Aldehyde Oxidase: Reaction Mechanism and Prediction of Site of Metabolism

por Montefiori, Marco, Jørgensen, Flemming Steen, Olsen, Lars
Publicado 2017

A Steered Molecular Dynamics Study of Binding and Translocation Processes in the GABA Transporter

por Skovstrup, Søren, David, Laurent, Taboureau, Olivier, Jørgensen, Flemming Steen
Publicado 2012

Fast Methods for Prediction of Aldehyde Oxidase-Mediated Site-of-Metabolism

por Montefiori, Marco, Lyngholm-Kjærby, Casper, Long, Anthony, Olsen, Lars, Jørgensen, Flemming Steen
Publicado 2019

Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment

por Wróbel, Tomasz M., Jørgensen, Flemming Steen, Pandey, Amit V., Grudzińska, Angelika, Sharma, Katyayani, Yakubu, Jibira, Björkling, Fredrik
Publicado 2023

Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors

por Bonomo, Silvia, Hansen, Cecilie H., Petrunak, Elyse M., Scott, Emily E., Styrishave, Bjarne, Jørgensen, Flemming Steen, Olsen, Lars
Publicado 2016

Synthesis and Antiangiogenic Activity of N-Alkylated Levamisole Derivatives

por Hansen, Anders N., Bendiksen, Christine D., Sylvest, Lene, Friis, Tina, Staerk, Dan, Jørgensen, Flemming Steen, Olsen, Christian A., Houen, Gunnar
Publicado 2012

The low binding affinity of D-serine at the ionotropic glutamate receptor GluD2 can be attributed to the hinge region

por Tapken, Daniel, Steffensen, Thomas Bielefeldt, Leth, Rasmus, Kristensen, Lise Baadsgaard, Gerbola, Alexander, Gajhede, Michael, Jørgensen, Flemming Steen, Olsen, Lars, Kastrup, Jette Sandholm
Publicado 2017

Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

por Alifrangis, Michael, Christensen, Inge T, Jørgensen, Flemming S, Rønn, Anita M, Weng, Jimmy E, Chen, Ming, Bygbjerg, Ib C, Sirawaraporn, Worachart, Palarasah, Yaseelan, Koch, Claus
Publicado 2004

Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

por Frydenvang, Karla, Verkade-Vreeker, Marlies C. A., Dohmen, Floor, Commandeur, Jan N. M., Rafiq, Maria, Mirza, Osman, Jørgensen, Flemming Steen, Geerke, Daan P.
Publicado 2019

Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents

por Wróbel, Tomasz M., Rogova, Oksana, Andersen, Kasper L., Yadav, Rahul, Brixius-Anderko, Simone, Scott, Emily E., Olsen, Lars, Jørgensen, Flemming Steen, Björkling, Fredrik
Publicado 2020

Synthesis and Structure–Activity Relationships of Novel Non-Steroidal CYP17A1 Inhibitors as Potential Prostate Cancer Agents

por Wróbel, Tomasz M., Rogova, Oksana, Sharma, Katyayani, Rojas Velazquez, Maria Natalia, Pandey, Amit V., Jørgensen, Flemming Steen, Arendrup, Frederic S., Andersen, Kasper L., Björkling, Fredrik
Publicado 2022

Itraconazole Reverts ABCB1-Mediated Docetaxel Resistance in Prostate Cancer

por Lima, Thiago S., Souza, Luciano O., Iglesias-Gato, Diego, Elversang, Johanna, Jørgensen, Flemming Steen, Kallunki, Tuula, Røder, Martin A., Brasso, Klaus, Moreira, José M.A.
Publicado 2022

An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants

por Wulff, Nikolai, Ernst, Heidi Asschenfeldt, Jørgensen, Morten Egevang, Lambertz, Sophie, Maierhofer, Tobias, Belew, Zeinu Mussa, Crocoll, Christoph, Motawia, Mohammed Saddik, Geiger, Dietmar, Jørgensen, Flemming Steen, Mirza, Osman, Nour-Eldin, Hussam Hassan
Publicado 2019

Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis

por Wróbel, Tomasz M., Sharma, Katyayani, Mannella, Iole, Oliaro-Bosso, Simonetta, Nieckarz, Patrycja, Du Toit, Therina, Voegel, Clarissa Daniela, Rojas Velazquez, Maria Natalia, Yakubu, Jibira, Matveeva, Anna, Therkelsen, Søren, Jørgensen, Flemming Steen, Pandey, Amit V., Pippione, Agnese C., Lolli, Marco L., Boschi, Donatella, Björkling, Fredrik
Publicado 2023

Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase

por Jensen, Simon Bo, Thodberg, Sara, Parween, Shaheena, Moses, Matias E., Hansen, Cecilie C., Thomsen, Johannes, Sletfjerding, Magnus B., Knudsen, Camilla, Del Giudice, Rita, Lund, Philip M., Castaño, Patricia R., Bustamante, Yanet G., Velazquez, Maria Natalia Rojas, Jørgensen, Flemming Steen, Pandey, Amit V., Laursen, Tomas, Møller, Birger Lindberg, Hatzakis, Nikos S.
Publicado 2021