SAT-283 Generation of a Long-Acting Human Growth Hormone Receptor Antagonist by Site-Specific Pegylation

por Wang, Yue, Langley, Ries J, Tamshen, Kyle, Maynard, Heather D, Jamieson, Stephen M F, Perry, Jo K
Publicado 2020

Calcium Enabled Remote Loading of a Weak Acid Into pH-sensitive Liposomes and Augmented Cytosolic Delivery to Cancer Cells via the Proton Sponge Effect

por Yang, Mimi M., Yarragudi, Sasi Bhushan, Jamieson, Stephen M. F., Tang, Mingtan, Wilson, William R., Wu, Zimei
Publicado 2022

The Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer

por Yin, Yarong Diana, Fu, Melissa, Brooke, Darby G., Heinrich, Daniel M., Denny, William A., Jamieson, Stephen M. F.
Publicado 2014

Inhibitors of pan-PI3K Signaling Synergize with BRAF or MEK Inhibitors to Prevent BRAF-Mutant Melanoma Cell Growth

por Sweetlove, Melanie, Wrightson, Emma, Kolekar, Sharada, Rewcastle, Gordon W., Baguley, Bruce C., Shepherd, Peter R., Jamieson, Stephen M. F.
Publicado 2015

Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide †

por Arshad, Jahanzaib, Tong, Kelvin K. H., Movassaghi, Sanam, Söhnel, Tilo, Jamieson, Stephen M. F., Hanif, Muhammad, Hartinger, Christian G.
Publicado 2021

Cavity-Containing [Fe(2)L(3)](4+) Helicates: An Examination of Host-Guest Chemistry and Cytotoxicity

por Lisboa, Lynn S., Riisom, Mie, Vasdev, Roan A. S., Jamieson, Stephen M. F., Wright, L. James, Hartinger, Christian G., Crowley, James D.
Publicado 2021

Corrigendum: Cavity-Containing [Fe(2)L(3)](4+) Helicates: An Examination of Host-Guest Chemistry and Cytotoxicity

por Lisboa, Lynn S., Riisom, Mie, Vasdev, Roan A. S., Jamieson, Stephen M. F., Wright, L. James, Hartinger, Christian G., Crowley, James D.
Publicado 2021

Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers

por Liew, Lydia P., Shome, Avik, Wong, Way W., Hong, Cho R., Hicks, Kevin O., Jamieson, Stephen M. F., Hay, Michael P.
Publicado 2023

Mechanisms of resistance to trastuzumab emtansine (T-DM1) in HER2-positive breast cancer

por Hunter, Francis W., Barker, Hilary R., Lipert, Barbara, Rothé, Françoise, Gebhart, Géraldine, Piccart-Gebhart, Martine J., Sotiriou, Christos, Jamieson, Stephen M. F.
Publicado 2019

Thiourea-Derived Chelating Ligands and Their Organometallic Compounds: Investigations into Their Anticancer Activity

por Tong, Kelvin K. H., Hanif, Muhammad, Lovett, James H., Hummitzsch, Katja, Harris, Hugh H., Söhnel, Tilo, Jamieson, Stephen M. F., Hartinger, Christian G.
Publicado 2020

Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

por Lee, Tet Woo, Lai, Amy, Harms, Julia K., Singleton, Dean C., Dickson, Benjamin D., Macann, Andrew M. J., Hay, Michael P., Jamieson, Stephen M. F.
Publicado 2020

Synthetic Strategy Towards Heterodimetallic Half-Sandwich Complexes Based on a Symmetric Ditopic Ligand

por Green, Lewis P. M., Steel, Tasha R., Riisom, Mie, Hanif, Muhammad, Söhnel, Tilo, Jamieson, Stephen M. F., Wright, L. James, Crowley, James D., Hartinger, Christian G.
Publicado 2021

High Antiproliferative Activity of Hydroxythiopyridones over Hydroxypyridones and Their Organoruthenium Complexes

por Shakil, Md. Salman, Parveen, Shahida, Rana, Zohaib, Walsh, Fearghal, Movassaghi, Sanam, Söhnel, Tilo, Azam, Mayur, Shaheen, Muhammad Ashraf, Jamieson, Stephen M. F., Hanif, Muhammad, Rosengren, Rhonda J., Hartinger, Christian G.
Publicado 2021

