Pediatric Non-Alcoholic Fatty Liver Disease: Nutritional Origins and Potential Molecular Mechanisms

por Mandala, Ashok, Janssen, Rachel C., Palle, Sirish, Short, Kevin R., Friedman, Jacob E.
Publicado 2020

TET‐Like Oxidation in 5‐Methylcytosine and Derivatives: A Computational and Experimental Study

por Jonasson, Niko S. W., Janßen, Rachel, Menke, Annika, Zott, Fabian L., Zipse, Hendrik, Daumann, Lena J.
Publicado 2021

Maternal Fat-1 Transgene Protects Offspring from Excess Weight Gain, Oxidative Stress, and Reduced Fatty Acid Oxidation in Response to High-Fat Diet

por Boyle, Kristen E., Magill-Collins, Margaret J., Newsom, Sean A., Janssen, Rachel C., Friedman, Jacob E.
Publicado 2020

Transgenic Increase in N-3/N-6 Fatty Acid Ratio Reduces Maternal Obesity-Associated Inflammation and Limits Adverse Developmental Programming in Mice

por Heerwagen, Margaret J. R., Stewart, Michael S., de la Houssaye, Becky A., Janssen, Rachel C., Friedman, Jacob E.
Publicado 2013

Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD

por Mandala, Ashok, Dobrinskikh, Evgenia, Janssen, Rachel C., Fiehn, Oliver, D’Alessandro, Angelo, Friedman, Jacob E., Jonscher, Karen R.
Publicado 2022

Gestational Diabetes Is Characterized by Reduced Mitochondrial Protein Expression and Altered Calcium Signaling Proteins in Skeletal Muscle

por Boyle, Kristen E., Hwang, Hyonson, Janssen, Rachel C., DeVente, James M., Barbour, Linda A., Hernandez, Teri L., Mandarino, Lawrence J., Lappas, Martha, Friedman, Jacob E.
Publicado 2014

Altered gene expression and metabolism in fetal umbilical cord mesenchymal stem cells correspond with differences in 5-month-old infant adiposity gain

por Baker, Peter R., Patinkin, Zachary W., Shapiro, Allison L. B., de la Houssaye, Becky A., Janssen, Rachel C., Vanderlinden, Lauren A., Dabelea, Dana, Friedman, Jacob E.
Publicado 2017

Maternal Western diet exposure increases periportal fibrosis beginning in utero in nonhuman primate offspring

por Nash, Michael J., Dobrinskikh, Evgenia, Newsom, Sean A., Messaoudi, Ilhem, Janssen, Rachel C., Aagaard, Kjersti M., McCurdy, Carrie E., Gannon, Maureen, Kievit, Paul, Friedman, Jacob E., Wesolowski, Stephanie R.
Publicado 2021

Gestational Diabetes Is Uniquely Associated With Altered Early Seeding of the Infant Gut Microbiota

por Soderborg, Taylor K., Carpenter, Charles M., Janssen, Rachel C., Weir, Tiffany L., Robertson, Charles E., Ir, Diana, Young, Bridget E., Krebs, Nancy F., Hernandez, Teri L., Barbour, Linda A., Frank, Daniel N., Kroehl, Miranda, Friedman, Jacob E.
Publicado 2020

Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver

por Sugino, Kameron Y., Mandala, Ashok, Janssen, Rachel C., Gurung, Sunam, Trammell, MaJoi, Day, Michael W., Brush, Richard S., Papin, James F., Dyer, David W., Agbaga, Martin-Paul, Friedman, Jacob E., Castillo-Castrejon, Marisol, Jonscher, Karen R., Myers, Dean A.
Publicado 2022

Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants

por Boyle, Kristen E., Patinkin, Zachary W., Shapiro, Allison L.B., Bader, Carly, Vanderlinden, Lauren, Kechris, Katerina, Janssen, Rachel C., Ford, Rebecca J., Smith, Brennan K., Steinberg, Gregory R., Davidson, Elizabeth J., Yang, Ivana V., Dabelea, Dana, Friedman, Jacob E.
Publicado 2017

