Mouse Transplant Models for Evaluating the Oncogenic Risk of a Self-Inactivating XSCID Lentiviral Vector

por Zhou, Sheng, Ma, Zhijun, Lu, Taihe, Janke, Laura, Gray, John T., Sorrentino, Brian P.
Publicado 2013

Mapping of MN1 Sequences Necessary for Myeloid Transformation

por Kandilci, Ayten, Surtel, Jacqueline, Janke, Laura, Neale, Geoffrey, Terranova, Sabrina, Grosveld, Gerard C.
Publicado 2013

Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation

por Leung, Wai-Hang, Vong, Queenie P., Lin, Wenwei, Janke, Laura, Chen, Taosheng, Leung, Wing
Publicado 2013

Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes

por Zhou, Sheng, Fatima, Soghra, Ma, Zhijun, Wang, Yong-Dong, Lu, Taihe, Janke, Laura J, Du, Yang, Sorrentino, Brian P
Publicado 2016

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice

por Finch, Emily R., Payton, Monique A., Jenkins, David A., Cai, Xiangjun, Li, Lie, Karol, Seth E., Relling, Mary V., Janke, Laura J.
Publicado 2020

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

por Treanor, Louise M., Zhou, Sheng, Janke, Laura, Churchman, Michelle L., Ma, Zhijun, Lu, Taihe, Chen, Shann-Ching, Mullighan, Charles G., Sorrentino, Brian P.
Publicado 2014

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

por Liu, Chengcheng, Janke, Laura J., Kawedia, Jitesh D., Ramsey, Laura B., Cai, Xiangjun, Mattano, Leonard A., Boyd, Kelli L., Funk, Amy J., Relling, Mary V.
Publicado 2016

A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

por Inoue, Akira, Janke, Laura J, Gudenas, Brian L, Jin, Hongjian, Fan, Yiping, Paré, Joshua, Clay, Michael R, Northcott, Paul A, Hirbe, Angela C, Cao, Xinwei
Publicado 2021

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

por Karol, Seth E., Janke, Laura J., Panetta, John C., Ramsey, Laura B., Cai, Xiangjun, Payton, Monique A., Jenkins, David A., Evans, William E., Relling, Mary V.
Publicado 2019

Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice

por Diouf, Barthelemy, Devaraju, Prakash, Janke, Laura J., Fan, Yiping, Frase, Sharon, Eddins, Donnie, Peters, Jennifer L., Kim, Jieun, Pei, Deqing, Cheng, Cheng, Zakharenko, Stanislav S., Evans, William E.
Publicado 2016

ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer

por Harwood, Franklin C., Klein Geltink, Ramon I., O’Hara, Brendan P., Cardone, Monica, Janke, Laura, Finkelstein, David, Entin, Igor, Paul, Leena, Houghton, Peter J., Grosveld, Gerard C.
Publicado 2018

Role of Vitamins A and D in BCR-ABL Arf(−/−) Acute Lymphoblastic Leukemia

por Annu, Kavya, Cline, Cynthia, Yasuda, Kazuto, Ganguly, Samit, Pesch, Andrea, Cooper, Brittany, Janke, Laura, Payton, Monique, Mukherjee, Kamalika, Surman, Sherri L., Hurwitz, Julia L., Schuetz, Erin G.
Publicado 2020

Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death

por Morgan, Jessica A., Lynch, John, Panetta, John C., Wang, Yao, Frase, Sharon, Bao, Ju, Zheng, Jie, Opferman, Joseph T., Janke, Laura, Green, Daniel M., Chemaitilly, Wassim, Schuetz, John D.
Publicado 2015

Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia

por Klco, Jeffery, Thomas, Melvin, Qi, Wenqing, Walsh, Michael, Ma, Jing, Westover, Tamara, Abdelhamed, Sherif, Ezzell, Lauren, Rolle, Chandra, Xiong, Emily, Rosikiewicz, Wojciech, Xu, Beisi, Pruett-Miller, Shondra, Loughran, Allister, Janke, Laura
Publicado 2023

Regulated lysosomal exocytosis mediates cancer progression

por Machado, Eda, White-Gilbertson, Shai, van de Vlekkert, Diantha, Janke, Laura, Moshiach, Simon, Campos, Yvan, Finkelstein, David, Gomero, Elida, Mosca, Rosario, Qiu, Xiaohui, Morton, Christopher L., Annunziata, Ida, d’Azzo, Alessandra
Publicado 2015

G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL

por Iacobucci, Ilaria, Fukano, Reiji, D. Friske, Jake, Qu, Chunxu, Janke, Laura J., Zhao, Yaqi, Baviskar, Pradyuamna, A. Backhaus, Emily, Chockley, Peter, Seth, Aman, Laird, A. Douglas, Advani, Anjali S., Mullighan, Charles G.
Publicado 2022

3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates

por Bonner, Melissa A., Morales-Hernández, Antonio, Zhou, Sheng, Ma, Zhijun, Condori, Jose, Wang, Yong-Dong, Fatima, Soghra, Palmer, Lance E., Janke, Laura J., Fowler, Stephanie, Sorrentino, Brian P., McKinney-Freeman, Shannon
Publicado 2021

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

por Ramsey, Laura B., Janke, Laura J., Payton, Monique A., Cai, Xiangjun, Paugh, Steven W., Karol, Seth E., Kamdem, Landry Kamdem, Cheng, Cheng, Williams, Richard T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2015

Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice

por Abdelhamed, Sherif, Thomas, Melvin E., Westover, Tamara, Umeda, Masayuki, Xiong, Emily, Rolle, Chandra, Walsh, Michael P., Wu, Huiyun, Schwartz, Jason R., Valentine, Virginia, Valentine, Marcus, Pounds, Stanley, Ma, Jing, Janke, Laura J., Klco, Jeffery M.
Publicado 2022

Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity

por Zong, Xinying, Hao, Xiaolei, Xu, Beisi, Crawford, Jeremy Chase, Wright, Shaela, Li, Jun, Zhang, Yang, Bai, Lu, He, Minghong, Jiang, Menglin, Fan, Yiping, Connelly, Jon P., Pruett-Miller, Shondra M., Berns, Hartmut, Janke, Laura, Li, Chunliang, Feng, Yongqiang
Publicado 2021