Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites

por Jakobsen, Martin R, Haasnoot, Joost, Wengel, Jesper, Berkhout, Ben, Kjems, Jørgen
Publicado 2007

Plasmacytoid Dendritic Cells as Cell-Based Therapeutics: A Novel Immunotherapy to Treat Human Immunodeficiency Virus Infection?

por van der Sluis, Renée M., Egedal, Johanne H., Jakobsen, Martin R.
Publicado 2020

Efficient Sleeping Beauty DNA Transposition From DNA Minicircles

por Sharma, Nynne, Cai, Yujia, Bak, Rasmus O, Jakobsen, Martin R, Schrøder, Lisbeth Dahl, Mikkelsen, Jacob Giehm
Publicado 2013

CoRSeq(V3-C): a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm

por Cashin, Kieran, Gray, Lachlan R, Jakobsen, Martin R, Sterjovski, Jasminka, Churchill, Melissa J, Gorry, Paul R
Publicado 2013

Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cells

por Cashin, Kieran, Paukovics, Geza, Jakobsen, Martin R, Østergaard, Lars, Churchill, Melissa J, Gorry, Paul R, Flynn, Jacqueline K
Publicado 2014

Classifying cGAS-STING Activity Links Chromosomal Instability with Immunotherapy Response in Metastatic Bladder Cancer

por Sokač, Mateo, Ahrenfeldt, Johanne, Litchfield, Kevin, Watkins, Thomas B.K., Knudsen, Michael, Dyrskjøt, Lars, Jakobsen, Martin R., Birkbak, Nicolai J.
Publicado 2022

Quantifying Susceptibility of CD4(+) Stem Memory T-Cells to Infection by Laboratory Adapted and Clinical HIV-1 Strains

por Flynn, Jacqueline K., Paukovics, Geza, Cashin, Kieran, Borm, Katharina, Ellett, Anne, Roche, Michael, Jakobsen, Martin R., Churchill, Melissa J., Gorry, Paul R.
Publicado 2014

Targeted, homology-driven gene insertion in stem cells by ZFN-loaded ‘all-in-one’ lentiviral vectors

por Cai, Yujia, Laustsen, Anders, Zhou, Yan, Sun, Chenglong, Anderson, Mads Valdemar, Li, Shengting, Uldbjerg, Niels, Luo, Yonglun, Jakobsen, Martin R, Mikkelsen, Jacob Giehm
Publicado 2016

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

por Roche, Michael, Jakobsen, Martin R, Ellett, Anne, Salimiseyedabad, Hamid, Jubb, Becky, Westby, Mike, Lee, Benhur, Lewin, Sharon R, Churchill, Melissa J, Gorry, Paul R
Publicado 2011

Linkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection

por Cashin, Kieran, Jakobsen, Martin R, Sterjovski, Jasminka, Roche, Michael, Ellett, Anne, Flynn, Jacqueline K, Borm, Katharina, Gouillou, Maelenn, Churchill, Melissa J, Gorry, Paul R
Publicado 2013

Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc

por Borm, Katharina, Jakobsen, Martin R., Cashin, Kieran, Flynn, Jacqueline K., Ellenberg, Paula, Ostergaard, Lars, Lee, Benhur, Churchill, Melissa J., Roche, Michael, Gorry, Paul R.
Publicado 2016

Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection

por Egedal, Johanne H., Xie, Guorui, Packard, Thomas A., Laustsen, Anders, Neidleman, Jason, Georgiou, Konstantinos, Pillai, Satish K., Greene, Warner C., Jakobsen, Martin R., Roan, Nadia R.
Publicado 2021

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

por Dunphy, Gillian, Flannery, Sinéad M., Almine, Jessica F., Connolly, Dympna J., Paulus, Christina, Jønsson, Kasper L., Jakobsen, Martin R., Nevels, Michael M., Bowie, Andrew G., Unterholzner, Leonie
Publicado 2018

Phenotypic and functional characterization of synovial fluid-derived fibroblast-like synoviocytes in rheumatoid arthritis

por Køster, Ditte, Egedal, Johanne Hovgaard, Lomholt, Søren, Hvid, Malene, Jakobsen, Martin R., Müller-Ladner, Ulf, Eibel, Hermann, Deleuran, Bent, Kragstrup, Tue Wenzel, Neumann, Elena, Nielsen, Morten Aagaard
Publicado 2021

Cell-Extrinsic Priming Increases Permissiveness of CD4+ T Cells to Human Immunodeficiency Virus Infection by Increasing C–C Chemokine Receptor Type 5 Co-receptor Expression and Cel...

por Pedersen, Jesper G., Egedal, Johanne H., Packard, Thomas A., Thavachelvam, Karthiga, Xie, Guorui, van der Sluis, Renée Marije, Greene, Warner C., Roan, Nadia R., Jakobsen, Martin R.
Publicado 2021

Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

por Laustsen, Anders, van der Sluis, Renée M, Gris-Oliver, Albert, Hernández, Sabina Sánchez, Cemalovic, Ena, Tang, Hai Q, Pedersen, Lars Henning, Uldbjerg, Niels, Jakobsen, Martin R, Bak, Rasmus O
Publicado 2021

T‐cell derived extracellular vesicles prime macrophages for improved STING based cancer immunotherapy

por Hansen, Aida S., Jensen, Lea S., Gammelgaard, Kristine R., Ryttersgaard, Kristoffer G., Krapp, Christian, Just, Jesper, Jønsson, Kasper L., Jensen, Pia B., Boesen, Thomas, Johansen, Mogens, Etzerodt, Anders, Deleuran, Bent W., Jakobsen, Martin R.
Publicado 2023

Single cell analysis reveals a subset of cytotoxic-like plasmacytoid dendritic cells in people with HIV-1

por Cham, Lamin B., Gunst, Jesper D., Schleimann, Mariane H., Frattari, Giacomo S., Rosas-Umbert, Miriam, Vibholm, Line K., van der Sluis, Renée M., Jakobsen, Martin R., Olesen, Rikke, Lin, Lin, Tolstrup, Martin, Søgaard, Ole S.
Publicado 2023

Whole Exome Sequencing of HIV-1 long-term non-progressors identifies rare variants in genes encoding innate immune sensors and signaling molecules

por Nissen, Sara Konstantin, Christiansen, Mette, Helleberg, Marie, Kjær, Kathrine, Jørgensen, Sofie Eg, Gerstoft, Jan, Katzenstein, Terese L, Benfield, Thomas, Kronborg, Gitte, Larsen, Carsten S, Laursen, Alex, Pedersen, Gitte, Jakobsen, Martin R, Tolstrup, Martin, Mogensen, Trine H
Publicado 2018

T Cells Detect Intracellular DNA but Fail to Induce Type I IFN Responses: Implications for Restriction of HIV Replication

por Berg, Randi K., Rahbek, Stine H., Kofod-Olsen, Emil, Holm, Christian K., Melchjorsen, Jesper, Jensen, David G., Hansen, Anne Louise, Jørgensen, Louise B., Ostergaard, Lars, Tolstrup, Martin, Larsen, Carsten S., Paludan, Søren R., Jakobsen, Martin R., Mogensen, Trine H.
Publicado 2014