Maternal Western diet is associated with distinct preclinical pediatric NAFLD phenotypes in juvenile nonhuman primate offspring

por Nash, Michael J., Dobrinskikh, Evgenia, Janssen, Rachel C., Lovell, Mark A., Schady, Deborah A., Levek, Claire, Jones, Kenneth L., D’Alessandro, Angelo, Kievit, Paul, Aagaard, Kjersti M., McCurdy, Carrie E., Gannon, Maureen, Friedman, Jacob E., Wesolowski, Stephanie R.
Publicado 2023

Switching obese mothers to a healthy diet improves fetal hypoxemia, hepatic metabolites, and lipotoxicity in non-human primates

por Wesolowski, Stephanie R., Mulligan, Christopher M., Janssen, Rachel C., Baker, Peter R., Bergman, Bryan C., D'Alessandro, Angelo, Nemkov, Travis, Maclean, Kenneth N., Jiang, Hua, Dean, Tyler A., Takahashi, Diana L., Kievit, Paul, McCurdy, Carrie E., Aagaard, Kjersti M., Friedman, Jacob E.
Publicado 2018

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring

por Nash, Michael J., Dobrinskikh, Evgenia, Soderborg, Taylor K., Janssen, Rachel C., Takahashi, Diana L., Dean, Tyler A., Varlamov, Oleg, Hennebold, Jon D., Gannon, Maureen, Aagaard, Kjersti M., McCurdy, Carrie E., Kievit, Paul, Bergman, Bryan C., Jones, Kenneth L., Pietras, Eric M., Wesolowski, Stephanie R., Friedman, Jacob E.
Publicado 2023

Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues

por Wang, Hong, Knaub, Leslie A., Jensen, Dalan R., Jung, Dae Young, Hong, Eun-Gyoung, Ko, Hwi-Jin, Coates, Alison M., Goldberg, Ira J., de la Houssaye, Becky A., Janssen, Rachel C., McCurdy, Carrie E., Rahman, Shaikh M., Choi, Cheol Soo, Shulman, Gerald I., Kim, Jason K., Friedman, Jacob E., Eckel, Robert H.
Publicado 2009

The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

por Soderborg, Taylor K., Clark, Sarah E., Mulligan, Christopher E., Janssen, Rachel C., Babcock, Lyndsey, Ir, Diana, Young, Bridget, Krebs, Nancy, Lemas, Dominick J., Johnson, Linda K., Weir, Tiffany, Lenz, Laurel L., Frank, Daniel N., Hernandez, Teri L., Kuhn, Kristine A., D’Alessandro, Angelo, Barbour, Linda A., El Kasmi, Karim C., Friedman, Jacob E.
Publicado 2018

Author Correction: The gut microbiota in infants of obese mothers increases inflammation and susceptibility to NAFLD

por Soderborg, Taylor K., Clark, Sarah E., Mulligan, Christopher E., Janssen, Rachel C., Babcock, Lyndsey, Ir, Diana, Young, Bridget, Krebs, Nancy F., Lemas, Dominick J., Johnson, Linda K., Weir, Tiffany, Lenz, Laurel L., Frank, Daniel N., Hernandez, Teri L., Kuhn, Kristine A., D’Alessandro, Angelo, Barbour, Linda A., El Kasmi, Karim C., Friedman, Jacob E.
Publicado 2019

Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice

por Friedman, Jacob E., Dobrinskikh, Evgenia, Alfonso‐Garcia, Alba, Fast, Alexander, Janssen, Rachel C., Soderborg, Taylor K., Anderson, Aimee L., Reisz, Julie A., D'Alessandro, Angelo, Frank, Daniel N., Robertson, Charles E., de la Houssaye, Becky A., Johnson, Linda K., Orlicky, David J., Wang, Xiaoxin X., Levi, Moshe, Potma, Eric O., El Kasmi, Karim C., Jonscher, Karen R.
Publicado 2018