Mineralocorticoid Receptors in the Pathophysiology of Vascular Inflammation and Atherosclerosis

por Moss, Mary E., Jaffe, Iris Z.
Publicado 2015

ROCK and Rolling Towards Predicting BCR-ABL Kinase Inhibitor-Induced Vascular Toxicity

por Upshaw, Jenica N., Travers, Richard, Jaffe, Iris Z.
Publicado 2022

Mineralocorticoid Receptor–Mediated Vascular Insulin Resistance: An Early Contributor to Diabetes-Related Vascular Disease?

por Bender, Shawn B., McGraw, Adam P., Jaffe, Iris Z., Sowers, James R.
Publicado 2013

Development and implementation of an integrated preclinical atherosclerosis database

por Xiang, Rachel, Wang, Yihua, Shuey, Megan M., Carvajal, Brigett, Wells, Quinn S., Beckman, Joshua A., Jaffe, Iris Z.
Publicado 2023

No Significant Role for Smooth Muscle Cell Mineralocorticoid Receptors in Atherosclerosis in the Apolipoprotein-E Knockout Mouse Model

por Moss, M. Elizabeth, DuPont, Jennifer J., Iyer, Surabhi L., McGraw, Adam P., Jaffe, Iris Z.
Publicado 2018

Selective deletion of endothelial mineralocorticoid receptor protects from vascular dysfunction in sodium-restricted female mice

por Faulkner, Jessica L., Lluch, Emily, Kennard, Simone, Antonova, Galina, Jaffe, Iris Z., Belin de Chantemèle, Eric J.
Publicado 2020

Differential vascular endothelial cell toxicity of established and novel BCR-ABL tyrosine kinase inhibitors

por Wang, Yihua, Travers, Richard J., Farrell, Alanna, Lu, Qing, Bays, Jennifer L., Stepanian, Alec, Chen, Christopher, Jaffe, Iris Z.
Publicado 2023

Endothelial mineralocorticoid receptor contributes to systolic dysfunction induced by pressure overload without modulating cardiac hypertrophy or inflammation

por Salvador, Ane M., Moss, M. Elizabeth, Aronovitz, Mark, Mueller, Kathleen B., Blanton, Robert M., Jaffe, Iris Z., Alcaide, Pilar
Publicado 2017

Short-Term Administration of Serelaxin Produces Predominantly Vascular Benefits in the Angiotensin II/L-NAME Chronic Heart Failure Model

por McCarthy, Joseph C., Aronovitz, Mark, DuPont, Jennifer J., Calamaras, Timothy D., Jaffe, Iris Z., Blanton, Robert M.
Publicado 2017

Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging

por Gorini, Stefania, Kim, Seung Kyum, Infante, Marco, Mammi, Caterina, La Vignera, Sandro, Fabbri, Andrea, Jaffe, Iris Z., Caprio, Massimiliano
Publicado 2019

Sex‐Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors

por Davel, Ana P., Lu, Qing, Moss, M. Elizabeth, Rao, Sitara, Anwar, Imran J., DuPont, Jennifer J., Jaffe, Iris Z.
Publicado 2018

Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism

por McGraw, Adam P., Bagley, Jessamyn, Chen, Wei‐Sheng, Galayda, Carol, Nickerson, Heather, Armani, Andrea, Caprio, Massimiliano, Carmeliet, Peter, Jaffe, Iris Z.
Publicado 2013

Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by β-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue

por Victorio, Jamaira A., Clerici, Stefano P., Palacios, Roberto, Alonso, María J., Vassallo, Dalton V., Jaffe, Iris Z., Rossoni, Luciana V., Davel, Ana P.
Publicado 2016

Comparative Transcriptomics of Ex Vivo, Patient-Derived Endothelial Cells Reveals Novel Pathways Associated With Type 2 Diabetes Mellitus

por Beckman, Joshua A., Doherty, Sean P., Feldman, Zachary B., Banks, Emily S., Moslehi, Javid, Jaffe, Iris Z., Hamburg, Naomi M., Sheng, Quanhu, Brown, Jonathan D.
Publicado 2019

Gene expression in term placentas is regulated more by spinal or epidural anesthesia than by late-onset preeclampsia or gestational diabetes mellitus

por Lekva, Tove, Lyle, Robert, Roland, Marie Cecilie Paasche, Friis, Camilla, Bianchi, Diana W., Jaffe, Iris Z., Norwitz, Errol R., Bollerslev, Jens, Henriksen, Tore, Ueland, Thor
Publicado 2016

Intercellular Adhesion Molecule 1 Regulates Left Ventricular Leukocyte Infiltration, Cardiac Remodeling, and Function in Pressure Overload–Induced Heart Failure

por Salvador, Ane M., Nevers, Tania, Velázquez, Francisco, Aronovitz, Mark, Wang, Bonnie, Abadía Molina, Ana, Jaffe, Iris Z., Karas, Richard H., Blanton, Robert M., Alcaide, Pilar
Publicado 2016

Vascular cell-specific roles of mineralocorticoid receptors in pulmonary hypertension

por Menon, Divya P., Qi, Guanming, Kim, Seung K., Moss, M. Elizabeth, Penumatsa, Krishna C., Warburton, Rod R., Toksoz, Deniz, Wilson, Jamie, Hill, Nicholas S., Jaffe, Iris Z., Preston, Ioana R.
Publicado 2021

Direct Regulation of Blood Pressure by Smooth Muscle Cell Mineralocorticoid Receptors

por McCurley, Amy, Pires, Paulo W., Bender, Shawn B., Aronovitz, Mark, Zhao, Michelle J., Metzger, Daniel, Chambon, Pierre, Hill, Michael A., Dorrance, Anne M., Mendelsohn, Michael E., Jaffe, Iris Z.
Publicado 2012

Distinct Effects of Unfractionated Heparin versus Bivalirudin on Circulating Angiogenic Peptides

por Kapur, Navin K., Shenoy, Chetan, Yunis, Adil A., Mohammad, Najwa N., Wilson, Szuhuei, Paruchuri, Vikram, Mackey, Emily E., Qiao, Xiaoying, Shah, Ameer, Esposito, Michele L., Karas, Richard H., Jaffe, Iris Z.
Publicado 2012

Reducing Endoglin Activity Limits Calcineurin and TRPC‐6 Expression and Improves Survival in a Mouse Model of Right Ventricular Pressure Overload

por Kapur, Navin K., Qiao, Xiaoying, Paruchuri, Vikram, Mackey, Emily E., Daly, Gerard H., Ughreja, Keshan, Morine, Kevin J., Levine, Jonathan, Aronovitz, Mark J., Hill, Nicholas S., Jaffe, Iris Z., Letarte, Michelle, Karas, Richard H.
Publicado 2014