Translation of MT-ATP6 pathogenic variants reveals distinct regulatory consequences from the co-translational quality control of mitochondrial protein synthesis

por Ng, Kah Ying, Richter, Uwe, Jackson, Christopher B, Seneca, Sara, Battersby, Brendan J
Publicado 2021

Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice

por Gorski, Katarin, Jackson, Christopher B., Nyman, Tuula A., Rezov, Veronika, Battersby, Brendan J., Lehesjoki, Anna-Elina
Publicado 2023

Molecular Rapid Diagnostics Improve Time to Effective Therapy and Survival in Patients with Vancomycin-Resistant Enterococcus Bloodstream Infections

por Bandy, Sarah M., Jackson, Christopher B., Black, Cody A., Godinez, William, Gawrys, Gerard W., Lee, Grace C.
Publicado 2023

GTPBP8 is required for mitoribosomal biogenesis and mitochondrial translation

por Wang, Liang, Hilander, Taru, Liu, Xiaonan, Tsang, Hoi Ying, Eriksson, Ove, Jackson, Christopher B., Varjosalo, Markku, Zhao, Hongxia
Publicado 2023

Molecular and biochemical characterisation of a novel mutation in POLG associated with Alpers syndrome

por Schaller, André, Hahn, Dagmar, Jackson, Christopher B, Kern, Ilse, Chardot, Christophe, Belli, Dominique C, Gallati, Sabina, Nuoffer, Jean-Marc
Publicado 2011

3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids

por Beauchamp, Philippe, Jackson, Christopher B., Ozhathil, Lijo Cherian, Agarkova, Irina, Galindo, Cristi L., Sawyer, Douglas B., Suter, Thomas M., Zuppinger, Christian
Publicado 2020

Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy

por Ignatenko, Olesia, Chilov, Dmitri, Paetau, Ilse, de Miguel, Elena, Jackson, Christopher B., Capin, Gabrielle, Paetau, Anders, Terzioglu, Mugen, Euro, Liliya, Suomalainen, Anu
Publicado 2018

Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production

por Amini, Poorya, Stojkov, Darko, Felser, Andrea, Jackson, Christopher B., Courage, Carolina, Schaller, André, Gelman, Laurent, Soriano, Maria Eugenia, Nuoffer, Jean-Marc, Scorrano, Luca, Benarafa, Charaf, Yousefi, Shida, Simon, Hans-Uwe
Publicado 2018

Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs

por Gammage, Payam A., Gaude, Edoardo, Van Haute, Lindsey, Rebelo-Guiomar, Pedro, Jackson, Christopher B., Rorbach, Joanna, Pekalski, Marcin L., Robinson, Alan J., Charpentier, Marine, Concordet, Jean-Paul, Frezza, Christian, Minczuk, Michal
Publicado 2016

AB013. Treatment of thymic oligometastastic or oligoprogressive lesions with hypofractionated radiation therapy or stereotactic body radiation therapy

por Jackson, Christopher B., Rimner, Andreas, Simone, Charles B., Lebow, Emily S., Huang, James, Lobaugh, Stephanie M., Zhang, Zhigang, Riely, Gregory J., Ginsberg, Michelle S., Pagano, Andrew M., Chang, Jason C., Mayoral, Maria, Gomez, Daniel G., Shepherd, Annemarie F.
Publicado 2022

In-frame deletion in canine PITRM1 is associated with a severe early-onset epilepsy, mitochondrial dysfunction and neurodegeneration

por Hytönen, Marjo K., Sarviaho, Riika, Jackson, Christopher B., Syrjä, Pernilla, Jokinen, Tarja, Matiasek, Kaspar, Rosati, Marco, Dallabona, Cristina, Baruffini, Enrico, Quintero, Ileana, Arumilli, Meharji, Monteuuis, Geoffray, Donner, Jonas, Anttila, Marjukka, Suomalainen, Anu, Bindoff, Laurence A., Lohi, Hannes
Publicado 2021

SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

por Gut, Philipp, Matilainen, Sanna, Meyer, Jesse G., Pällijeff, Pieti, Richard, Joy, Carroll, Christopher J., Euro, Liliya, Jackson, Christopher B., Isohanni, Pirjo, Minassian, Berge A., Alkhater, Reem A., Østergaard, Elsebet, Civiletto, Gabriele, Parisi, Alice, Thevenet, Jonathan, Rardin, Matthew J., He, Wenjuan, Nishida, Yuya, Newman, John C., Liu, Xiaojing, Christen, Stefan, Moco, Sofia, Locasale, Jason W., Schilling, Birgit, Suomalainen, Anu, Verdin, Eric
Publicado 2020

Deficiency of ECHS1 causes mitochondrial encephalopathy with cardiac involvement

por Haack, Tobias B, Jackson, Christopher B, Murayama, Kei, Kremer, Laura S, Schaller, André, Kotzaeridou, Urania, de Vries, Maaike C, Schottmann, Gudrun, Santra, Saikat, Büchner, Boriana, Wieland, Thomas, Graf, Elisabeth, Freisinger, Peter, Eggimann, Sandra, Ohtake, Akira, Okazaki, Yasushi, Kohda, Masakazu, Kishita, Yoshihito, Tokuzawa, Yoshimi, Sauer, Sascha, Memari, Yasin, Kolb-Kokocinski, Anja, Durbin, Richard, Hasselmann, Oswald, Cremer, Kirsten, Albrecht, Beate, Wieczorek, Dagmar, Engels, Hartmut, Hahn, Dagmar, Zink, Alexander M, Alston, Charlotte L, Taylor, Robert W, Rodenburg, Richard J, Trollmann, Regina, Sperl, Wolfgang, Strom, Tim M, Hoffmann, Georg F, Mayr, Johannes A, Meitinger, Thomas, Bolognini, Ramona, Schuelke, Markus, Nuoffer, Jean-Marc, Kölker, Stefan, Prokisch, Holger, Klopstock, Thomas
Publicado 2015