MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants

por Cholewinski, Tomasz, Pereira, Diana, Moerland, Matthijs, Jacobs, Gabriel E.
Publicado 2021

Unsuspected serotonin toxicity in the ICU

por van Ewijk, Catharina E., Jacobs, Gabriel E., Girbes, Armand R. J.
Publicado 2016

A Study of the Effects of Electrode Number and Decoding Algorithm on Online EEG-Based BCI Behavioral Performance

por Meng, Jianjun, Edelman, Bradley J., Olsoe, Jaron, Jacobs, Gabriel, Zhang, Shuying, Beyko, Angeliki, He, Bin
Publicado 2018

PK/PD modeling of 5‐hydroxytryptophan (5‐HTP) challenge test with cortisol measurement in serum and saliva

por Guan, Zheng, Jacobs, Gabriel, van Pelt, Hans, Van Gerven, Joop M.A., Burggraaf, Jacobus, Zhao, Wei
Publicado 2020

Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

por Muehlan, Clemens, Brooks, Sander, Vaillant, Cedric, Meinel, Michael, Jacobs, Gabriël E., Zuiker, Rob G., Dingemanse, Jasper
Publicado 2022

Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery‐Åsberg Depression Rating Scale

por Otto, Marije E., Bergmann, Kirsten R., de Kam, Marieke L., Recourt, Kasper, Jacobs, Gabriël E., van Esdonk, Michiel J.
Publicado 2023

Breast tumor cell hybrids form spontaneously in vivo and contribute to breast tumor metastases

por Chitwood, Casey A., Dietzsch, Claire, Jacobs, Gabriel, McArdle, Tanner, Freeman, Brian T., Banga, Annanya, Noubissi, Felicite K., Ogle, Brenda M.
Publicado 2018

Central nervous system effects of TAK-653, an investigational alpha-amino-3-hydroxy-5-methyl-4-isoxazole receptor (AMPAR) positive allosteric modulator in healthy volunteers

por Dijkstra, Francis, O’Donnell, Patricio, Klaassen, Erica, Buhl, Derek, Asgharnejad, Mahnaz, Rosen, Laura, Zuiker, Rob, van Gerven, Joop, Jacobs, Gabriël
Publicado 2022

Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration–effect relations using the IB-de-risk tool

por Kwee, Caroline MB, van Gerven, Joop MA, Bongaerts, Fleur LP, Cath, Danielle C, Jacobs, Gabriël, Baas, Johanna MP, Groenink, Lucianne
Publicado 2022

The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder

por Recourt, Kasper, de Boer, Peter, Zuiker, Rob, Luthringer, Remy, Kent, Justine, van der Ark, Peter, Van Hove, Ilse, van Gerven, Joop, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Publicado 2019

Correction to: The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder

por Recourt, Kasper, de Boer, Peter, Zuiker, Rob, Luthringer, Remy, Kent, Justine, van der Ark, Peter, Van Hove, Ilse, van Gerven, Joop, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Publicado 2019

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

por Recourt, Kasper, de Boer, Peter, van der Ark, Peter, Benes, Heike, van Gerven, Joop M. A., Ceusters, Marc, van Nueten, Luc, Drevets, Wayne C., Bhatacharya, Anindya, Browning, Michael, Jacobs, Gabriel E.
Publicado 2023

A smartphone- and wearable-based biomarker for the estimation of unipolar depression severity

por Zhuparris, Ahnjili, Maleki, Ghobad, van Londen, Liesbeth, Koopmans, Ingrid, Aalten, Vincent, Yocarini, Iris E., Exadaktylos, Vasileios, van Hemert, Albert, Cohen, Adam, Gal, Pim, Doll, Robert-Jan, Groeneveld, Geert Jan, Jacobs, Gabriël, Kraaij, Wessel
Publicado 2023

The effects of intranasal esketamine on on-road driving performance in patients with major depressive disorder or persistent depressive disorder

por Dijkstra, Francis M, van de Loo, Aurora JAE, Abdulahad, Smedra, Bosma, Else R, Hartog, Mitch, Huls, Hendrikje, Kuijper, Dianne C, de Vries, Esther, Solanki, Bhavna, Singh, Jaskaran, Aluisio, Leah, Zannikos, Peter, Stuurman, Frederik E, Jacobs, Gabriël E, Verster, Joris C
Publicado 2022

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

por Salvadore, Giacomo, Bonaventure, Pascal, Shekhar, Anantha, Johnson, Philip L., Lord, Brian, Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Dugovic, Christine, Brooks, Sander, Zuiker, Rob, Bleys, Cathy, Tatikola, Kanaka, Remmerie, Bart, Jacobs, Gabriel E., Schruers, Koen, Moyer, John, Nash, Abigail, Van Nueten, Luc G. M., Drevets, Wayne C.
Publicado 2020

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

por O’Donnell, Patricio, Dijkstra, Francis M., Damar, Ugur, Quanhong, Lei, de Goede, Annika A., Xu, Lin, Pascual-Leone, Andres, Buhl, Derek L., Zuiker, Rob, Ruijs, Titia Q., Heuberger, Jules A. A. C., MacMullin, Paul, Lubell, Martin, Asgharnejad, Mahnaz, Murthy, Venkatesha, Rotenberg, Alexander, Jacobs, Gabriel E., Rosen, Laura
Publicado 2021

A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression

por Sverdlov, Oleksandr, Curcic, Jelena, Hannesdottir, Kristin, Gou, Liangke, De Luca, Valeria, Ambrosetti, Francesco, Zhang, Bingsong, Praestgaard, Jens, Vallejo, Vanessa, Dolman, Andrew, Gomez-Mancilla, Baltazar, Biliouris, Konstantinos, Deurinck, Mark, Cormack, Francesca, Anderson, John J., Bott, Nicholas T., Peremen, Ziv, Issachar, Gil, Laufer, Offir, Joachim, Dale, Jagesar, Raj R., Jongs, Niels, Kas, Martien J., Zhuparris, Ahnjili, Zuiker, Rob, Recourt, Kasper, Zuilhof, Zoë, Cha, Jang-Ho, Jacobs, Gabriel E.
Publicado 2021