AP4 is required for mitogen- and c-MYC-induced cell cycle progression

por Jackstadt, Rene, Hermeking, Heiko
Publicado 2014

Mouse models of intestinal cancer

por Jackstadt, Rene, Sansom, Owen J
Publicado 2015

The Wae to repair: prostaglandin E2 (PGE(2)) triggers intestinal wound repair

por Jackstadt, Rene, Sansom, Owen James
Publicado 2017

Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness

por Siemens, Helge, Jackstadt, Rene, Kaller, Markus, Hermeking, Heiko
Publicado 2013

Advances in colon cancer research: in vitro and animal models

por Lannagan, Tamsin RM, Jackstadt, Rene, Leedham, Simon J, Sansom, Owen J
Publicado 2021

Modeling Colorectal Cancer Progression Reveals Niche-Dependent Clonal Selection

por Vaquero-Siguero, Nuria, Schleussner, Nikolai, Volk, Julia, Mastel, Manuel, Meier, Jasmin, Jackstadt, Rene
Publicado 2022

Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts

por Cernat, Laura, Blaj, Cristina, Jackstadt, Rene, Brandl, Lydia, Engel, Jutta, Hermeking, Heiko, Jung, Andreas, Kirchner, Thomas, Horst, David
Publicado 2014

Ap4 is rate limiting for intestinal tumor formation by controlling the homeostasis of intestinal stem cells

por Jaeckel, Stephanie, Kaller, Markus, Jackstadt, Rene, Götz, Ursula, Müller, Susanna, Boos, Sophie, Horst, David, Jung, Peter, Hermeking, Heiko
Publicado 2018

Desmogleins as prognostic biomarkers in resected pancreatic ductal adenocarcinoma

por Ormanns, Steffen, Altendorf-Hofmann, Annelore, Jackstadt, Rene, Horst, David, Assmann, Gerald, Zhao, Yue, Bruns, Christiane, Kirchner, Thomas, Knösel, Thomas
Publicado 2015

AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer

por Jackstadt, Rene, Röh, Simone, Neumann, Jens, Jung, Peter, Hoffmann, Reinhard, Horst, David, Berens, Christian, Bornkamm, Georg W., Kirchner, Thomas, Menssen, Antje, Hermeking, Heiko
Publicado 2013

Active elimination of intestinal cells drives oncogenic growth in organoids

por Krotenberg Garcia, Ana, Fumagalli, Arianna, Le, Huy Quang, Jackstadt, Rene, Lannagan, Tamsin Rosemary Margaret, Sansom, Owen James, van Rheenen, Jacco, Suijkerbuijk, Saskia Jacoba Elisabeth
Publicado 2021

Microsatellite Instability, KRAS Mutations and Cellular Distribution of TRAIL-Receptors in Early Stage Colorectal Cancer

por Kriegl, Lydia, Jung, Andreas, Horst, David, Rizzani, Antonia, Jackstadt, Rene, Hermeking, Heiko, Gallmeier, Eike, Gerbes, Alexander L., Kirchner, Thomas, Göke, Burkhard, De Toni, Enrico N.
Publicado 2012

Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε

por Liffers, Sven-T, Maghnouj, Abdelouahid, Munding, Johanna B, Jackstadt, René, Herbrand, Ulrike, Schulenborg, Thomas, Marcus, Katrin, Klein-Scory, Susanne, Schmiegel, Wolff, Schwarte-Waldhoff, Irmgard, Meyer, Helmut E, Stühler, Kai, Hahn, Stephan A
Publicado 2011

Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer

por Gay, David M., Ridgway, Rachel A., Müller, Miryam, Hodder, Michael C., Hedley, Ann, Clark, William, Leach, Joshua D., Jackstadt, Rene, Nixon, Colin, Huels, David J., Campbell, Andrew D., Bird, Thomas G., Sansom, Owen J.
Publicado 2019

Author Correction: Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer

por Gay, David M., Ridgway, Rachel A., Müller, Miryam, Hodder, Michael C., Hedley, Ann, Clark, William, Leach, Joshua D., Jackstadt, Rene, Nixon, Colin, Huels, David J., Campbell, Andrew D., Bird, Thomas G., Sansom, Owen J.
Publicado 2019

BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer

por Ramesh, Prashanthi, Lannagan, Tamsin R. M., Jackstadt, Rene, Atencia Taboada, Lidia, Lansu, Nico, Wirapati, Pratyaksha, van Hooff, Sander R., Dekker, Danielle, Pritchard, Jessica, Kirov, Aleksandar B., van Neerven, Sanne M., Tejpar, Sabine, Kops, Geert J. P. L., Sansom, Owen J., Medema, Jan Paul
Publicado 2021

Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade

por Nielsen, Sebastian R., Strøbech, Jan E., Horton, Edward R., Jackstadt, Rene, Laitala, Anu, Bravo, Marina C., Maltese, Giorgia, Jensen, Adina R. D., Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A., Hwang, Chang-Il, Arnes, Luis, Tuveson, David A., Sansom, Owen J., Morton, Jennifer P., Erler, Janine T.
Publicado 2021

Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing

por Wittner, Leonie, Wagener, Lukas, Wiese, Jakob J., Stolzer, Iris, Krug, Susanne M., Naschberger, Elisabeth, Jackstadt, Rene, Beyaert, Rudi, Atreya, Raja, Kühl, Anja A., Sturm, Gregor, Gonzalez-Acera, Miguel, Patankar, Jay V., Becker, Christoph, Siegmund, Britta, Trajanoski, Zlatko, Winner, Beate, Neurath, Markus F., Schumann, Michael, Günther, Claudia
Publicado 2023

Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression

por Bailey, Peter, Ridgway, Rachel A., Cammareri, Patrizia, Treanor-Taylor, Mairi, Bailey, Ulla-Maja, Schoenherr, Christina, Bone, Max, Schreyer, Daniel, Purdie, Karin, Thomson, Jason, Rickaby, William, Jackstadt, Rene, Campbell, Andrew D., Dimonitsas, Emmanouil, Stratigos, Alexander J., Arron, Sarah T., Wang, Jun, Blyth, Karen, Proby, Charlotte M., Harwood, Catherine A., Sansom, Owen J., Leigh, Irene M., Inman, Gareth J.
Publicado 2023

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity

por Hutton, Colin, Heider, Felix, Blanco-Gomez, Adrian, Banyard, Antonia, Kononov, Alexander, Zhang, Xiaohong, Karim, Saadia, Paulus-Hock, Viola, Watt, Dale, Steele, Nina, Kemp, Samantha, Hogg, Elizabeth K.J., Kelly, Joanna, Jackstadt, Rene-Filip, Lopes, Filipa, Menotti, Matteo, Chisholm, Luke, Lamarca, Angela, Valle, Juan, Sansom, Owen J., Springer, Caroline, Malliri, Angeliki, Marais, Richard, Pasca di Magliano, Marina, Zelenay, Santiago, Morton, Jennifer P., Jørgensen, Claus
Publicado 2021