DNA Double Strand Breaks Occur Independent of AID in Hypermutating Ig Genes

por Bross, Linda, Jacobs, Heinz
Publicado 2003

Mutating for Good: DNA Damage Responses During Somatic Hypermutation

por Pilzecker, Bas, Jacobs, Heinz
Publicado 2019

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

por Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Jacobs, Heinz
Publicado 2019

Signals for antigen-independent differentiation of memory CD8(+) T cells

por Kwesi-Maliepaard, Eliza Mari, Jacobs, Heinz, van Leeuwen, Fred
Publicado 2021

DNA Double-Strand Breaks: Prior to but not Sufficient in Targeting Hypermutation

por Bross, Linda, Muramatsu, Masamichi, Kinoshita, Kazuo, Honjo, Tasuku, Jacobs, Heinz
Publicado 2002

Chromosomal Rearrangements and Chromothripsis: The Alternative End Generation Model

por de Groot, Daniel, Spanjaard, Aldo, Hogenbirk, Marc A., Jacobs, Heinz
Publicado 2023

Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA

por Langerak, Petra, Nygren, Anders O. H., Schouten, Jan P., Jacobs, Heinz
Publicado 2005

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation

por Krijger, Peter H.L., Langerak, Petra, van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2009

The Fanconi Anemia Core Complex Is Dispensable during Somatic Hypermutation and Class Switch Recombination

por Krijger, Peter H. L., Wit, Niek, van den Berk, Paul C. M., Jacobs, Heinz
Publicado 2010

Lysine Residue 185 of Rad1 Is a Topological but Not a Functional Counterpart of Lysine Residue 164 of PCNA

por Wit, Niek, Krijger, Peter H. L., van den Berk, Paul C. M., Jacobs, Heinz
Publicado 2011

Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice

por Jansen, Jacob G., Langerak, Petra, Tsaalbi-Shtylik, Anastasia, van den Berk, Paul, Jacobs, Heinz, de Wind, Niels
Publicado 2006

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigen(K164R) mutant mice

por Langerak, Petra, Krijger, Peter H.L., Heideman, Marinus R., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2008

Redundancy of mammalian Y family DNA polymerases in cellular responses to genomic DNA lesions induced by ultraviolet light

por Jansen, Jacob G., Temviriyanukul, Piya, Wit, Niek, Delbos, Frédéric, Reynaud, Claude-Agnès, Jacobs, Heinz, de Wind, Niels
Publicado 2014

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNA(K164) modification

por Langerak, Petra, Nygren, Anders O.H., Krijger, Peter H.L., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2007

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice

por Jacobs, Heinz, Krimpenfort, Paul, Haks, Mariëlle, Allen, John, Blom, Bianca, Démollière, Corinne, Kruisbeek, Ada, Spits, Hergen, Berns, Anton
Publicado 1999

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

por Jansen, Jacob G., Tsaalbi-Shtylik, Anastasia, Langerak, Petra, Calléja, Fabienne, Meijers, Caro M., Jacobs, Heinz, de Wind, Niels
Publicado 2005

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis

por Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Pritchard, Colin, Blomberg, Olga S., Huijbers, Ivo J., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2016

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype

por Shah, Ronak, van den Berk, Paul C. M., Pritchard, Colin E. J., Song, Ji-Ying, Kreft, Maaike, Pilzecker, Bas, Jacobs, Heinz
Publicado 2023

Differential Programming of B Cells in AID Deficient Mice

por Hogenbirk, Marc A., Heideman, Marinus R., Velds, Arno, van den Berk, Paul CM., Kerkhoven, Ron M., van Steensel, Bas, Jacobs, Heinz
Publicado 2013

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage

por Wit, Niek, Buoninfante, Olimpia Alessandra, van den Berk, Paul C.M., Jansen, Jacob G., Hogenbirk, Marc A., de Wind, Niels, Jacobs, Heinz
Publicado 2015