Synthesis and in vitro Antitumor Potency of (Cyclohexane-1,2-Diamine)Platinum(II) Complexes with Aminotris(Methylenephosphonic Acid) as Bone-Seeking Ligand

por Galanski, Markus, Slaby, Susanna, Jakupec, Michael A., Keppler, Bernhard K.
Publicado 2005

Molecular mode of action of NKP-1339 – a clinically investigated ruthenium-based drug – involves ER- and ROS-related effects in colon carcinoma cell lines

por Flocke, Lea S., Trondl, Robert, Jakupec, Michael A., Keppler, Bernhard K.
Publicado 2016

Biological properties of novel ruthenium- and osmium-nitrosyl complexes with azole heterocycles

por Novak, Maria S., Büchel, Gabriel E., Keppler, Bernhard K., Jakupec, Michael A.
Publicado 2016

NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer

por Trondl, Robert, Heffeter, Petra, Jakupec, Michael A, Berger, Walter, Keppler, Bernhard K
Publicado 2012

Single Spheroid Metabolomics: Optimizing Sample Preparation of Three-Dimensional Multicellular Tumor Spheroids

por Rusz, Mate, Rampler, Evelyn, Keppler, Bernhard K., Jakupec, Michael A., Koellensperger, Gunda
Publicado 2019

KP772 overcomes multiple drug resistance in malignant lymphoma and leukemia cells in vitro by inducing Bcl-2-independent apoptosis and upregulation of Harakiri

por Kater, Lisa, Kater, Benjamin, Jakupec, Michael A., Keppler, Bernhard K., Prokop, Aram
Publicado 2021

Ruthenium- and osmium-arene complexes of 8-substituted indolo[3,2-c]quinolines: Synthesis, X-ray diffraction structures, spectroscopic properties, and antiproliferative activity

por Filak, Lukas K., Göschl, Simone, Hackl, Stefanie, Jakupec, Michael A., Arion, Vladimir B.
Publicado 2012

α-N-Heterocyclic thiosemicarbazones induce ER stress-mediated CHOP activation

por Trondl, Robert, Kowol, Christian R, Arion, Vladimir B, Jakupec, Michael A, Keppler, Bernhard K
Publicado 2010

Diamminetetrakis(carboxylato)platinum(IV) Complexes – Synthesis, Characterization, and Cytotoxicity

por Hoffmeister, Björn R, Adib-Razavi, Mahsa S, Jakupec, Michael A, Galanski, Markus, Keppler, Bernhard K
Publicado 2012

Theoretical Investigations and Density Functional Theory Based Quantitative Structure–Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes

por Varbanov, Hristo P., Jakupec, Michael A., Roller, Alexander, Jensen, Frank, Galanski, Markus, Keppler, Bernhard K.
Publicado 2012

Biological evaluation of novel thiomaltol-based organometallic complexes as topoisomerase IIα inhibitors

por Legina, Maria S., Nogueira, Juan J., Kandioller, Wolfgang, Jakupec, Michael A., González, Leticia, Keppler, Bernhard K.
Publicado 2020

Highly Aromatic Flavan-3-ol Derivatives from Palaeotropical Artocarpus lacucha Buch.-Ham Possess Radical Scavenging and Antiproliferative Properties

por Songoen, Weerasak, Phanchai, Witthawat, Brecker, Lothar, Wenisch, Dominik, Jakupec, Michael A., Pluempanupat, Wanchai, Schinnerl, Johann
Publicado 2021

Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells

por Mühlgassner, Gerhard, Bartel, Caroline, Schmid, Wolfgang F., Jakupec, Michael A., Arion, Vladimir B., Keppler, Bernhard K.
Publicado 2012

Systematic Study on the Cytotoxic Potency of Commonly Used Dimeric Metal Precursors in Human Cancer Cell Lines

por Geisler, Heiko, Harringer, Sophia, Wenisch, Dominik, Urban, Richard, Jakupec, Michael A., Kandioller, Wolfgang, Keppler, Bernhard K.
Publicado 2022

Combination of Drug Delivery Properties of PAMAM Dendrimers and Cytotoxicity of Platinum(IV) Complexes—A More Selective Anticancer Treatment?

por Lerchbammer-Kreith, Yvonne, Hejl, Michaela, Vician, Petra, Jakupec, Michael A., Berger, Walter, Galanski, Mathea S., Keppler, Bernhard K.
Publicado 2023

En Route to Osmium Analogues of KP1019: Synthesis, Structure, Spectroscopic Properties and Antiproliferative Activity of trans-[Os(IV)Cl(4)(Hazole)(2)]

por Büchel, Gabriel E., Stepanenko, Iryna N., Hejl, Michaela, Jakupec, Michael A., Keppler, Bernhard K., Arion, Vladimir B.
Publicado 2011

A highly cytotoxic modified paullone ligand bearing a TEMPO free-radical unit and its copper(ii) complex as potential hR2 RNR inhibitors

por Dobrov, Anatolie, Göschl, Simone, Jakupec, Michael A., Popović-Bijelić, Ana, Gräslund, Astrid, Rapta, Peter, Arion, Vladimir B.
Publicado 2013

NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs

por Legin, Anton A., Schintlmeister, Arno, Jakupec, Michael A., Galanski, Mathea S., Lichtscheidl, Irene, Wagner, Michael, Keppler, Bernhard K.
Publicado 2014

Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy

por Filak, Lukas K., Mühlgassner, Gerhard, Jakupec, Michael A., Heffeter, Petra, Berger, Walter, Arion, Vladimir B., Keppler, Bernhard K.
Publicado 2010

Synthesis and characterization of novel bis(carboxylato)dichloridobis(ethylamine)platinum(IV) complexes with higher cytotoxicity than cisplatin

por Varbanov, Hristo, Valiahdi, Seied M., Legin, Anton A., Jakupec, Michael A., Roller, Alexander, Galanski, Mathea S., Keppler, Bernhard K.
Publicado 2011