Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding

por Neef, Daniel W., Jaeger, Alex M., Thiele, Dennis J.
Publicado 2013

Structures of HSF2 Reveal Mechanisms for Differential Regulation of Human Heat Shock Factors

por Jaeger, Alex M., Pemble, Charles W., Sistonen, Lea, Thiele, Dennis J.
Publicado 2016

Navigational Bronchoscopy for Early Lung Cancer: A Road to Therapy

por Khan, Kashif Ali, Nardelli, Pietro, Jaeger, Alex, O’Shea, Conor, Cantillon-Murphy, Padraig, Kennedy, Marcus P.
Publicado 2016

Multiscale profiling of protease activity in cancer

por Amini, Ava P., Kirkpatrick, Jesse D., Wang, Cathy S., Jaeger, Alex M., Su, Susan, Naranjo, Santiago, Zhong, Qian, Cabana, Christina M., Jacks, Tyler, Bhatia, Sangeeta N.
Publicado 2022

Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease

por Gomez-Pastor, Rocio, Burchfiel, Eileen T., Neef, Daniel W., Jaeger, Alex M., Cabiscol, Elisa, McKinstry, Spencer U., Doss, Argenia, Aballay, Alejandro, Lo, Donald C., Akimov, Sergey S., Ross, Christopher A., Eroglu, Cagla, Thiele, Dennis J.
Publicado 2017

Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

por Genshaft, Alex S, Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.
Publicado 2021

Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

por Genshaft, Alex S., Ziegler, Carly G. K., Tzouanas, Constantine N., Mead, Benjamin E., Jaeger, Alex M., Navia, Andrew W., King, Ryan P., Mana, Miyeko D., Huang, Siyi, Mitsialis, Vanessa, Snapper, Scott B., Yilmaz, Ömer H., Jacks, Tyler, Van Humbeck, Jeffrey F., Shalek, Alex K.
Publicado 2021

Low neoantigen expression and poor T-cell priming underlie early immune escape in colorectal cancer

por Westcott, Peter M K, Sacks, Nathan J, Schenkel, Jason M, Ely, Zackery A, Smith, Olivia, Hauck, Haley, Jaeger, Alex M, Zhang, Daniel, Backlund, Coralie M, Beytagh, Mary C, Patten, JJ, Elbashir, Ryan, Eng, George, Irvine, Darrell J, Yilmaz, Omer H, Jacks, Tyler
Publicado 2021

Mismatch repair deficiency is not sufficient to elicit tumor immunogenicity

por Westcott, Peter M. K., Muyas, Francesc, Hauck, Haley, Smith, Olivia C., Sacks, Nathan J., Ely, Zackery A., Jaeger, Alex M., Rideout, William M., Zhang, Daniel, Bhutkar, Arjun, Beytagh, Mary C., Canner, David A., Jaramillo, Grissel C., Bronson, Roderick T., Naranjo, Santiago, Jin, Abbey, Patten, J. J., Cruz, Amanda M., Shanahan, Sean-Luc, Cortes-Ciriano, Isidro, Jacks, Tyler
Publicado 2023

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

por Raghavan, Srivatsan, Winter, Peter S., Navia, Andrew W., Williams, Hannah L., DenAdel, Alan, Lowder, Kristen E., Galvez-Reyes, Jennyfer, Kalekar, Radha L., Mulugeta, Nolawit, Kapner, Kevin S., Raghavan, Manisha S., Borah, Ashir A., Liu, Nuo, Väyrynen, Sara A., Costa, Andressa Dias, Ng, Raymond W.S., Wang, Junning, Hill, Emma K., Ragon, Dorisanne Y., Brais, Lauren K., Jaeger, Alex M., Spurr, Liam F., Li, Yvonne Y., Cherniack, Andrew D., Booker, Matthew A., Cohen, Elizabeth F., Tolstorukov, Michael Y., Wakiro, Isaac, Rotem, Asaf, Johnson, Bruce E., McFarland, James M., Sicinska, Ewa T., Jacks, Tyler E., Sullivan, Ryan J., Shapiro, Geoffrey I., Clancy, Thomas E., Perez, Kimberly, Rubinson, Douglas A., Ng, Kimmie, Cleary, James M., Crawford, Lorin, Manalis, Scott R., Nowak, Jonathan A., Wolpin, Brian M., Hahn, William C., Aguirre, Andrew J., Shalek, Alex K.
Publicado 2021