Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation

por Ferrari, Samuele, Vavassori, Valentina, Canarutto, Daniele, Jacob, Aurelien, Castiello, Maria Carmina, Javed, Attya Omer, Genovese, Pietro
Publicado 2021

Monobac System–A Single Baculovirus for the Production of rAAV

por Galibert, Lionel, Jacob, Aurélien, Savy, Adrien, Dickx, Yohann, Bonnin, Delphine, Lecomte, Christophe, Rivollet, Lise, Sanatine, Peggy, Boutin Fontaine, Marjorie, Le Bec, Christine, Merten, Otto-Wilhelm
Publicado 2021

Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells

por Omer-Javed, Attya, Pedrazzani, Gabriele, Albano, Luisa, Ghaus, Sherash, Latroche, Claire, Manzi, Maura, Ferrari, Samuele, Fiumara, Martina, Jacob, Aurelien, Vavassori, Valentina, Nonis, Alessandro, Canarutto, Daniele, Naldini, Luigi
Publicado 2022

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking

por Ferrari, Samuele, Jacob, Aurelien, Beretta, Stefano, Unali, Giulia, Albano, Luisa, Vavassori, Valentina, Cittaro, Davide, Lazarevic, Dejan, Brombin, Chiara, Cugnata, Federica, Kajaste-Rudnitski, Anna, Merelli, Ivan, Genovese, Pietro, Naldini, Luigi
Publicado 2020

Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4(+) T‐cells for the treatment of Hyper IgM1

por Canarutto, Daniele, Asperti, Claudia, Vavassori, Valentina, Porcellini, Simona, Rovelli, Elisabetta, Paulis, Marianna, Ferrari, Samuele, Varesi, Angelica, Fiumara, Martina, Jacob, Aurelien, Sergi Sergi, Lucia, Visigalli, Ilaria, Ferrua, Francesca, González‐Granado, Luis Ignacio, Lougaris, Vassilios, Finocchi, Andrea, Villa, Anna, Radrizzani, Marina, Naldini, Luigi
Publicado 2023

Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

por Schiroli, Giulia, Conti, Anastasia, Ferrari, Samuele, della Volpe, Lucrezia, Jacob, Aurelien, Albano, Luisa, Beretta, Stefano, Calabria, Andrea, Vavassori, Valentina, Gasparini, Patrizia, Salataj, Eralda, Ndiaye-Lobry, Delphine, Brombin, Chiara, Chaumeil, Julie, Montini, Eugenio, Merelli, Ivan, Genovese, Pietro, Naldini, Luigi, Di Micco, Raffaella
Publicado 2019

Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated in vitro and in vivo

por Asperti, Claudia, Canarutto, Daniele, Porcellini, Simona, Sanvito, Francesca, Cecere, Francesca, Vavassori, Valentina, Ferrari, Samuele, Rovelli, Elisabetta, Albano, Luisa, Jacob, Aurelien, Sergi Sergi, Lucia, Montaldo, Elisa, Ferrua, Francesca, González-Granado, Luis Ignacio, Lougaris, Vassilios, Badolato, Raffaele, Finocchi, Andrea, Villa, Anna, Radrizzani, Marina, Naldini, Luigi
Publicado 2023

Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells

por Ferrari, Samuele, Jacob, Aurelien, Cesana, Daniela, Laugel, Marianne, Beretta, Stefano, Varesi, Angelica, Unali, Giulia, Conti, Anastasia, Canarutto, Daniele, Albano, Luisa, Calabria, Andrea, Vavassori, Valentina, Cipriani, Carlo, Castiello, Maria Carmina, Esposito, Simona, Brombin, Chiara, Cugnata, Federica, Adjali, Oumeya, Ayuso, Eduard, Merelli, Ivan, Villa, Anna, Di Micco, Raffaella, Kajaste-Rudnitski, Anna, Montini, Eugenio, Penaud-Budloo, Magalie, Naldini, Luigi
Publicado 2022