Incorporating Target Shedding Into a Minimal PBPK–TMDD Model for Monoclonal Antibodies

por Li, L, Gardner, I, Rose, R, Jamei, M
Publicado 2014

Interaction Between Domperidone and Ketoconazole: Toward Prediction of Consequent QTc Prolongation Using Purely In Vitro Information

por Mishra, H, Polak, S, Jamei, M, Rostami-Hodjegan, A
Publicado 2014

Representation of [Formula: see text] -Bernstein polynomials in terms of [Formula: see text] -Jacobi polynomials

por Soleyman, F, Area, I, Masjed-Jamei, M, Nieto, JJ
Publicado 2017

A Tutorial on Pharmacodynamic Scripting Facility in Simcyp

por Abduljalil, K, Edwards, D, Barnett, A, Rose, RH, Cain, T, Jamei, M
Publicado 2016

Application of a Physiologically Based Pharmacokinetic Model to Predict OATP1B1-Related Variability in Pharmacodynamics of Rosuvastatin

por Rose, R H, Neuhoff, S, Abduljalil, K, Chetty, M, Rostami-Hodjegan, A, Jamei, M
Publicado 2014

A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

por Jamei, M., Bajot, F., Neuhoff, S., Barter, Z., Yang, J., Rostami-Hodjegan, A., Rowland-Yeo, K.
Publicado 2013

Development of a Multicompartment Permeability-Limited Lung PBPK Model and Its Application in Predicting Pulmonary Pharmacokinetics of Antituberculosis Drugs

por Gaohua, L, Wedagedera, J, Small, BG, Almond, L, Romero, K, Hermann, D, Hanna, D, Jamei, M, Gardner, I
Publicado 2015

Evaluation of an In Silico PBPK Post-Bariatric Surgery Model through Simulating Oral Drug Bioavailability of Atorvastatin and Cyclosporine

por Darwich, A S, Pade, D, Rowland-Yeo, K, Jamei, M, Åsberg, A, Christensen, H, Ashcroft, D M, Rostami-Hodjegan, A
Publicado 2013

Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation: Report of an FDA Public Workshop

por Zhang, X, Duan, J, Kesisoglou, F, Novakovic, J, Amidon, GL, Jamei, M, Lukacova, V, Eissing, T, Tsakalozou, E, Zhao, L, Lionberger, R
Publicado 2017