Etiology matters: genetic and acquired prion diseases engage different mechanisms at a presymptomatic stage

por Jackson, Walker S.
Publicado 2023

Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein

por Jackson, Walker S.
Publicado 2014

Peculiarities of Prion Diseases

por Jackson, Walker S., Krost, Clemens
Publicado 2014

The natural Disc1-deletion present in several inbred mouse strains does not affect sleep

por Dittrich, Lars, Petese, Alessandro, Jackson, Walker S.
Publicado 2017

Effect of Transcutaneous Spinal Direct Current Stimulation in Patients with Painful Polyneuropathy and Influence of Possible Predictors of Efficacy including BDNF Polymorphism: A R...

por Rahin, Hedayat, Jackson, Walker Scot, Thordstein, Magnus
Publicado 2023

Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9

por Kaczmarczyk, Lech, Mende, Ylva, Zevnik, Branko, Jackson, Walker S.
Publicado 2016

Translation of the Prion Protein mRNA Is Robust in Astrocytes but Does Not Amplify during Reactive Astrocytosis in the Mouse Brain

por Jackson, Walker S., Krost, Clemens, Borkowski, Andrew W., Kaczmarczyk, Lech
Publicado 2014

Translatome profiling in fatal familial insomnia implicates TOR signaling in somatostatin neurons

por Bauer, Susanne, Dittrich, Lars, Kaczmarczyk, Lech, Schleif, Melvin, Benfeitas, Rui, Jackson, Walker S
Publicado 2022

Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington’s disease mice

por Bauer, Susanne, Chen, Chwen-Yu, Jonson, Maria, Kaczmarczyk, Lech, Magadi, Srivathsa Subramanya, Jackson, Walker S.
Publicado 2023

Genetic human prion disease modelled in PrP transgenic Drosophila

por Thackray, Alana M., Cardova, Alzbeta, Wolf, Hanna, Pradl, Lydia, Vorberg, Ina, Jackson, Walker S., Bujdoso, Raymond
Publicado 2017

Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background

por Kaczmarczyk, Lech, Reichenbach, Nicole, Blank, Nelli, Jonson, Maria, Dittrich, Lars, Petzold, Gabor C., Jackson, Walker S.
Publicado 2021

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

por Kaczmarczyk, Lech, Bansal, Vikas, Rajput, Ashish, Rahman, Raza-ur, Krzyżak, Wiesław, Degen, Joachim, Poll, Stefanie, Fuhrmann, Martin, Bonn, Stefan, Jackson, Walker Scot
Publicado 2019

Correction: Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

por Kaczmarczyk, Lech, Bansal, Vikas, Rajput, Ashish, Rahman, Raza-ur, Krzyżak, Wiesław, Degen, Joachim, Poll, Stefanie, Fuhrmann, Martin, Bonn, Stefan, Jackson, Walker Scot
Publicado 2022

Heterozygosity for cervid S138N polymorphism results in subclinical CWD in gene-targeted mice and progressive inhibition of prion conversion

por Arifin, Maria I., Kaczmarczyk, Lech, Zeng, Doris, Hannaoui, Samia, Lee, Chi, Chang, Sheng Chun, Mitchell, Gordon, McKenzie, Debbie, Beekes, Michael, Jackson, Walker, Gilch, Sabine
Publicado 2023

Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein

por Linsenmeier, Luise, Mohammadi, Behnam, Wetzel, Sebastian, Puig, Berta, Jackson, Walker S., Hartmann, Alexander, Uchiyama, Keiji, Sakaguchi, Suehiro, Endres, Kristina, Tatzelt, Jörg, Saftig, Paul, Glatzel, Markus, Altmeppen, Hermann C.
Publicado 2018

Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease

por Vallabh, Sonia M., Zou, Dan, Pitstick, Rose, O’Moore, Jill, Peters, Janet, Silvius, Derek, Kriz, Jasna, Jackson, Walker S., Carlson, George A., Minikel, Eric Vallabh, Cabin, Deborah E.
Publicado 2023

Distinct translatome changes in specific neural populations precede electroencephalographic changes in prion-infected mice

por Kaczmarczyk, Lech, Schleif, Melvin, Dittrich, Lars, Williams, Rhiannan H., Koderman, Maruša, Bansal, Vikas, Rajput, Ashish, Schulte, Theresa, Jonson, Maria, Krost, Clemens, Testaquadra, Fabio J., Bonn, Stefan, Jackson, Walker S.
Publicado 2022

Clearance of variant Creutzfeldt–Jakob disease prions in vivo by the Hsp70 disaggregase system

por Thackray, Alana M, Lam, Brian, McNulty, Erin E, Nalls, Amy V, Mathiason, Candace K, Magadi, Srivathsa Subramanya, Jackson, Walker S, Andréoletti, Olivier, Marrero-Winkens, Cristóbal, Schätzl, Hermann, Bujdoso, Raymond
Publicado 2022

CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors

por Crittenden, Jill R., Zhai, Shenyu, Sauvage, Magdalena, Kitsukawa, Takashi, Burguière, Eric, Thomsen, Morgane, Zhang, Hui, Costa, Cinzia, Martella, Giuseppina, Ghiglieri, Veronica, Picconi, Barbara, Pescatore, Karen A., Unterwald, Ellen M., Jackson, Walker S., Housman, David E., Caine, S. Barak, Sulzer, David, Calabresi, Paolo, Smith, Anne C., Surmeier, D. James, Graybiel, Ann M.
Publicado 2021

Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice

por Xie, Kan, Ryan, Devon P., Pearson, Brandon L., Henzel, Kristin S., Neff, Frauke, Vidal, Ramon O., Hennion, Magali, Lehmann, Isabelle, Schleif, Melvin, Schröder, Susanne, Adler, Thure, Rathkolb, Birgit, Rozman, Jan, Schütz, Anna-Lena, Prehn, Cornelia, Mickael, Michel E., Weiergräber, Marco, Adamski, Jerzy, Busch, Dirk H., Ehninger, Gerhard, Matynia, Anna, Jackson, Walker S., Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, Bonn, Stefan, Hrabě de Angelis, Martin, Ehninger, Dan
Publicado 2018