Impact of Tumour Hypoxia on Evofosfamide Sensitivity in Head and Neck Squamous Cell Carcinoma Patient-Derived Xenograft Models

por Harms, Julia K., Lee, Tet-Woo, Wang, Tao, Lai, Amy, Kee, Dennis, Chaplin, John M., McIvor, Nick P., Hunter, Francis W., Macann, Andrew M. J., Wilson, William R., Jamieson, Stephen M.F.
Publicado 2019

Incorporation of β‐Alanine in Cu(II) ATCUN Peptide Complexes Increases ROS Levels, DNA Cleavage and Antiproliferative Activity

por Heinrich, Julian, Bossak‐Ahmad, Karolina, Riisom, Mie, Haeri, Haleh H., Steel, Tasha R., Hergl, Vinja, Langhans, Alexander, Schattschneider, Corinna, Barrera, Jannis, Jamieson, Stephen M. F., Stein, Matthias, Hinderberger, Dariush, Hartinger, Christian G., Bal, Wojciech, Kulak, Nora
Publicado 2021

Metal-Dependent Cytotoxic and Kinesin Spindle Protein Inhibitory Activity of Ru, Os, Rh, and Ir Half-Sandwich Complexes of Ispinesib-Derived Ligands

por Łomzik, Michał, Hanif, Muhammad, Budniok, Aleksandra, Błauż, Andrzej, Makal, Anna, Tchoń, Daniel M., Leśniewska, Barbara, Tong, Kelvin K. H., Movassaghi, Sanam, Söhnel, Tilo, Jamieson, Stephen M. F., Zafar, Ayesha, Reynisson, Jóhannes, Rychlik, Błażej, Hartinger, Christian G., Plażuk, Damian
Publicado 2020

Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors

por Rewcastle, Gordon W, Kolekar, Sharada, Buchanan, Christina M, Gamage, Swarna A, Giddens, Anna C, Tsang, Kit Y, Kendall, Jackie D, Singh, Ripudaman, Lee, Woo-Jeong, Smith, Greg C, Han, Weiping, Matthews, David J, Denny, William A, Shepherd, Peter R, Jamieson, Stephen M.F
Publicado 2017

Exploration of a Series of 5-Arylidene-2-thioxoimidazolidin-4-ones as Inhibitors of the Cytolytic Protein Perforin

por Spicer, Julie A., Lena, Gersande, Lyons, Dani M., Huttunen, Kristiina M., Miller, Christian K., O’Connor, Patrick D., Bull, Matthew, Helsby, Nuala, Jamieson, Stephen M. F., Denny, William A., Ciccone, Annette, Browne, Kylie A., Lopez, Jamie A., Rudd-Schmidt, Jesse, Voskoboinik, Ilia, Trapani, Joseph A.
Publicado 2013

Preclinical Activity and Pharmacokinetic/Pharmacodynamic Relationship for a Series of Novel Benzenesulfonamide Perforin Inhibitors

por Gartlan, Kate H., Jaiswal, Jagdish K., Bull, Matthew R., Akhlaghi, Hedieh, Sutton, Vivien R., Alexander, Kylie A., Chang, Karshing, Hill, Geoffrey R., Miller, Christian K., O’Connor, Patrick D., Jose, Jiney, Trapani, Joseph A., Charman, Susan A., Spicer, Julie A., Jamieson, Stephen M. F.
Publicado 2022

Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

por Jamieson, Stephen M.F., Tsai, Peter, Kondratyev, Maria K., Budhani, Pratha, Liu, Arthur, Senzer, Neil N., Chiorean, E. Gabriela, Jalal, Shadia I., Nemunaitis, John J., Kee, Dennis, Shome, Avik, Wong, Way W., Li, Dan, Poonawala-Lohani, Nooriyah, Kakadia, Purvi M., Knowlton, Nicholas S., Lynch, Courtney R.H., Hong, Cho R., Lee, Tet Woo, Grénman, Reidar A., Caporiccio, Laura, McKee, Trevor D., Zaidi, Mark, Butt, Sehrish, Macann, Andrew M.J., McIvor, Nicholas P., Chaplin, John M., Hicks, Kevin O., Bohlander, Stefan K., Wouters, Bradly G., Hart, Charles P., Print, Cristin G., Wilson, William R., Curran, Michael A., Hunter, Francis W.
Publicado 2023