Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

por Melehani, Jason H., James, David B. A., DuMont, Ashley L., Torres, Victor J., Duncan, Joseph A.
Publicado 2015

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

por Scherr, Tyler D., Hanke, Mark L., Huang, Ouwen, James, David B. A., Horswill, Alexander R., Bayles, Kenneth W., Fey, Paul D., Torres, Victor J., Kielian, Tammy
Publicado 2015

The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

por Tuffs, Stephen W., James, David B. A., Bestebroer, Jovanka, Richards, Amy C., Goncheva, Mariya I., O’Shea, Marie, Wee, Bryan A., Seo, Keun Seok, Schlievert, Patrick M., Lengeling, Andreas, van Strijp, Jos A., Torres, Victor J., Fitzgerald, J. Ross
Publicado 2017

All major cholesterol-dependent cytolysins use glycans as cellular receptors

por Shewell, Lucy K., Day, Christopher J., Jen, Freda E.-C., Haselhorst, Thomas, Atack, John M., Reijneveld, Josephine F., Everest-Dass, Arun, James, David B. A., Boguslawski, Kristina M., Brouwer, Stephan, Gillen, Christine M., Luo, Zhenyao, Kobe, Bostjan, Nizet, Victor, von Itzstein, Mark, Walker, Mark J., Paton, Adrienne W., Paton, James C., Torres, Victor J., Jennings, Michael P.
Publicado 2020

Genetic variation of staphylococcal LukAB toxin determines receptor tropism

por Perelman, Sofya S., James, David B.A., Boguslawski, Kristina M., Nelson, Chase W., Ilmain, Juliana K., Zwack, Erin E., Prescott, Rachel A., Mohamed, Adil, Tam, Kayan, Chan, Rita, Narechania, Apurva, Pawline, Miranda B., Vozhilla, Nikollaq, Moustafa, Ahmed M., Kim, Sang Y., Dittmann, Meike, Ekiert, Damian C., Bhabha, Gira, Shopsin, Bo, Planet, Paul J., Koralov, Sergei B., Torres, Victor J.
Publicado 2021