Reflections on Darwinian Evolution – Is there a Jewish Perspective?

por Jacob, Chaim O.
Publicado 2011

Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge

por Armstrong, Don L, Jacob, Chaim O, Zidovetzki, Raphael
Publicado 2008

New Endothelial Mechanisms in Glomerular (Patho)biology and Proteinuria Development Captured by Intravital Multiphoton Imaging

por Gyarmati, Georgina, Jacob, Chaim O., Peti-Peterdi, János
Publicado 2021

Constitutive reduction in the checkpoint inhibitor, CTLA-4, does not accelerate SLE in NZM 2328 mice

por Stohl, William, Yu, Ning, Chalmers, Samantha A, Putterman, Chaim, Jacob, Chaim O
Publicado 2019

Admixture in Hispanic-Americans: Its impact on ITGAM association and implications for admixture mapping in SLE

por Molineros, Julio E., Kim-Howard, Xana, Deshmukh, Harshal, Jacob, Chaim O., Harley, John B., Nath, Swapan K.
Publicado 2009

Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice

por Chu, Seung Y., Pong, Erik, Bonzon, Christine, Yu, Ning, Jacob, Chaim O., Chalmers, Samantha A., Putterman, Chaim, Szymkowski, David E., Stohl, William
Publicado 2020

Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis

por Kadoya, Hiroyuki, Yu, Ning, Schiessl, Ina Maria, Riquier-Brison, Anne, Gyarmati, Georgina, Desposito, Dorinne, Kidokoro, Kengo, Butler, Matthew J., Jacob, Chaim O., Peti-Peterdi, János
Publicado 2020

IgG1 protects against renal disease in a mouse model of cryoglobulinemia

por Strait, Richard T., Posgai, Monica T., Mahler, Ashley, Barasa, Nathaniel, Jacob, Chaim O., Köhl, Jörg, Ehlers, Marc, Stringer, Keith, Shanmukappa, Shiva Kumar, Witte, David, Hossain, Md Monir, Khodoun, Marat, Herr, Andrew B., Finkelman, Fred D.
Publicado 2014

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

por Armstrong, Don L., Zidovetzki, Raphael, Alarcón-Riquelme, Marta E, Tsao, Betty P, Criswell, Lindsey A, Kimberly, Robert P, Harley, John B, Sivils, Kathy L, Vyse, Timothy J, Gaffney, Patrick M., Langefeld, Carl D, Jacob, Chaim O.
Publicado 2014

Context-dependent induction of autoimmunity by TNF signaling deficiency

por Quach, Tam D., Huang, Weiqing, Sahu, Ranjit, Diadhiou, Catherine M.M., Raparia, Chirag, Johnson, Roshawn, Leung, Tung Ming, Malkiel, Susan, Ricketts, Peta Gay, Gallucci, Stefania, Tükel, Çagla, Jacob, Chaim O., Lesser, Martin L., Zou, Yong-Rui, Davidson, Anne
Publicado 2022

Subphenotype mapping in systemic lupus erythematosus identifies multiple novel loci associated with circulating interferon alpha

por Kariuki, Silvia N, Ghodke-Puranik, Yogita, Dorschner, Jessica M, Chrabot, Beverly S, Kelly, Jennifer A, Tsao, Betty P, Kimberly, Robert P, Alarcón-Riquelme, Marta E, Jacob, Chaim O, Criswell, Lindsey A, Sivils, Kathy L, Langefeld, Carl D, Harley, John B, Skol, Andrew D, Niewold, Timothy B
Publicado 2014

Genetic Analysis of the Pathogenic Molecular Sub-phenotype Interferon Alpha Identifies Multiple Novel Loci Involved in Systemic Lupus Erythematosus

por Kariuki, Silvia N., Ghodke-Puranik, Yogita, Dorschner, Jessica M., Chrabot, Beverly S., Kelly, Jennifer A., Tsao, Betty P., Kimberly, Robert P., Alarcón-Riquelme, Marta E., Jacob, Chaim O., Criswell, Lindsey A., Sivils, Kathy L., Langefeld, Carl D., Harley, John B., Skol, Andrew D., Niewold, Timothy B.
Publicado 2014

Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes

por Taylor, Kimberly E., Chung, Sharon A., Graham, Robert R., Ortmann, Ward A., Lee, Annette T., Langefeld, Carl D., Jacob, Chaim O., Kamboh, M. Ilyas, Alarcón-Riquelme, Marta E., Tsao, Betty P., Moser, Kathy L., Gaffney, Patrick M., Harley, John B., Petri, Michelle, Manzi, Susan, Gregersen, Peter K., Behrens, Timothy W., Criswell, Lindsey A.
Publicado 2011

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

por Chung, Sharon A., Taylor, Kimberly E., Graham, Robert R., Nititham, Joanne, Lee, Annette T., Ortmann, Ward A., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Tsao, Betty P., Harley, John B., Gaffney, Patrick M., Moser, Kathy L., Petri, Michelle, Demirci, F. Yesim, Kamboh, M. Ilyas, Manzi, Susan, Gregersen, Peter K., Langefeld, Carl D., Behrens, Timothy W., Criswell, Lindsey A.
Publicado 2011

