THP-1 Cells and Pro-Inflammatory Cytokine Production: An In Vitro Tool for Functional Characterization of NOD1/NOD2 Antagonists

por Jakopin, Žiga, Corsini, Emanuela
Publicado 2019

Iron-Binding and Anti-Fenton Properties of Novel Amino Acid-Derived Cyclic Imide Dioximes

por Mravljak, Janez, Jakopin, Žiga
Publicado 2019

Synthesis of Conformationally Constrained d-Glu-meso-DAP Analogs as Innate Immune Agonists

por Guzelj, Samo, Jakopin, Žiga
Publicado 2020

Nucleotide-Binding Oligomerization Domain 1/Toll-Like Receptor 4 Co-Engagement Promotes Non-Specific Immune Response Against K562 Cancer Cells

por Guzelj, Samo, Jakopin, Žiga
Publicado 2022

Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency

por Guzelj, Samo, Bizjak, Špela, Jakopin, Žiga
Publicado 2022

Novel Scaffolds for Modulation of NOD2 Identified by Pharmacophore-Based Virtual Screening

por Guzelj, Samo, Tomašič, Tihomir, Jakopin, Žiga
Publicado 2022

Harnessing the untapped potential of nucleotide‐binding oligomerization domain ligands for cancer immunotherapy

por Nabergoj, Sanja, Mlinarič‐Raščan, Irena, Jakopin, Žiga
Publicado 2018

Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators

por Guzelj, Samo, Weiss, Matjaž, Slütter, Bram, Frkanec, Ruža, Jakopin, Žiga
Publicado 2022

Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity

por Guzelj, Samo, Šišić, Marcela, Bizjak, Špela, Frkanec, Leo, Frkanec, Ruža, Jakopin, Žiga
Publicado 2022

Design and synthesis of novel 3-triazolyl-1-thiogalactosides as galectin-1, -3 and -8 inhibitors

por van Klaveren, Sjors, Dernovšek, Jaka, Jakopin, Žiga, Anderluh, Marko, Leffler, Hakon, Nilsson, Ulf J., Tomašič, Tihomir
Publicado 2022

Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain

por Hassan, Mujtaba, Baussière, Floriane, Guzelj, Samo, Sundin, Anders P., Håkansson, Maria, Kovačič, Rebeka, Leffler, Hakon, Tomašič, Tihomir, Anderluh, Marko, Jakopin, Žiga, Nilsson, Ulf J.
Publicado 2021

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition

por Lobello, Nadia, Biamonte, Flavia, Pisanu, Maria Elena, Faniello, Maria Concetta, Jakopin, Žiga, Chiarella, Emanuela, Giovannone, Emilia Dora, Mancini, Rita, Ciliberto, Gennaro, Cuda, Giovanni, Costanzo, Francesco
Publicado 2016

Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity

por Guzelj, Samo, Nabergoj, Sanja, Gobec, Martina, Pajk, Stane, Klančič, Veronika, Slütter, Bram, Frkanec, Ruža, Štimac, Adela, Šket, Primož, Plavec, Janez, Mlinarič-Raščan, Irena, Jakopin, Žiga
Publicado 2021

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

por Schijns, Virgil, Majhen, Dragomira, van der Ley, Peter, Thakur, Aneesh, Summerfield, Artur, Berisio, Rita, Nativi, Cristina, Fernández-Tejada, Alberto, Alvarez-Dominguez, Carmen, Gizurarson, Sveinbjörn, Zamyatina, Alla, Molinaro, Antonio, Rosano, Camillo, Jakopin, Žiga, Gursel, Ihsan, McClean, Siobhán
Publicado 2021

Modulation of immune responses using adjuvants to facilitate therapeutic vaccination

por Schijns, Virgil, Fernández‐Tejada, Alberto, Barjaktarović, Žarko, Bouzalas, Ilias, Brimnes, Jens, Chernysh, Sergey, Gizurarson, Sveinbjorn, Gursel, Ihsan, Jakopin, Žiga, Lawrenz, Maria, Nativi, Cristina, Paul, Stephane, Pedersen, Gabriel Kristian, Rosano, Camillo, Ruiz‐de‐Angulo, Ane, Slütter, Bram, Thakur, Aneesh, Christensen, Dennis, Lavelle, Ed C.
Publicado 2020

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

por Pisanu, Maria Elena, Maugeri-Saccà, Marcello, Fattore, Luigi, Bruschini, Sara, De Vitis, Claudia, Tabbì, Eugenio, Bellei, Barbara, Migliano, Emilia, Kovacs, Daniela, Camera, Emanuela, Picardo, Mauro, Jakopin, Ziga, Cippitelli, Claudia, Bartolazzi, Armando, Raffa, Salvatore, Torrisi, Maria Rosaria, Fulciniti, Franco, Ascierto, Paolo A., Ciliberto, Gennaro, Mancini, Rita
Publicado 2018