Folding versus aggregation: Polypeptide conformations on competing pathways

por Jahn, Thomas R., Radford, Sheena E.
Publicado 2008

Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo

por Sowade, Ramona F., Jahn, Thomas R.
Publicado 2017

A Common β-Sheet Architecture Underlies in Vitro and in Vivo β(2)-Microglobulin Amyloid Fibrils

por Jahn, Thomas R., Tennent, Glenys A., Radford, Sheena E.
Publicado 2008

Identification of cis-acting determinants mediating the unconventional secretion of tau

por Katsinelos, Taxiarchis, McEwan, William A., Jahn, Thomas R., Nickel, Walter
Publicado 2021

HDX-ESI-MS Reveals Enhanced Conformational Dynamics of the Amyloidogenic Protein β(2)-Microglobulin upon Release from the MHC-1

por Hodkinson, John P., Jahn, Thomas R., Radford, Sheena E., Ashcroft, Alison E.
Publicado 2009

Reticulon-like-1, the Drosophila orthologue of the Hereditary Spastic Paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons

por O'Sullivan, Niamh C., Jahn, Thomas R., Reid, Evan, O'Kane, Cahir J.
Publicado 2012

The Drosophila KIF1A Homolog unc-104 Is Important for Site-Specific Synapse Maturation

por Zhang, Yao V., Hannan, Shabab B., Stapper, Zeenna A., Kern, Jeannine V., Jahn, Thomas R., Rasse, Tobias M.
Publicado 2016

The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization

por Zhang, Yao V., Hannan, Shabab B., Kern, Jeannine V., Stanchev, Doychin T., Koç, Baran, Jahn, Thomas R., Rasse, Tobias M.
Publicado 2017

Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease

por Jahn, Thomas R., Kohlhoff, Kai J., Scott, Michael, Tartaglia, Gian Gaetano, Lomas, David A., Dobson, Christopher M., Vendruscolo, Michele, Crowther, Damian C.
Publicado 2011

N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain

por Schlegel, Kerstin, Awwad, Khader, Heym, Roland G., Holzinger, David, Doell, Annika, Barghorn, Stefan, Jahn, Thomas R., Klein, Corinna, Mordashova, Yulia, Schulz, Michael, Gasparini, Laura
Publicado 2019

Globular Tetramers of β(2)-Microglobulin Assemble into Elaborate Amyloid Fibrils

por White, Helen E., Hodgkinson, Julie L., Jahn, Thomas R., Cohen-Krausz, Sara, Gosal, Walraj S., Müller, Shirley, Orlova, Elena V., Radford, Sheena E., Saibil, Helen R.
Publicado 2009

Expression in Drosophila of Tandem Amyloid β Peptides Provides Insights into Links between Aggregation and Neurotoxicity

por Speretta, Elena, Jahn, Thomas R., Tartaglia, Gian Gaetano, Favrin, Giorgio, Barros, Teresa P., Imarisio, Sara, Lomas, David A., Luheshi, Leila M., Crowther, Damian C., Dobson, Christopher M.
Publicado 2012

Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5 in Drosophila

por Zhu, Jun-yi, Hannan, Shabab B., Dräger, Nina M., Vereshchagina, Natalia, Krahl, Ann-Christin, Fu, Yulong, Elliott, Christopher J.H., Han, Zhe, Jahn, Thomas R., Rasse, Tobias M.
Publicado 2021

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

por Nachman, Eliana, Wentink, Anne S., Madiona, Karine, Bousset, Luc, Katsinelos, Taxiarchis, Allinson, Kieren, Kampinga, Harm, McEwan, William A., Jahn, Thomas R., Melki, Ronald, Mogk, Axel, Bukau, Bernd, Nussbaum-Krammer, Carmen
Publicado 2020

Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model

por Manos, Justine D., Preiss, Christina N., Venkat, Nandini, Tamm, Joseph, Reinhardt, Peter, Kwon, Taekyung, Wu, Jessica, Winter, Allison D., Jahn, Thomas R., Yanamandra, Kiran, Titterton, Katherine, Karran, Eric, Langlois, Xavier
Publicado 2021