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

por Ramos, Paula S., Criswell, Lindsey A., Moser, Kathy L., Comeau, Mary E., Williams, Adrienne H., Pajewski, Nicholas M., Chung, Sharon A., Graham, Robert R., Zidovetzki, Raphael, Kelly, Jennifer A., Kaufman, Kenneth M., Jacob, Chaim O., Vyse, Timothy J., Tsao, Betty P., Kimberly, Robert P., Gaffney, Patrick M., Alarcón-Riquelme, Marta E., Harley, John B., Langefeld, Carl D.
Publicado 2011

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

por Raj, Prithvi, Rai, Ekta, Song, Ran, Khan, Shaheen, Wakeland, Benjamin E, Viswanathan, Kasthuribai, Arana, Carlos, Liang, Chaoying, Zhang, Bo, Dozmorov, Igor, Carr-Johnson, Ferdicia, Mitrovic, Mitja, Wiley, Graham B, Kelly, Jennifer A, Lauwerys, Bernard R, Olsen, Nancy J, Cotsapas, Chris, Garcia, Christine K, Wise, Carol A, Harley, John B, Nath, Swapan K, James, Judith A, Jacob, Chaim O, Tsao, Betty P, Pasare, Chandrashekhar, Karp, David R, Li, Quan Zhen, Gaffney, Patrick M, Wakeland, Edward K
Publicado 2016

Complement receptor 2 polymorphisms associated with systemic lupus erythematosus modulate alternative splicing

por Douglas, Katherine B., Windels, Daniel C., Zhao, Jian, Gadeliya, Agnessa V., Wu, Hui, Kaufman, Kenneth M., Harley, John B., Merrill, Joan, Kimberly, Robert P., Alarcón, Graciela S., Brown, Elizabeth E., Edberg, Jeffrey C., Ramsey-Goldman, Rosalind, Petri, Michelle, Reveille, John D., Vilá, Luis M., Gaffney, Patrick M., James, Judith A., Moser, Kathy L., Alarcón-Riquelme, Marta E., Vyse, Timothy J., Gilkeson, Gary S., Jacob, Chaim O., Ziegler, Julie T., Langefeld, Carl D., Ulgiati, Daniela, Tsao, Betty P., Boackle, Susan A.
Publicado 2009

The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

por Harley, Isaac T. W., Niewold, Timothy B., Stormont, Rebecca M., Kaufman, Kenneth M., Glenn, Stuart B., Franek, Beverly S., Kelly, Jennifer A., Kilpatrick, Jeffrey R., Hutchings, David, Divers, Jasmin, Bruner, Gail R., Edberg, Jeffrey C., McGwin, Gerald, Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá-Pérez, Luis M., Merrill, Joan T., Gilkeson, Gary S., Vyse, Timothy J., Alarcón-Riquelme, Marta E., Cho, Soo-Kyung, Jacob, Chaim O., Alarcón, Graciela S., Moser, Kathy L., Gaffney, Patrick M., Kimberly, Robert P., Bae, Sang-Cheol, Langefeld, Carl D., Harley, John B., Guthridge, Joel M., James, Judith A.
Publicado 2010

Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

por Hanscombe, Ken B, Morris, David L, Noble, Janelle A, Dilthey, Alexander T, Tombleson, Philip, Kaufman, Kenneth M, Comeau, Mary, Langefeld, Carl D, Alarcon-Riquelme, Marta E, Gaffney, Patrick M, Jacob, Chaim O, Sivils, Kathy L, Tsao, Betty P, Alarcon, Graciela S, Brown, Elizabeth E, Croker, Jennifer, Edberg, Jeff, Gilkeson, Gary, James, Judith A, Kamen, Diane L, Kelly, Jennifer A, McCune, Joseph, Merrill, Joan T, Petri, Michelle, Ramsey-Goldman, Rosalind, Reveille, John D, Salmon, Jane E, Scofield, Hal, Utset, Tammy, Wallace, Daniel J, Weisman, Michael H, Kimberly, Robert P, Harley, John B, Lewis, Cathryn M, Criswell, Lindsey A, Vyse, Timothy J
Publicado 2018

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

por Molineros, Julio E., Maiti, Amit K., Sun, Celi, Looger, Loren L., Han, Shizhong, Kim-Howard, Xana, Glenn, Stuart, Adler, Adam, Kelly, Jennifer A., Niewold, Timothy B., Gilkeson, Gary S., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Petri, Michelle, Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Freedman, Barry I., Tsao, Betty P., Criswell, Lindsey A., Jacob, Chaim O., Moore, Jason H., Vyse, Timothy J., Langefeld, Carl L., Guthridge, Joel M., Gaffney, Patrick M., Moser, Kathy L., Scofield, R. Hal, Alarcón-Riquelme, Marta E., Williams, Scott M., Merrill, Joan T., James, Judith A., Kaufman, Kenneth M., Kimberly, Robert P., Harley, John B., Nath, Swapan K.
Publicado 2013