Max, Tomasi, Melissa, Boada, Mercè, Dreher, Michael, Seilmaier, Michael J, Joannidis, Michael, Wittig, Michael, Mazzocco, Michela, Ciccarelli, Michele, Rodríguez-Gandía, Miguel, Bocciolone, Monica, Miozzo, Monica, Imaz Ayo, Natale, Blay, Natalia, Chueca, Natalia, Montano, Nicola, Braun, Nicole, Ludwig, Nicole, Marx, Nikolaus, Martínez, Nilda, Cornely, Oliver A, Witzke, Oliver, Palmieri, Orazio, Faverio, Paola, Preatoni, Paoletta, Bonfanti, Paolo, Omodei, Paolo, Tentorio, Paolo, Castro, Pedro, Rodrigues, Pedro M, España, Pedro Pablo, Hoffmann, Per, Rosenstiel, Philip, Schommers, Philipp, Suwalski, Phillip, de Pablo, Raúl, Ferrer, Ricard, Bals, Robert, Gualtierotti, Roberta, Gallego-Durán, Rocío, Nieto, Rosa, Carpani, Rossana, Morilla, Rubén, Badalamenti, Salvatore, Haider, Sammra, Ciesek, Sandra, May, Sandra, Bombace, Sara, Marsal, Sara, Pigazzini, Sara, Klein, Sebastian, Pelusi, Serena, Wilfling, Sibylle, Bosari, Silvano, Volland, Sonja, Brunak, Søren, Raychaudhuri, Soumya, Schreiber, Stefan, Heilmann-Heimbach, Stefanie, Aliberti, Stefano, Ripke, Stephan, Dudman, Susanne, Wesse, Tanja, Zheng, Tenghao, Bahmer, Thomas, Eggermann, Thomas, Illig, Thomas, Brenner, Thorsten, Pumarola, Tomas, Feldt, Torsten, Folseraas, Trine, Gonzalez Cejudo, Trinidad, Landmesser, Ulf, Protzer, Ulrike, Hehr, Ute, Rimoldi, Valeria, Monzani, Valter, Skogen, Vegard, Keitel, Verena, Kopfnagel, Verena, Friaza, Vicente, Andrade, Victor, Moreno, Victor, Albrecht, Wolfgang, Peter, Wolfgang, Poller, Wolfgang, Farre, Xavier, Yi, Xiaoli, Wang, Xiaomin, Khodamoradi, Yascha, Karadeniz, Zehra, Latiano, Anna, Goerg, Siegfried, Bacher, Petra, Koehler, Philipp, Tran, Florian, Zoller, Heinz, Schulte, Eva C, Heidecker, Bettina, Ludwig, Kerstin U, Fernández, Javier, Romero-Gómez, Manuel, Albillos, Agustín, Invernizzi, Pietro, Buti, Maria, Duga, Stefano, Bujanda, Luis, Hov, Johannes R, Lenz, Tobias L, Asselta, Rosanna, de Cid, Rafael, Valenti, Luca, Karlsen, Tom H, Cáceres, Mario, Franke, Andre
Publicado 2022