Correlative Light and Electron Microscopy (CLEM) Analysis of Nuclear Reorganization Induced by Clustered DNA Damage Upon Charged Particle Irradiation

por Tonnemacher, Susanne, Eltsov, Mikhail, Jakob, Burkhard
Publicado 2020

Editorial: DNA damage response in the context of chromatin

por Zong, Dali, Jakob, Burkhard, Lundholm, Lovisa
Publicado 2023

Application of Fluorescence Lifetime Imaging Microscopy of DNA Binding Dyes to Assess Radiation-Induced Chromatin Compaction Changes

por Abdollahi, Elham, Taucher-Scholz, Gisela, Jakob, Burkhard
Publicado 2018

ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells

por Becker, Annabelle, Durante, Marco, Taucher-Scholz, Gisela, Jakob, Burkhard
Publicado 2014

O-GlcNAcylation Affects the Pathway Choice of DNA Double-Strand Break Repair

por Averbek, Sera, Jakob, Burkhard, Durante, Marco, Averbeck, Nicole B.
Publicado 2021

Induction and Processing of the Radiation-Induced Gamma-H2AX Signal and Its Link to the Underlying Pattern of DSB: A Combined Experimental and Modelling Study

por Tommasino, Francesco, Friedrich, Thomas, Jakob, Burkhard, Meyer, Barbara, Durante, Marco, Scholz, Michael
Publicado 2015

Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA–PK

por Meyer, Barbara, Voss, Kay-Obbe, Tobias, Frank, Jakob, Burkhard, Durante, Marco, Taucher-Scholz, Gisela
Publicado 2013

Differential Repair Protein Recruitment at Sites of Clustered and Isolated DNA Double-Strand Breaks Produced by High-Energy Heavy Ions

por Jakob, Burkhard, Dubiak-Szepietowska, Monika, Janiel, Ellen, Schmidt, Alina, Durante, Marco, Taucher-Scholz, Gisela
Publicado 2020

Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation

por Goetting, Isabell, Larafa, Safa, Eul, Katharina, Kunin, Mikhail, Jakob, Burkhard, Matschke, Johann, Jendrossek, Verena
Publicado 2022

The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells

por Averbeck, Nicole B., Barent, Carina, Jakob, Burkhard, Syzonenko, Tatyana, Durante, Marco, Taucher-Scholz, Gisela
Publicado 2022

Spatiotemporal Dynamics of Early DNA Damage Response Proteins on Complex DNA Lesions

por Tobias, Frank, Löb, Daniel, Lengert, Nicor, Durante, Marco, Drossel, Barbara, Taucher-Scholz, Gisela, Jakob, Burkhard
Publicado 2013

Reduced contribution of thermally labile sugar lesions to DNA double strand break formation after exposure to heavy ions

por Singh, Satyendra K, Bencsik-Theilen, Alena, Mladenov, Emil, Jakob, Burkhard, Taucher-Scholz, Gisela, Iliakis, George
Publicado 2013

A matter of space: how the spatial heterogeneity in energy deposition determines the biological outcome of radiation exposure

por Baiocco, Giorgio, Bartzsch, Stefan, Conte, Valeria, Friedrich, Thomas, Jakob, Burkhard, Tartas, Adrianna, Villagrasa, Carmen, Prise, Kevin M.
Publicado 2022

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin

por Jakob, Burkhard, Splinter, Jörn, Conrad, Sandro, Voss, Kay-Obbe, Zink, Daniele, Durante, Marco, Löbrich, Markus, Taucher-Scholz, Gisela
Publicado 2011

X-ray irradiation activates K(+) channels via H(2)O(2) signaling

por Gibhardt, Christine S., Roth, Bastian, Schroeder, Indra, Fuck, Sebastian, Becker, Patrick, Jakob, Burkhard, Fournier, Claudia, Moroni, Anna, Thiel, Gerhard
Publicado 2015

X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca(2+) entry and NFAT activation

por Tandl, Dominique, Sponagel, Tim, Alansary, Dalia, Fuck, Sebastian, Smit, Timo, Hehlgans, Stephanie, Jakob, Burkhard, Fournier, Claudia, Niemeyer, Barbara A., Rödel, Franz, Roth, Bastian, Moroni, Anna, Thiel, Gerhard
Publicado 2022

Autophosphorylation of DNA-PK(CS) regulates its dynamics at DNA double-strand breaks

por Uematsu, Naoya, Weterings, Eric, Yano, Ken-ichi, Morotomi-Yano, Keiko, Jakob, Burkhard, Taucher-Scholz, Gisela, Mari, Pierre-Olivier, van Gent, Dik C., Chen, Benjamin P.C., Chen, David J.
Publicado 2007

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase

por Lee, Kyung-Jong, Saha, Janapriya, Sun, Jingxin, Fattah, Kazi R., Wang, Shu-Chi, Jakob, Burkhard, Chi, Linfeng, Wang, Shih-Ya, Taucher-Scholz, Gisela, Davis, Anthony J., Chen, David J.
Publicado 2016

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

por Kijas, Amanda W., Lim, Yi Chieh, Bolderson, Emma, Cerosaletti, Karen, Gatei, Magtouf, Jakob, Burkhard, Tobias, Frank, Taucher-Scholz, Gisela, Gueven, Nuri, Oakley, Greg, Concannon, Patrick, Wolvetang, Ernst, Khanna, Kum Kum, Wiesmüller, Lisa, Lavin, Martin F.
Publicado 2015

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

por Becherel, Olivier J., Jakob, Burkhard, Cherry, Amy L., Gueven, Nuri, Fusser, Markus, Kijas, Amanda W., Peng, Cheng, Katyal, Sachin, McKinnon, Peter J., Chen, Junjie, Epe, Bernd, Smerdon, Stephen J., Taucher-Scholz, Gisela, Lavin, Martin F.
Publicado 2010