Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment

por Jackson, Lindsey M, Moldovan, George-Lucian
Publicado 2022

The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells

por Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Khatib, Jude B., Nicolae, Claudia M., Moldovan, George-Lucian
Publicado 2022

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival

por Khatib, Jude B., Schleicher, Emily M., Jackson, Lindsey M., Dhoonmoon, Ashna, Moldovan, George-Lucian, Nicolae, Claudia M.
Publicado 2022

Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells

por Jackson, Lindsey M, Dhoonmoon, Ashna, Hale, Anastasia, Dennis, Kady A, Schleicher, Emily M, Nicolae, Claudia M, Moldovan, George-Lucian
Publicado 2021

Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitors

por Schleicher, Emily M., Dhoonmoon, Ashna, Jackson, Lindsey M., Clements, Kristen E., Stump, Coryn L., Nicolae, Claudia M., Moldovan, George-Lucian
Publicado 2020

An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

por Morley, Valerie J, Kinnear, Clare L, Sim, Derek G, Olson, Samantha N, Jackson, Lindsey M, Hansen, Elsa, Usher, Grace A, Showalter, Scott A, Pai, Manjunath P, Woods, Robert J, Read, Andrew F
Publicado 2020