Development of a novel stability indicating RP-HPLC method for quantification of Connexin43 mimetic peptide and determination of its degradation kinetics in biological fluids

por Bisht, Rohit, Rupenthal, Ilva D., Sreebhavan, Sreevalsan, Jaiswal, Jagdish K.
Publicado 2017

Efficacy of Providing the PI3K p110α Inhibitor BYL719 (Alpelisib) to Middle-Aged Mice in Their Diet

por Hedges, Christopher P., Boix, Jordi, Jaiswal, Jagdish K., Shetty, Bhoopika, Shepherd, Peter R., Merry, Troy L.
Publicado 2021

An agent-based model for drug-radiation interactions in the tumour microenvironment: Hypoxia-activated prodrug SN30000 in multicellular tumour spheroids

por Mao, Xinjian, McManaway, Sarah, Jaiswal, Jagdish K., Patel, Priyanka B., Wilson, William R., Hicks, Kevin O., Bogle, Gib
Publicado 2018

Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative

por Reynisson, Jóhannes, Jaiswal, Jagdish K., Barker, David, D’mello, Stacey A. N., Denny, William A., Baguley, Bruce C., Leung, Euphemia Y.
Publicado 2016

Diarylthiophenes as inhibitors of the pore-forming protein perforin

por Miller, Christian K., Huttunen, Kristiina M., Denny, William A., Jaiswal, Jagdish K., Ciccone, Annette, Browne, Kylie A., Trapani, Joseph A., Spicer, Julie A.
Publicado 2016

Benzenesulphonamide inhibitors of the cytolytic protein perforin

por Spicer, Julie A., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Huttunen, Kristiina M., Jaiswal, Jagdish K., Denny, William A., Akhlaghi, Hedieh, Browne, Kylie A., Trapani, Joseph A.
Publicado 2017

Substituted arylsulphonamides as inhibitors of perforin-mediated lysis

por Spicer, Julie A., Miller, Christian K., O'Connor, Patrick D., Jose, Jiney, Huttunen, Kristiina M., Jaiswal, Jagdish K., Denny, William A., Akhlaghi, Hedieh, Browne, Kylie A., Trapani, Joseph A.
Publicado 2017

Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice

por Gu, Yongchuan, Chang, Tony T.-A., Wang, Jingli, Jaiswal, Jagdish K., Edwards, David, Downes, Noel J., Liyanage, H. D. Sarath, Lynch, Courtney R. H., Pruijn, Frederik B., Hickey, Anthony J. R., Hay, Michael P., Wilson, William R., Hicks, Kevin O.
Publicado 2017

Preclinical Activity and Pharmacokinetic/Pharmacodynamic Relationship for a Series of Novel Benzenesulfonamide Perforin Inhibitors

por Gartlan, Kate H., Jaiswal, Jagdish K., Bull, Matthew R., Akhlaghi, Hedieh, Sutton, Vivien R., Alexander, Kylie A., Chang, Karshing, Hill, Geoffrey R., Miller, Christian K., O’Connor, Patrick D., Jose, Jiney, Trapani, Joseph A., Charman, Susan A., Spicer, Julie A., Jamieson, Stephen M. F.
Publicado 2022