MTORC1 signaling as a biomarker in major depressive disorder and its pharmacological modulation by novel rapid-acting antidepressants

por Cholewinski, Tomasz, Pereira, Diana, Moerland, Matthijs, Jacobs, Gabriel E.
Publicado 2021

Unsuspected serotonin toxicity in the ICU

por van Ewijk, Catharina E., Jacobs, Gabriel E., Girbes, Armand R. J.
Publicado 2016

Driving Performance after Bedtime Administration of Daridorexant, Assessed in a Sensitive Simulator

por Muehlan, Clemens, Brooks, Sander, Vaillant, Cedric, Meinel, Michael, Jacobs, Gabriël E., Zuiker, Rob G., Dingemanse, Jasper
Publicado 2022

Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery‐Åsberg Depression Rating Scale

por Otto, Marije E., Bergmann, Kirsten R., de Kam, Marieke L., Recourt, Kasper, Jacobs, Gabriël E., van Esdonk, Michiel J.
Publicado 2023

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

por Recourt, Kasper, de Boer, Peter, van der Ark, Peter, Benes, Heike, van Gerven, Joop M. A., Ceusters, Marc, van Nueten, Luc, Drevets, Wayne C., Bhatacharya, Anindya, Browning, Michael, Jacobs, Gabriel E.
Publicado 2023

The effects of intranasal esketamine on on-road driving performance in patients with major depressive disorder or persistent depressive disorder

por Dijkstra, Francis M, van de Loo, Aurora JAE, Abdulahad, Smedra, Bosma, Else R, Hartog, Mitch, Huls, Hendrikje, Kuijper, Dianne C, de Vries, Esther, Solanki, Bhavna, Singh, Jaskaran, Aluisio, Leah, Zannikos, Peter, Stuurman, Frederik E, Jacobs, Gabriël E, Verster, Joris C
Publicado 2022

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

por Salvadore, Giacomo, Bonaventure, Pascal, Shekhar, Anantha, Johnson, Philip L., Lord, Brian, Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Dugovic, Christine, Brooks, Sander, Zuiker, Rob, Bleys, Cathy, Tatikola, Kanaka, Remmerie, Bart, Jacobs, Gabriel E., Schruers, Koen, Moyer, John, Nash, Abigail, Van Nueten, Luc G. M., Drevets, Wayne C.
Publicado 2020

Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation

por O’Donnell, Patricio, Dijkstra, Francis M., Damar, Ugur, Quanhong, Lei, de Goede, Annika A., Xu, Lin, Pascual-Leone, Andres, Buhl, Derek L., Zuiker, Rob, Ruijs, Titia Q., Heuberger, Jules A. A. C., MacMullin, Paul, Lubell, Martin, Asgharnejad, Mahnaz, Murthy, Venkatesha, Rotenberg, Alexander, Jacobs, Gabriel E., Rosen, Laura
Publicado 2021

A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression

por Sverdlov, Oleksandr, Curcic, Jelena, Hannesdottir, Kristin, Gou, Liangke, De Luca, Valeria, Ambrosetti, Francesco, Zhang, Bingsong, Praestgaard, Jens, Vallejo, Vanessa, Dolman, Andrew, Gomez-Mancilla, Baltazar, Biliouris, Konstantinos, Deurinck, Mark, Cormack, Francesca, Anderson, John J., Bott, Nicholas T., Peremen, Ziv, Issachar, Gil, Laufer, Offir, Joachim, Dale, Jagesar, Raj R., Jongs, Niels, Kas, Martien J., Zhuparris, Ahnjili, Zuiker, Rob, Recourt, Kasper, Zuilhof, Zoë, Cha, Jang-Ho, Jacobs, Gabriel E.
Publicado 2021