XIAP-mediated Caspase Inhibition in Hodgkin's Lymphoma–derived B Cells

por Kashkar, Hamid, Haefs, Christiane, Shin, Hwain, Hamilton-Dutoit, Stephen J., Salvesen, Guy S., Krönke, Martin, Jürgensmeier, Juliane M.
Publicado 2003

IDH1-Associated Primary Glioblastoma in Young Adults Displays Differential Patterns of Tumour and Vascular Morphology

por Popov, Sergey, Jury, Alexa, Laxton, Ross, Doey, Lawrence, Kandasamy, Naga, Al-Sarraj, Safa, Jürgensmeier, Juliane M., Jones, Chris
Publicado 2013

Distinct Phenotypic Differences Associated with Differential Amplification of Receptor Tyrosine Kinase Genes at 4q12 in Glioblastoma

por Burford, Anna, Little, Suzanne E., Jury, Alexa, Popov, Sergey, Laxton, Ross, Doey, Lawrence, Al-Sarraj, Safa, Jürgensmeier, Juliane M., Jones, Chris
Publicado 2013

Homogeneous BTK Occupancy Assay for Pharmacodynamic Assessment of Tirabrutinib (GS-4059/ONO-4059) Target Engagement

por Yu, Helen, Truong, Hoa, Mitchell, Scott A., Liclican, Albert, Gosink, John J., Li, Wanying, Lin, Julie, Feng, Joy Y., Jürgensmeier, Juliane M., Billin, Andrew, Xu, Ren, Patterson, Scott, Pagratis, Nikos
Publicado 2018

Semi‐Mechanistic PK/PD Modeling and Simulation of Irreversible BTK Inhibition to Support Dose Selection of Tirabrutinib in Subjects with RA

por Meng, Amy, Humeniuk, Rita, Jürgensmeier, Juliane M., Hsueh, Chia‐Hsiang, Matzkies, Franziska, Grant, Ethan, Truong, Hoa, Billin, Andrew N., Yu, Helen, Feng, Joy, Kwan, Ellen, Tarnowski, Thomas, Nelson, Cara H.
Publicado 2021

A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress

por Lee, Jong Woo, Park, Hee Sun, Park, Sin-Aye, Ryu, Seung-Hee, Meng, Wuyi, Jürgensmeier, Juliane M., Kurie, Jonathan M., Hong, Waun Ki, Boyer, Julie L., Herbst, Roy S., Koo, Ja Seok
Publicado 2015

Phase 1 first-in-human study of dalutrafusp alfa, an anti–CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors

por Tolcher, Anthony W, Gordon, Michael, Mahoney, Kathleen M, Seto, Anna, Zavodovskaya, Marianna, Hsueh, Chia-Hsiang, Zhai, Shuyan, Tarnowski, Thomas, Jürgensmeier, Juliane M, Stinson, Susanna, Othman, Ahmed A, Chen, Tianling, Strauss, James
Publicado 2023

Efficacy and Safety of the Combination of Tirabrutinib and Entospletinib With or Without Obinutuzumab in Relapsed Chronic Lymphocytic Leukemia

por Kutsch, Nadine, Pallasch, Christian, Tausch, Eugen, Böhme, Volkmar, Ritgen, Matthias, Liersch, Rüdiger, Wacker, Alexander, Jacobs, Georg, Trappe, Ralf Ulrich, Dreger, Peter, Fischer, Kirsten, Fink, Anna-Maria, Stilgenbauer, Stephan, Zhai, Shuyan, Li, Biao, Jürgensmeier, Juliane M., Rajakumaraswamy, Nishanthan, Bhargava, Pankaj, Hallek, Michael, Eichhorst, Barbara F.
Publicado 2022

Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma

por Morschhauser, Franck, Dyer, Martin J. S., Walter, Harriet S., Danilov, Alexey V., Ysebaert, Loic, Hodson, Daniel James, Fegan, Christopher, Rule, Simon A., Radford, John, Cartron, Guillaume, Bouabdallah, Krimo, Davies, Andrew John, Spurgeon, Stephen, Rajakumaraswamy, Nishanthan, Li, Biao, Humeniuk, Rita, Huang, Xi, Bhargava, Pankaj, Jürgensmeier, Juliane M., Salles, Gilles
Publicado 2020

Efficacy and Safety of Tirabrutinib and Idelalisib With or Without Obinutuzumab in Relapsed Chronic Lymphocytic Leukemia

por Kutsch, Nadine, Pallasch, Christian, Decker, Thomas, Hebart, Holger, Chow, Kai Uwe, Graeven, Ullrich, Kisro, Jens, Kroeber, Alexander, Tausch, Eugen, Fischer, Kirsten, Fink, Anna-Maria, Wendtner, Clemens-Martin, Ritgen, Matthias, Stilgenbauer, Stephan, Zhang, Danjie, Li, Biao, Jürgensmeier, Juliane M., Rajakumaraswamy, Nishanthan, Bhargava, Pankaj, Hallek, Michael, Eichhorst, Barbara
Publicado 2022