Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase–TPX2 protein–protein interaction

por Cole, Daniel J., Janecek, Matej, Stokes, Jamie E., Rossmann, Maxim, Faver, John C., McKenzie, Grahame J., Venkitaraman, Ashok R., Hyvönen, Marko, Spring, David R., Huggins, David J., Jorgensen, William L.
Publicado 2017

Modified cyclodextrins as broad-spectrum antivirals

por Jones, Samuel T., Cagno, Valeria, Janeček, Matej, Ortiz, Daniel, Gasilova, Natalia, Piret, Jocelyne, Gasbarri, Matteo, Constant, David A., Han, Yanxiao, Vuković, Lela, Král, Petr, Kaiser, Laurent, Huang, Song, Constant, Samuel, Kirkegaard, Karla, Boivin, Guy, Stellacci, Francesco, Tapparel, Caroline
Publicado 2020

Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2

por Janeček, Matej, Rossmann, Maxim, Sharma, Pooja, Emery, Amy, Huggins, David J., Stockwell, Simon R., Stokes, Jamie E., Tan, Yaw S., Almeida, Estrella Guarino, Hardwick, Bryn, Narvaez, Ana J., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.
Publicado 2016