Novel insights on interactions between folate and lipid metabolism

por da Silva, Robin P, Kelly, Karen B, Al Rajabi, Ala, Jacobs, René L
Publicado 2014

Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice

por Wu, Gengshu, Zhang, Liyan, Li, Tete, Lopaschuk, Gary, Vance, Dennis E., Jacobs, René L.
Publicado 2012

Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver

por Lian, Jihong, van der Veen, Jelske N., Watts, Russell, Jacobs, René L., Lehner, Richard
Publicado 2021

Liver and plasma lipid changes induced by cyclic fatty acid monomers from heated vegetable oil in the rat

por Mboma, Jean, Leblanc, Nadine, Wan, Sereana, Jacobs, René L., Tchernof, André, Dubé, Pascal, Angers, Paul, Jacques, Hélène
Publicado 2018

Feeding a Mixture of Choline Forms to Lactating Dams Improves the Development of the Immune System in Sprague-Dawley Rat Offspring

por Richard, Caroline, Lewis, Erin D., Goruk, Susan, Wadge, Emily, Curtis, Jonathan M., Jacobs, René L., Field, Catherine J.
Publicado 2017

Feeding a Mixture of Choline Forms during Lactation Improves Offspring Growth and Maternal Lymphocyte Response to Ex Vivo Immune Challenges

por Lewis, Erin D., Richard, Caroline, Goruk, Susan, Wadge, Emily, Curtis, Jonathan M., Jacobs, René L., Field, Catherine J.
Publicado 2017

Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis

por Uehara, Kahealani, Sostre-Colón, Jaimarie, Gavin, Matthew, Santoleri, Dominic, Leonard, Kelly-Ann, Jacobs, René L., Titchenell, Paul M.
Publicado 2022

Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase

por van der Veen, Jelske N., Lingrell, Susanne, Gao, Xia, Takawale, Abhijit, Kassiri, Zamaneh, Vance, Dennis E., Jacobs, René L.
Publicado 2017

Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet

por Wan, Sereana, Kuipers, Folkert, Havinga, Rick, Ando, Hiromi, Vance, Dennis E., Jacobs, René L., van der Veen, Jelske N.
Publicado 2019

Corrigendum: Egg-phosphatidylcholine attenuates T-cell dysfunction in high-fat diet fed male Wistar rats

por Azarcoya-Barrera, Jessy, Wollin, Bethany, Veida-Silva, Hellen, Makarowski, Alexander, Goruk, Susan, Field, Catherine J., Jacobs, René L., Richard, Caroline
Publicado 2023

Egg-Phosphatidylcholine Attenuates T-Cell Dysfunction in High-Fat Diet Fed Male Wistar Rats

por Azarcoya-Barrera, Jessy, Wollin, Bethany, Veida-Silva, Hellen, Makarowski, Alexander, Goruk, Susan, Field, Catherine J., Jacobs, René L., Richard, Caroline
Publicado 2022

Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese mice

por Hetherington, Alexandra M., Sawyez, Cynthia G., Sutherland, Brian G., Robson, Debra L., Arya, Rigya, Kelly, Karen, Jacobs, René L., Borradaile, Nica M.
Publicado 2016

Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice

por Christensen, Karen E., Malysheva, Olga V., Carlin, Stephanie, Matias, Fernando, MacFarlane, Amanda J., Jacobs, René L., Caudill, Marie A., Rozen, Rima
Publicado 2021

Excess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed Rats

por Kelly, Karen B., Kennelly, John P., Ordonez, Marta, Nelson, Randal, Leonard, Kelly, Stabler, Sally, Gomez-Muñoz, Antonio, Field, Catherine J., Jacobs, René L.
Publicado 2016

Intestinal Phospholipid Disequilibrium Initiates an ER Stress Response That Drives Goblet Cell Necroptosis and Spontaneous Colitis in Mice

por Kennelly, John P., Carlin, Stephanie, Ju, Tingting, van der Veen, Jelske N., Nelson, Randal C., Buteau, Jean, Thiesen, Aducio, Richard, Caroline, Willing, Ben P., Jacobs, René L.
Publicado 2020

Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease

por Wilson, Rachel B., Zhang, Richard, Chen, Yun Jin, Peters, Kia M., Sawyez, Cynthia G., Sutherland, Brian G., Patel, Krisha, Kennelly, John P., Leonard, Kelly-Ann, Jacobs, René L., Wang, Rennian, Borradaile, Nica M.
Publicado 2020

Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

por Koonen, Debby P.Y., Sung, Miranda M.Y., Kao, Cindy K.C., Dolinsky, Vernon W., Koves, Timothy R., Ilkayeva, Olga, Jacobs, René L., Vance, Dennis E., Light, Peter E., Muoio, Deborah M., Febbraio, Maria, Dyck, Jason R.B.
Publicado 2010

Late-onset megaconial myopathy in mice lacking group I Paks

por Joseph, Giselle A., Hung, Margaret, Goel, Aviva J., Hong, Mingi, Rieder, Marysia-Kolbe, Beckmann, Noam D., Serasinghe, Madhavika N., Chipuk, Jerry E., Devarakonda, Parvathi M., Goldhamer, David J., Aldana-Hernandez, Paulina, Curtis, Jonathan, Jacobs, René L., Krauss, Robert S.
Publicado 2019

Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease

por Sheedfar, Fareeba, Sung, Miranda MY, Aparicio-Vergara, Marcela, Kloosterhuis, Niels J, Miquilena-Colina, Maria Eugenia, Vargas-Castrillón, Javier, Febbraio, Maria, Jacobs, René L, de Bruin, Alain, Vinciguerra, Manlio, García-Monzón, Carmelo, Hofker, Marten H, Dyck, Jason RB, Koonen, Debby PY
Publicado 2014

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

por Ayer, Anita, Fazakerley, Daniel J., Suarna, Cacang, Maghzal, Ghassan J., Sheipouri, Diba, Lee, Kevin J., Bradley, Michelle C., Fernández-del-Rio, Lucía, Tumanov, Sergey, Kong, Stephanie MY., van der Veen, Jelske N., Yang, Andrian, Ho, Joshua W.K., Clarke, Steven G., James, David E., Dawes, Ian W., Vance, Dennis E., Clarke, Catherine F., Jacobs, René L., Stocker, Roland
Publicado 2021